The influence of bisphenol antioxidants on thermo-oxidative degradation of plasticised poly(vinyl chloride)

Mukmeneva, N. A.; Готлиб, Елена; Verizhnikov, M; Nagumanova, G; Grinberg, L.P; Chakirov, R.R.

doi:10.1016/s0141-3910(01)00115-x

Cited by 6 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, dominantly positive associations, but also some equivocal results, but only one negative association, were found between BPA and oxidative stress biomarkers. Total antioxidant activity (no significant outcomes) --- 1 For antioxidants (consumed during oxidative stress), but not antioxidant enzymes, a negative statistical association with BPA is regarded as positive in terms of effects on health due to oxidative stress.…”

Section: Exposures Based On Residence Areamentioning

confidence: 99%

“…Bisphenol A (4,4 -(hexafluoroisopropylidene)-diphenol) (BPA) is an important monomer in the production of polycarbonate and epoxy plastics, but it is also used in various other applications. In polyvinylchloride (PVC) plastic, BPA acts as an antioxidant [1]. Due to its high production volume and migration from plastics, human exposure to BPA is widespread.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bisphenols and Oxidative Stress Biomarkers—Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers

Steffensen

Dirven

Couderq

et al. 2020

IJERPH

View full text Add to dashboard Cite

Bisphenols, particularly bisphenol A (4,4′-(hexafluoroisopropylidene)-diphenol) (BPA), are suspected of inducing oxidative stress in humans, which may be associated with adverse health outcomes. We investigated the associations between exposure to bisphenols and biomarkers of oxidative stress in human studies over the last 12 years (2008‒2019) related to six health endpoints and evaluated their suitability as effect biomarkers. PubMed database searches identified 27 relevant articles that were used for data extraction. In all studies, BPA exposure was reported, whereas some studies also reported other bisphenols. More than a dozen different biomarkers were measured. The most frequently measured biomarkers were 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-OHdG), 8-iso-prostaglandin F2α (8-isoprostane) and malondialdehyde (MDA), which almost always were positively associated with BPA. Methodological issues were reported for MDA, mainly the need to handle samples with caution to avoid artefact formation and its measurements using a chromatographic step to distinguish it from similar aldehydes, making some of the MDA results less reliable. Urinary 8-OHdG and 8-isoprostane can be considered the most reliable biomarkers of oxidative stress associated with BPA exposure. Although none of the biomarkers are considered BPA- or organ-specific, the biomarkers can be assessed repeatedly and non-invasively in urine and could help to understand causal relationships.

show abstract

Section: Exposures Based On Residence Areamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bisphenols and Oxidative Stress Biomarkers—Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers

Steffensen

Dirven

Couderq

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…For example, bisphenol antioxidants are added into flexible PVC to reduce the dehydrochlorination. 13 The mechanisms of action of antioxidants include the trapping of alkyl radicals (e.g. phenylenediamine derivations 14 ), and the degradation of PVC during photo aging is commonly considered to be free radical degradation.…”

Section: Introductionmentioning

confidence: 99%

Combined effect of hindered amine light stabilizer and antioxidants on photodegradation of poly (vinyl chloride)

Chai

Chen

Zhang

2011

Journal of Thermoplastic Composite Materials

View full text Add to dashboard Cite

Casted PVC films with hindered amine light stabilizer (HALS) and antioxidants are photo-irradiated for 400 h and the process of photodegradation is characterized by color differences, ultraviolet-visible (UV-vis) spectroscopy, Fourier transformation infrared (FT-IR) spectroscopy and viscosity-average molecular weight (M ). When added to PVC separately, hindered amine derivate (T770) and phenol antioxidant ( 1076) both have little effect on the dehydrochlorination and oxidation of PVC films. In PVC films with T770/1076, the extension of shorter polyenes is retarded during photo-irradiation of 400 h. The extension of longer polyenes is well retarded from 0 h to 200 h. T770/ 1076 has only a little effect on the anti-oxidation of PVC films from 0 h to 400 h. The p-phenylenediamine antioxidant (4010NA) and 2-Mercapto benzimidazole (MB) both accelerate the photodegradation and crosslinking of PVC films. However, there is no crosslinking in PVC with T770/4010NA and PVC with T770/MB and the degradation of PVC films is weakened. This phenomenon means the light stabilizer T770 protects antioxidants (4010NA and MB) from photo-irradiation and antioxidants can play a positive role in the antioxidative effect.

show abstract

Principles of Stabilization

Wypych¹

2015

PVC Degradation and Stabilization

View full text Add to dashboard Cite

The influence of bisphenol antioxidants on thermo-oxidative degradation of plasticised poly(vinyl chloride)

Cited by 6 publications

References 0 publications

Bisphenols and Oxidative Stress Biomarkers—Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers

Bisphenols and Oxidative Stress Biomarkers—Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers

Combined effect of hindered amine light stabilizer and antioxidants on photodegradation of poly (vinyl chloride)

Principles of Stabilization

Contact Info

Product

Resources

About