The influence of amoeba metal homeostasis on antifungal activity against Cryptococcus gattii
Maria Eduarda Deluca João,
Andrea Gomes Tavanti,
Alexandre Nascimento de Vargas
et al.
Abstract:Free-living amoebas are natural predators of fungi, including human pathogens of
the
Cryptococcus
genus. To survive and proliferate inside
phagocytes, cryptococcal cells must acquire several nutrients. Zinc is
fundamental for all life forms and develops a crucial role in the virulence of
fungal pathogens, phagocytes reduce the availability of this metal to reduce the
development of infection. The
Acanthamoeba castellanii
ACA1
_
271600
gene co… Show more
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