The Indications for Minimally Invasive Glaucoma Surgery, Trabeculectomy, Tube Shunts, and Cyclophotocoagulation in Glaucoma Surgery

Islam, Yasmin; Sherwood, Mark B.; Blake, Charles Richard

doi:10.1016/j.yaoo.2020.05.003

Cited by 3 publications

(1 citation statement)

References 46 publications

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“…If two of the above treatments fail, surgery may be considered to reduce the lower IOP. Various surgical options include glaucoma filtration surgery (trabeculectomy), glaucoma tube surgeries, and more recent minimally invasive glaucoma surgeries (MIGS) [ 29 , 30 , 31 , 32 ]. Filtration surgery creates a channel through which the aqueous humor can be drained through bleb formation [ 22 , 30 , 33 ].…”

Section: Glaucoma Treatmentmentioning

confidence: 99%

Novel Drug Delivery Systems Fighting Glaucoma: Formulation Obstacles and Solutions

et al. 2020

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Glaucoma is considered to be one of the biggest health problems in the world. It is the main cause of preventable blindness due to its asymptomatic nature in the early stages on the one hand and patients’ non-adherence on the other. There are several approaches in glaucoma treatment, whereby this has to be individually designed for each patient. The first-line treatment is medication therapy. However, taking into account numerous disadvantages of conventional ophthalmic dosage forms, intensive work has been carried out on the development of novel drug delivery systems for glaucoma. This review aims to provide an overview of formulation solutions and strategies in the development of in situ gel systems, nanosystems, ocular inserts, contact lenses, collagen corneal shields, ocular implants, microneedles, and iontophoretic devices. The results of studies confirming the effectiveness of the aforementioned drug delivery systems were also briefly presented.

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