The Increased Risk of Thromboembolic Events in Patients with Rheumatoid Arthritis

González, Raquel; Juanola, Jordi; Tirado, Concepción Falga; Marmol, Carlos Lopera; M, Castillo; Ruzafa, Ana Lafont

doi:10.3899/jrheum.190899

Cited by 3 publications

(5 citation statements)

References 7 publications

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“…This case is worthy of being reported because there is said to be a lack of awareness of the relationship between RA and increased risk of DVT [1,2], and this assertion would appear to be supported by this patient's experience at the minor injuries unit. To miss the diagnosis of VTE is potentially fatal; clinicians must keep in mind the possibility of a DVT with every patient who presents with posterior leg pain.…”

Section: Discussionmentioning

confidence: 74%

“…Rheumatoid arthritis (RA) is a common, chronic, and systemic inflammatory autoimmune disease; patients with RA have significant associated morbidity and shorter life expectancy than the healthy population [1]. Although RA primarily targets the synovial lining of the joints, it also has adverse extra-articular effects, including those affecting the pulmonary, cardiac, and vascular systems, which are said to contribute to shortened life expectancy [2].…”

Section: Introductionmentioning

confidence: 99%

“…There is said to be a paucity of data regarding the risks of RA-related deep vein thrombosis (DVT) or pulmonary embolism (PE) compared with the volume of research investigating the adverse effects of RA on the arterial system, such as myocardial infarction (MI) and stroke. There is also said to be less awareness of DVT and PE risk in RA among some practitioners [1,2], even though this has been widely reported [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…PE is the third most common cardiovascular (CV) risk behind MI and stroke. There is a 15% fatality rate [1]; therefore, it is of vital importance to be aware of the increased venous thromboembolism (VTE) risk in RA, particularly when patients present with calf discomfort or any other symptoms that could implicate the CV system.…”

Section: Introductionmentioning

confidence: 99%

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Patient with rheumatoid arthritis with deep vein thrombosis presenting as a calf strain: a case report

Lewis

2020

J Med Case Reports

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Background Patients with rheumatoid arthritis experience various comorbidities, including cardiovascular disease. More data and awareness exist regarding the adverse effects of rheumatoid arthritis affecting the arterial side of the cardiovascular system, such as stroke or myocardial infarction, than regarding adverse venous complications, such as deep vein thrombosis and pulmonary embolism. Rheumatoid arthritis affects more women than men, and the risk of venous thromboembolism in rheumatoid arthritis tends to increase with age; therefore, the presentation in this case report of deep vein thrombosis in a nonsmoking, young, fit man with rheumatoid arthritis is rare. This patient was sent away from a minor injuries unit with a diagnosis of a calf strain. Further assessment at an accident and emergency department later in the day confirmed deep vein thrombosis via ultrasonography. This case report underlines the need for vigilance because deep vein thrombosis is a risk factor in rheumatoid arthritis, even in young, male, and physically fit individuals. Case presentation A nonsmoking 39-year-old Caucasian man with a 2-year history of rheumatoid arthritis presented for assessment at a private physiotherapy clinic with a 4-week history of right-sided posterior calf pain that had developed following exercise at a gym. The patient therefore believed his symptoms were due to a calf strain. Findings at physiotherapy assessment suggested that the actual cause of the patient’s symptoms were as a result of deep vein thrombosis. The patient was directed to a local minor injuries unit with a referral letter from the author outlining this diagnosis. Following clinical assessment at the minor injuries unit, the patient was told that there was no likelihood of deep vein thrombosis, and his diagnosis was a calf strain. The patient harbored concerns at this point and decided to seek further medical opinion at a nearby accident and emergency department, where deep vein thrombosis was diagnosed using ultrasonography, and the patient was commenced on anticoagulants. Conclusions Venous thromboembolism risk in rheumatoid arthritis is stated as being less recognized as an arterial complication. This is borne out by this patient’s clinical journey, wherein his youth, fitness, athletic appearance, and onset of symptoms during exercise were said to suggest a diagnosis of a calf strain at a minor injuries unit. Ultrasonography at a different accident and emergency unit later that day ultimately was used to diagnose deep vein thrombosis.

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Section: Discussionmentioning

confidence: 74%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Patient with rheumatoid arthritis with deep vein thrombosis presenting as a calf strain: a case report

Lewis

2020

J Med Case Reports

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“…Romatizmal yakınmalarla hekime başvuran hastaların; %55-60'unu yumuşak dokudan kaynaklanan romatizmal problemler, %30-38'ini dejeneratif eklem hastalıkları, %10 kadarını da romatoid artrit gibi inflamatuar orjinli hastalıklar oluşturmaktadır. Özellikle romatoid artrit tanısı almış hastalarda PE'nin sık görüldüğüne dair araştırmalar mevcuttur (6) .…”

Section: Introductionunclassified

Relation between Rheumatological Diseases and MPV Levels with Pulmonary Embolism

Tabur¹

2020

IGH

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INTRODUCTION: Pulmonary Embolism (PE) is shown as an important health problem all over the world. Many predisposed conditions are known, which are the cause of PE. There are an acquired and genetic risk factors for PE, but in 30% of patients the cause cannot be determined. There are so many and genetic risk factors for PE. However, in %30 of patients the cause aren’t determined. New risk factors are being investigated in recent years. In this study, the relationship between PE and the value of mid platelet volume (MPV) and rheumatological diseases (RH) was studied. METHODS: The records in the hospital database were used in the study. Patients diagnosed with PE between January 2008 and July 2012 were determined retrospectively and 64 patients were included in the study. Among patients diagnosed with PE, those diagnosed with RH and average MPV values of patients were determined. A control group was formed by selecting 64 patients who were not diagnosed with PE and RH from the patients who applied at the same time interval with the case group.Among the patients with PE and who are diagnosed with the RD and whose values of MPV were determined. PE patiends and Rheumatologic patients who are diagnosed with PE and whose values of MPV were compared. RESULTS: As a result of the analyzes, it was determined that there was no significant difference between the case and control groups.

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The Spectrum of Airway Involvement in Inflammatory Bowel Disease

Camus

Colby

2022

Clinics in Chest Medicine

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The Increased Risk of Thromboembolic Events in Patients with Rheumatoid Arthritis

Abstract: patients described signed written informed consent to publish the material.

Cited by 3 publications

References 7 publications

Patient with rheumatoid arthritis with deep vein thrombosis presenting as a calf strain: a case report

Patient with rheumatoid arthritis with deep vein thrombosis presenting as a calf strain: a case report

Relation between Rheumatological Diseases and MPV Levels with Pulmonary Embolism

The Spectrum of Airway Involvement in Inflammatory Bowel Disease

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