The increasing role of abdominal metastesectomy for malignant melanoma in the era of modern therapeutics

Mor, Eyal; Assaf, Dan; Asher, Nethanel; Ben‐Betzalel, Guy; Grynberg, Shirly; Stoff, Ronen; Adileh, Mohammad; Steinberg‐Silman, Yael; Schachter, Jacob; Nissan, Aviram; Zippel, Douglas

doi:10.1016/j.suronc.2022.101808

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The Role Of Metastectomy In Melanoma1

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2024

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“…Metastasectomy may serve as an adjunct to systemic treatment in these patients. In addition, the increased use of minimally invasive techniques has decreased morbidity and improved patient outcomes associated with surgery [ 74 , 75 , 76 ]. A single site of metastasis and a long DFI before metastasis are also associated with better outcomes [ 74 , 77 , 78 ].…”

Section: The Role Of Metastectomy In Melanomamentioning

confidence: 99%

Role of Surgery in Metastatic Melanoma and Review of Melanoma Molecular Characteristics

Sukniam,

Manaise,

Popp

et al. 2024

Cells

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We aimed to review the molecular characteristics of metastatic melanoma and the role of surgery in metastasectomy for metastatic melanoma. We performed a systematic literature search on PubMed to identify relevant studies focusing on several mutations, including NRAS, BRAF, NF1, MITF, PTEN, TP53, CDKN2A, TERT, TMB, EGFR, and c-KIT. This was performed in the context of metastatic melanoma and the role of metastasectomy in the metastatic melanoma population. A comprehensive review of these molecular characteristics is presented with a focus on their prognosis and role in surgical metastasectomy.

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