The Increase of Osteoporotic Hip Fractures and Associated One-Year Mortality in Poland: 2008–2015

Glinkowski, Wojciech; Narloch, Jerzy; Krasuski, Krzysztof; Śliwczyński, Andrzej

doi:10.3390/jcm8091487

Cited by 24 publications

(24 citation statements)

References 48 publications

(78 reference statements)

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“…In addition, indicators of osteoporosis such as bone density or imaging information are seldom available in the medical insurance databases. Therefore, consistent with previous publications on hip fracture incidence [8,9,11,16,29], in this study, hip-fracture-related indicators such as the incidence of hip fracture and associated costs in patients aged 55 years and above were used as surrogate indexes for determining the burden of osteoporosis or osteoporotic fractures. The inclusion criteria of the population were individuals who (1) had either UEMBI or URBMI during 2012 to 2016, (2) were enrolled in UEMBI or URBMI in 1 of the 23 provinces included in the study, and (3) were �55 years old at the first hip fracture during the study period.…”

Section: Study Populationmentioning

confidence: 82%

Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study

et al. 2020

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Background Hip fracture is a public health concern because of its considerable morbidity, excess mortality, great risk of disability, and high societal healthcare costs. China has the largest population of older people in the world and is experiencing rapid population aging and facing great challenges from an increasing number of hip fractures. However, few studies reported the epidemiology, especially at a national level. We aimed to evaluate trends in hip fracture incidence and associated costs for hospitalization in China. Methods and findings We conducted a population-based study using data between 2012 and 2016 from the national databases of Urban Employee Basic Medical Insurance and Urban Resident Basic Medical Insurance in China, covering about 480 million residents. Data from around 102.56 million participants aged 55 years and older during the study period were analyzed. A total of 190,560 incident hip fracture patients (mean age 77.05 years, standard deviation 8.94; 63.99% female) were identified. Primary outcomes included the age-and sex-specific incidences of hip fracture. Associated annual costs for hospitalization were also calculated. Incidence was described as per 100,000 person-years at risk, and 95% confidence intervals were computed assuming a Poisson distribution. Hip fracture incidence overall in China did not increase during the study period despite rapid population aging. Incidence per 100,000

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Section: Study Populationmentioning

confidence: 82%

Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study

et al. 2020

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“…suggested that hip fracture rates may be increasing in Poland [3], France [4], Japan [5], Italy [6], and China [7].…”

Section: Introductionmentioning

confidence: 99%

High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture

Wang¹,

Wang²,

Yang³

et al. 2020

International Orthopaedics (SICOT)

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Purpose The platelet-to-lymphocyte ratio (PLR) has been extensively studied in various diseases. However, the relationship between PLR and hip fracture remains unknown. The aim of this study was to evaluate whether PLR would be an independent prognostic factor in elderly hip fracture patients. Methods Between January 2014 and December 2018, a retrospective cohort study was conducted in a orthopaedic centre, China. A total of 460 hip fracture patients were included. PLR was calculated as the ratio of platelet to lymphocyte counts and divided into high PLR group (≥ 189) and low PLR group (< 189) by using the receiver operating characteristic (ROC) curve. The relationship between PLR and one year all-cause mortality rate was assessed by univariate and multivariate Cox proportional hazard models. Further subgroup analysis stratified by different clinical and biological characteristics was performed to make the results more accurate. Results After a median follow-up of 32.0 months (range, 12.0-75.4), 92 patients (mortality rate: 20.0%) died within one year. PLR was significantly higher in dead patients compared with alive patients (p < 0.05), and high PLR group also had a high mortality rate (32.21% vs. 14.15%, p < 0.001). After multivariate adjustment, high PLR remained an independent predictor for one year all-cause mortality (adjusted hazard ratio (HR) 1.56, 95% confidence interval (CI) 1.02-2.41, p = 0.041). Moreover, advanced age (HR 1.05, 95% CI 1.01-1.08), male (HR 1.62, 95% CI 1.06-2.45), CCI ≥ 2 (HR 2.83, 95% CI 1.64-4.89), conservative treatment (HR 5.94, 95% CI 3.71-9.73), low haemoglobin level (HR 1.02, 95% CI 1.01-1.04), and low albumin level (HR 1.07, 95% CI 1.02-1.13) were independent risk factors for survival. Furthermore, subgroup analysis results were consistent with the main findings in most stratified groups. Conclusion This study highlights that high PLR (≥ 189) is associated with increased one year all-cause mortality in elderly hip fracture patients. As PLR is a simple indicator that can be calculated from the blood routine test, it can be easily performed in usual clinical practice.

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“…In Brazil, studies show a variation of the mortality rate ranging from 2.8% in elderly people with multiple injuries in Curitiba (State of Paraná) [3] to 28.7% in the elderly people with hip fractures in Porto Alegre (State of Rio Grande do Sul) [18]. Studies worldwide report a mortality rate of 37.2% in hospitalized elderly patients with hip fractures in Turkey [4], 30% in Poland [19], 11.4% in Spain [20], and 12.3% in elderly with axis fractures in USA [21]. Wide variation can be attributed to the diversity of the populations and the fractures admitted to hospitals and probably reflects the different standards of care provided at these institutions.…”

Section: Discussionmentioning

confidence: 99%

Survival Analysis of Hospitalized Elderly People with Fractures in Brazil Over One Year

et al. 2020

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Objective: This study analyzes the causes of death, survival, and other related factors in hospitalized elderly people with fractures over the course of one year. Methods: We followed 376 fracture patients for one year in a prospective cohort study to a reference hospital in central Brazil. The Cox regression model was used to analyze factors associated with survival. Results: The results indicate that the one-year mortality rate was high (22.9%). The independent factors linked to lower overall survival were as follows: patients aged ≥80 years with previous intensive care unit (ICU) admission and presence of comorbidities (diabetes mellitus [DM] and dementia). Conclusion: Our study results may contribute to a better understanding of the impact of fractures on the elderly population and reinforce the need to oversee age-groups, diabetic patients, and patients with complications during hospitalization.

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The Increase of Osteoporotic Hip Fractures and Associated One-Year Mortality in Poland: 2008–2015

Cited by 24 publications

References 48 publications

Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study

Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study

High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture

Survival Analysis of Hospitalized Elderly People with Fractures in Brazil Over One Year

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