The incidence, operative difficulty and outcomes of staged versus index admission laparoscopic cholecystectomy and bile duct exploration for all comers: a review of 5750 patients

Abstract

Background The timing of laparoscopic cholecystectomy (LC) for emergency biliary admissions remains inconsistent with national and international guidelines. The perception that LC is difficult in acute cholecystitis and the popularity of the two-session approach to pancreatitis and suspected choledocholithiasis result in delayed management. Methods Analysis of prospectively maintained data in a unit adopting a policy of “intention to treat” during the index admission. The aim was to study the incidence of previous biliary admissions and compare the operative difficulty, complications and postoperative outcomes with patients who underwent index admission LC. Results Of the 5750 LC performed, 20.8% had previous biliary episodes resulting in one admission in 93% and two or more in 7%. Most presented with biliary colic (39.6%) and acute cholecystitis (27.6%). A previous biliary history was associated with increased operative difficulty (p < 0.001), longer operating times (86.9 vs. 68.1 min, p < 0.001), more postoperative complications (7.8% vs. 5.4%, p = 0.002) and longer hospital stay (8.1 vs. 5.5 days, p < 0.001) and presentation to resolution intervals. However, conversion and mortality rates showed no significant differences. Conclusion Index admission LC is superior to interval cholecystectomy and should be offered to all patients fit for general anaesthesia regardless of the presenting complaints. Subspecialisation should be encouraged as a major factor in optimising resource utilisation and postoperative outcomes of biliary emergencies.

Relationship between postoperative biliary stricture and clinical characteristics of patients with benign and malignant biliary diseases.

“…Biliary stones are the most common benign diseases. According to the National Institute for Health and Care Excellence (NICE) consensus in 2016, 10–15% of British adults suffer from gallbladder stones and/or bile duct stones, 50% of symptomatic patients will have recurrent abdominal pain, fever, jaundice and other symptoms, and 1–2% of patients will have serious complications [ 15 ]. Cholangiocarcinoma is the most common malignant disease, originating from biliary epithelial cells.…”