“…As expected, studies using active surveillance methods exhibited relatively higher incidence rates, which ranged from 8 to 51/100 000 (median 22; interquartile range 10–23/100 000), compared with those employing passive surveillance with lower incidence rates of 5–35/100 000 (median 16; interquartile range 5–18/100 000). Crude incidence rates and age-adjusted rates derived from studies from the USA,12 Chile,13 Martinique and Gouadaloupe,14 and Sweden16 showed a low ARF incidence of ⩽10/100 000 per year; while those from Eastern Europe,15 Middle East,17 – 19 Asia,20 and Australasia21 had a higher incidence >10/100 000 per year. Six of the 10 included studies assessed the incidence of ARF in the first three decades of life,16 – 182021 and the remainder included all age groups 12 – 14 19.…”