The influence of acetaminophen on repeated sprint cycling performance

Foster, Josh; Taylor, Lee; Chrismas, Bryna C. R.; Watkins, S. L.; Mauger, Alexis R.

doi:10.1007/s00421-013-2746-0

Cited by 55 publications

(95 citation statements)

References 42 publications

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“…For instance, previous research has shown that paracetamol improves performance in a 10-mile cycling time trial compared to placebo in the absence of a reduction in perceived pain or perceived exertion 3 . In another study, Foster et al 25 , also found that paracetamol improved performance compared to placebo.…”

Section: Discussionmentioning

confidence: 91%

Tramadol effects on physical performance and sustained attention during a 20-min indoor cycling time-trial: A randomised controlled trial

Holgado

Zandonai

Zabala

et al. 2018

Journal of Science and Medicine in Sport

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Objectives: To investigate the effect of tramadol on performance during a 20-min cycling time-trial (Experiment 1), and to test whether sustained attention would be impaired during cycling after tramadol intake (Experiment 2).Design: randomized, double-blind, placebo controlled trial. Methods:In Experiment 1, participants completed a cycling time-trial, 120-min after they ingested either tramadol or placebo. In Experiment 2, participants performed a visual Oddball task during the time-trial.Electroencephalography measures (EEG) were recorded throughout the session. Results:In Experiment 1, average time-trial power output was higher in the tramadol vs. placebo condition (tramadol: 220 watts vs. placebo: 209 watts; p < 0.01). In Experiment 2, no differences between conditions were observed in the average power output (tramadol: 234 watts vs. placebo: 230 watts; p > 0.05). No behavioural differences were found between conditions in the Oddball task. Crucially, the time frequency analysis in Experiment 2 revealed an overall lower target-locked power in the beta-band (p < 0.01), and higher alpha suppression (p < 0.01) in the tramadol vs. placebo condition. At baseline, EEG power spectrum was higher under tramadol than under placebo in Experiment 1 while the reverse was true for Experiment 2. Conclusions:Tramadol improved cycling power output in Experiment 1, but not in Experiment 2, which may be due to the simultaneous performance of a cognitive task. Interestingly enough, the EEG data in Experiment 2 pointed to an impact of tramadol on stimulus processing related to sustained attention. Trial registration:EudraCT number: 2015-005056-96.

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Section: Discussionmentioning

confidence: 91%

Tramadol effects on physical performance and sustained attention during a 20-min indoor cycling time-trial: A randomised controlled trial

Holgado

Zandonai

Zabala

et al. 2018

Journal of Science and Medicine in Sport

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“…Changes in work rate are made so as to moderate the level of pain and discomfort perceived, with reductions in work rate to manage the increase in pain, and increases in work rate to increase pain to a level that the athlete is willing to endure. These suggestions are supported by work that has used analgesia during self-paced exercise to improve performance 24,41. In these studies, cyclists appear to exercise according to a set progression of pain, with changes in work rate used to maintain this.…”

Section: Perspectivesmentioning

confidence: 94%

“…Consequently, moderate levels of induced pain may have little effect on short-duration or short-term voluntary contraction exercise, but elicit a large effect in long-duration exercise. Indeed, the effect of inducing experimental pain on short-duration exercise has produced equivocal results,46–49 whereas in exercise that lasts for long periods, increased or decreased pain frequently worsens or improves endurance performance, respectively 24,41,45. The difficulties associated with testing the exercise-induced pain hypothesis (ie, by experimentally increasing or decreasing pain) may contribute towards these differing findings.…”

Section: Perspectivesmentioning

confidence: 99%

“…Additionally, untrained individuals may have less willingness to engage in an exercise intensity that elicits pain and be more likely to cease exercise as a result of pain. Interventions that reduce the magnitude of pain perception during exercise will allow the athlete to maintain a higher work rate during the exercise and consequently improve their performance 24,41. This effect may be stronger in lesser trained athletes as their physiological reserve will likely be more conservative than highly trained athletes.…”

Section: Perspectivesmentioning

confidence: 99%

See 1 more Smart Citation

Factors affecting the regulation of pacing: current perspectives

Mauger¹

2014

OAJSM

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During prolonged dynamic and rhythmic exercise, muscular pain and discomfort arises as a result of an increased concentration of deleterious metabolites. Sensed by peripheral nociceptors and transmitted via afferent feedback to the brain, this provides important information regarding the physiological state of the muscle. These sensations ultimately contribute to what is termed “exercise-induced pain”. Despite being well recognized by athletes and coaches, and suggested to be integral to exercise performance, this construct has largely escaped attention in experimental work. This perspective article highlights the current understanding of pacing in endurance performance, and the causes of exercise-induced pain. A new perspective is described, which proposes how exercise-induced pain may be a contributing factor in helping individuals to regulate their work rate during exercise and thus provides an important construct in pacing.

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“…Small, unblinded studies typically involving non-elite subjects have suggested that paracetamol can improve time to exhaustion260 or decrease perceived exertion in a graded run 261 262. NSAIDs have no effect on sprinting,263 vertical jumping or endurance running performance but can decrease soreness 2 263–265. Opioids can decrease pain265 and increase anaerobic performance265 but not overall physical performance after muscle damage 265.…”

Section: Antidoping Issues In Pain Managementmentioning

confidence: 99%

International Olympic Committee consensus statement on pain management in elite athletes

et al. 2017

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Pain is a common problem among elite athletes and is frequently associated with sport injury. Both pain and injury interfere with the performance of elite athletes. There are currently no evidence-based or consensusbased guidelines for the management of pain in elite athletes. Typically, pain management consists of the provision of analgesics, rest and physical therapy. More appropriately, a treatment strategy should address all contributors to pain including underlying pathophysiology, biomechanical abnormalities and psychosocial issues, and should employ therapies providing optimal benefit and minimal harm. To advance the development of a more standardised, evidenceinformed approach to pain management in elite athletes, an IOC Consensus Group critically evaluated the current state of the science and practice of pain management in sport and prepared recommendations for a more unified approach to this important topic.

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The influence of acetaminophen on repeated sprint cycling performance

Cited by 55 publications

References 42 publications

Tramadol effects on physical performance and sustained attention during a 20-min indoor cycling time-trial: A randomised controlled trial

Tramadol effects on physical performance and sustained attention during a 20-min indoor cycling time-trial: A randomised controlled trial

Factors affecting the regulation of pacing: current perspectives

International Olympic Committee consensus statement on pain management in elite athletes

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