The influence of a sustained multifaceted approach to improve antibiotic prescribing in Slovenia during the past decade: findings and implications

Fürst, Jurij; Čižman, Milan; Mrak, Jana; Kos, Damjan; Campbell, Stephen; Coenen, Samuel; Gustafsson, Lars L.; Fürst, Luka; Godman, Brian

doi:10.1586/14787210.2015.990381

Cited by 74 publications

(107 citation statements)

References 39 publications

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“…In many instances, multiple interventions may have to be deployed to drive the necessary changes. Of note, again, is the fact that efforts to promote rational medicine/prescribing should be multifaceted in nature, and must also target aspects of patient and community behaviour [70,71]. …”

Section: Strategies To Tackle Irrational Prescribingmentioning

confidence: 99%

Irrational Use of Medicines—A Summary of Key Concepts

Ofori‐Asenso¹,

Agyeman²

2016

Pharmacy

208

201

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Medicines play an integral part of healthcare delivery. However, they are expensive commodities and account for a significant proportion of overall health expenditure in most countries. Irrational use of medicines is a major challenge facing many health systems across the world. Such practices are likely to lead to poor health delivery that may put patients at risk and result in wastage of scarce resources that could have been used to tackle other pressing health needs. The concept of “rational use of medicine” can at times be confusing and not easily appreciated by patients, healthcare providers, policy makers, or the public, all of whom need to collaborate effectively to address this challenge. In this article, we summarize basic concepts such as rational medicine use, good prescribing and dispensing, and explore some of the factors that contribute to irrational use of medicines as well as potential impacts of such practices. This article has been written with the intention of offering a clear, concise, and easy to understand explanation of basic medicine use concepts for health professionals, patients, policy makers, and the public.

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Section: Strategies To Tackle Irrational Prescribingmentioning

confidence: 99%

Irrational Use of Medicines—A Summary of Key Concepts

Ofori‐Asenso¹,

Agyeman²

2016

Pharmacy

208

201

View full text Add to dashboard Cite

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“…Successful multifaceted approaches instigated in Slovenia to reduce antibiotic utilization involved extensive educational programs, QIs and prescribing restrictions [19]. There are also ongoing programs to reduce polypharmacy [16] involving QIs and pharmacotherapy groups.…”

mentioning

confidence: 99%

Improving the managed introduction of new medicines: sharing experiences to aid authorities across Europe

Matusewicz¹,

Godman

Pedersen

et al. 2015

Expert Review of Pharmacoeconomics & Outcomes Research

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“…Antimicrobial resistance [2] is one of the most critical problems threatening healthcare systems, currently causing the deaths of several hundred thousand patients worldwide and forcing countries to investigate effective countermeasures [3][4][5]. Patient-specific side effects such as diarrhea and Clostridium difficile infections can be reduced by limiting antibiotic exposure.…”

mentioning

confidence: 99%

Management of patients with respiratory infections in primary care: procalcitonin, C-reactive protein or both?

Meili

Müller

Kulkarni³

et al. 2015

Expert Review of Respiratory Medicine

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Use of inflammatory biomarkers to guide antibiotic decisions has shown promising results in the risk-adapted management of respiratory tract infections, mainly in the inpatient setting. Several observational and interventional trials have investigated the benefits of procalcitonin (PCT) and C-reactive protein (CRP) testing in primary care. Both markers have shown promising results, although CRP is an inflammatory biomarker while PCT is more specific for bacterial infections. For CRP, point-of-care testing is widely established. Recently, sensitive point-of-care testing for PCT has also become available. A high-quality trial comparing these two markers for the management of patients in primary care is currently lacking. The aim of this paper is to review the existing literature investigating the use of PCT and CRP in primary care. The authors compare their performance for guiding antibiotic stewardship and analyze the cut-off values and endpoints to put these parameters into context in a low-acuity environment.

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The influence of a sustained multifaceted approach to improve antibiotic prescribing in Slovenia during the past decade: findings and implications

Cited by 74 publications

References 39 publications

Irrational Use of Medicines—A Summary of Key Concepts

Irrational Use of Medicines—A Summary of Key Concepts

Improving the managed introduction of new medicines: sharing experiences to aid authorities across Europe

Management of patients with respiratory infections in primary care: procalcitonin, C-reactive protein or both?

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