The influence of age and gender on triclosan concentrations in Australian human blood serum

4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels

“…Meanwhile, 4-NP, BPA and TCS have already been detected in human urine, blood and breast milk of some countries (Ademollo et al, 2008;Allmyr et al, 2006Allmyr et al, , 2008Calafat et al, 2008a,b;Inoue et al, 2000Inoue et al, , 2003Vandenberg et al, 2007); and BPA was even found in amniotic fluid, follicular fluid, placental tissue, semen, umbilical cord blood, fetal serum and adipose tissues (Vandenberg et al, 2007;Vandenberg et al, 2010).…”

Crystal Structure of the Human Fatty Acid Synthase Enoyl-Acyl Carrier Protein-Reductase Domain Complexed with Triclosan Reveals Allosteric Protein-Protein Interface Inhibition

“…26). It is a common antibacterial agent in personal care products, and studies have revealed that it can be detected in urine, semen, and breast milk (27)(28)(29)(30)(31)(32)(33), although there is no evidence of accumulation in animal models or humans (27). A number of studies implicate it in estrogenpositive tumor cell proliferation because of its xenoestrogenic properties (34 -36); however, several more studies indicate that it is selectively cytotoxic to tumor cells and could even reduce tumor incidence in vivo (36 -41).…”

Elevation of Intracellular Ca2+ Level by Triclosan in Rat Thymic Lymphocytes: Increase in Membrane Ca2+ Permeability and Induction of Intracellular Ca2+ Release

“…[6][7][8] This agent is also found in the bodies of wild animals as well as humans, 9,10) including maternal milk 3,11) and blood. 12) Triclosan concentrations in blood plasma of human mothers were in the range of 0.4-38 µg/l. 3) Because human plasma concentrations of triclosan seem to be submicromolar (< 0.131 µM), it is unlikely that it affects the intracellular Ca 2+ concentration of the cells present in the bloodstream.…”