The Incidence Rate and Economic Burden of Catheter-related Bloodstream Infection (CRBSI): a Single center, Retrospective Study

Abstract

BackgroundIndwelling central venous catheters (CVCs) have the potential to lead to catheter related blood stream infection (CRBSI). We report the findings of a single center, retrospective matched case-control study that assessed the incidence rate of CRBSI in ICUs and attributable length of stay (LOS), costs among patients with CRBSI in ICU in Shanghai, China.MethodsThe study was carried out in several ICUs, with a total of 2300 beds of 3 tertiary-level hospital affiliated to Shanghai Jiao Tong University. The Department of Infection Control performs routinely surveillance for CRBSI on ten different ICUs.ResultsThe CRBSI incidence rate of hematology ICU, which was the highest, was 4.43 per 1000 CVC-days. 51 patients were successfully matched with control patients. The average cost in the CRBSI group was $ 67,923 which was significantly higher (P < 0.001) than that in the control group. The total average cost attributable to CRBSI was $33, 227.ConclusionsThe cost of antibiotics was closely related to the incidence of CRBSI.