The influence of cell morphology on the compressive fatigue behavior of Ti-6Al-4V meshes fabricated by electron beam melting

Zhao, Shuai; Li, S.J.; Hou, Wentao; Hao, Yulin; Yang, Rui; Misra, R.D.K.

doi:10.1016/j.jmbbm.2016.01.034

Cited by 215 publications

(108 citation statements)

References 41 publications

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“…For the gradient structures, the fracture initiated from the thinnest struts, that is at the top and bottom plane for Dense-In and in the middle for Dense-Out. This diagonal shear collapse of uniform structures is typical behavior of BCC structures [52][53][54] and other structures with different cell geometries [55,56] owing to strut bending at lattice joints [51]. …”

Section: Mechanical Properties Of Porous Scaffoldsmentioning

confidence: 84%

Mechanical Properties and In Vitro Behavior of Additively Manufactured and Functionally Graded Ti6Al4V Porous Scaffolds

Onal

Frith

Jurg

et al. 2018

Metals

122

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Abstract:Functionally graded lattice structures produced by additive manufacturing are promising for bone tissue engineering. Spatial variations in their porosity are reported to vary the stiffness and make it comparable to cortical or trabecular bone. However, the interplay between the mechanical properties and biological response of functionally graded lattices is less clear. Here we show that by designing continuous gradient structures and studying their mechanical and biological properties simultaneously, orthopedic implant design can be improved and guidelines can be established. Our continuous gradient structures were generated by gradually changing the strut diameter of a body centered cubic (BCC) unit cell. This approach enables a smooth transition between unit cell layers and minimizes the effect of stress discontinuity within the scaffold. Scaffolds were fabricated using selective laser melting (SLM) and underwent mechanical and in vitro biological testing. Our results indicate that optimal gradient structures should possess small pores in their core (~900 µm) to increase their mechanical strength whilst large pores (~1100 µm) should be utilized in their outer surface to enhance cell penetration and proliferation. We suggest this approach could be widely used in the design of orthopedic implants to maximize both the mechanical and biological properties of the implant.

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Section: Mechanical Properties Of Porous Scaffoldsmentioning

confidence: 84%

Mechanical Properties and In Vitro Behavior of Additively Manufactured and Functionally Graded Ti6Al4V Porous Scaffolds

Onal

Frith

Jurg

et al. 2018

Metals

122

View full text Add to dashboard Cite

show abstract

“…Recently, the effect of cell shape on mechanical properties and deformation mechanism was studied in EBM fabricated Ti-6Al-4V reticulated mesh structure with different unit cell elements (cubic, G7, rhombic dodecahedron) [75]. These different unit cells provide a means to effectively balance the strength, elastic modulus and degradation behavior in cellular solids.…”

Section: Role Of Unit Cell Designmentioning

confidence: 99%

“…On increasing the buckling deformation on the struts via design of cell shape, the cyclic ratcheting rate of the meshes during cyclic deformation was decreased and the compressive fatigue strength was increased. While increasing the bending deformation of the struts, the contribution of fatigue crack growth in the struts led to significant fatigue damage of mesh [75]. Moreover, the presence of rough surface and pores contained in the struts significantly deteriorated the compressive fatigue strength of the struts.…”

Section: Role Of Unit Cell Designmentioning

confidence: 99%

“…It was demonstrated that Ti-6Al-4V cellular materials with high strength, low modulus, and desirable mechanical deformation behavior can be processed by EBM, involving tuning of cell design (Fig. 3) [75]. Table 2 summaries the properties of titanium alloy fabricated with different unit cell design by EBM [75].…”

Section: Role Of Unit Cell Designmentioning

confidence: 99%

“…3) [75]. Table 2 summaries the properties of titanium alloy fabricated with different unit cell design by EBM [75].…”

Section: Role Of Unit Cell Designmentioning

confidence: 99%

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Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Nune

Misra

2017

Sci. China Mater.

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We elucidate here the process-structure-property relationships in three-dimensional (3D) implantable titanium alloy biomaterials processed by electron beam melting (EBM) that is based on the principle of additive manufacturing. The conventional methods for processing of biomedical devices including freeze casting and sintering are limited because of the difficulties in adaptation at the host site and difference in the micro/macrostructure, mechanical, and physical properties with the host tissue. In this regard, EBM has a unique advantage of processing patient-specific complex designs, which can be either obtained from the computed tomography (CT) scan of the defect site or through a computeraided design (CAD) program. This review introduces and summarizes the evolution and underlying reasons that have motivated 3D printing of scaffolds for tissue regeneration. The overview comprises of two parts for obtaining ultimate functionalities. The first part focuses on obtaining the ultimate functionalities in terms of mechanical properties of 3D titanium alloy scaffolds fabricated by EBM with different characteristics based on design, unit cell, processing parameters, scan speed, porosity, and heat treatment. The second part focuses on the advancement of enhancing biological responses of these 3D scaffolds and the influence of surface modification on cell-material interactions. The overview concludes with a discussion on the clinical trials of these 3D porous scaffolds illustrating their potential in meeting the current needs of the biomedical industry.

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Open Celled Porous Titanium

Shbeh

Goodall

2017

Adv Eng Mater

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[**] One of the authours (MMS) would like to acknowledge a studentship from the Iraqi Ministry of Higher Education and Scientific Research.Among the porous metals, those made of titanium attract particular attention due to the interesting properties of this element. This review examines the state of research understanding and technological development of these materials, in terms of processing capability, resultant structure and properties and the most advanced applications under development. The impact of the rise of additive manufacturing techniques on these materials is discussed, along with the likely future directions required for these materials to find practical applications on a large scale.

show abstract

The influence of cell morphology on the compressive fatigue behavior of Ti-6Al-4V meshes fabricated by electron beam melting

Cited by 215 publications

References 41 publications

Mechanical Properties and In Vitro Behavior of Additively Manufactured and Functionally Graded Ti6Al4V Porous Scaffolds

Mechanical Properties and In Vitro Behavior of Additively Manufactured and Functionally Graded Ti6Al4V Porous Scaffolds

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Open Celled Porous Titanium

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