The incidence of postoperative endophthalmitis after cataract surgery in China: a multicenter investigation of 2006–2011

Yao, Ke; Zhu, Yanan; Zhu, Zhihong; Wu, Jianjun; Liu, Yizhi; Lü, Yi; Hao, Yansheng; Bao, Yongzhen; Ye, Jian; Huang, Yusen; Li, Zhaohui; Shentu, Xingchao; Yu, Yi

doi:10.1136/bjophthalmol-2013-303282

Cited by 48 publications

(54 citation statements)

References 28 publications

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“…Confusingly, recent studies have proposed that the incidence of postoperative endophthalmitis was not related to the incision location723. Here, in our study, we observed no relationship between the type of incision and the development of endophthalmitis (p = 0.718).…”

Section: Discussioncontrasting

confidence: 61%

“…We found that the ECCE surgery rate was much higher in the small and medium-scale departments when compared with the top eye centers in China (10.3% vs 2.2%)2. The low coverage of phacoemulsification suggests an imbalance of medical resources in China, including the lesser skills of the surgeons and the lack of proper equipment in most Chinese hospitals.…”

Section: Discussionmentioning

confidence: 79%

“…In a previous study published in the British Journal of Ophthalmology on July 24, 2013, we focused on top eye centers (cataract surgery volume ≥150 cases per month), which represent the most advanced medical care environment in China. We investigated the occurrence rate of acute-onset endophthalmitis after 201,757 cataract surgeries in eight centers between 2006 and 2011 (0.033%), which was close to that reported in developed countries2. Obviously, that study could not determine the overall status of the postoperative endophthalmitis incidence and treatment throughout the whole country.…”

mentioning

confidence: 64%

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The occurrence rate of acute-onset postoperative endophthalmitis after cataract surgery in Chinese small- and medium-scale departments of ophthalmology

Zhu

Chen

et al. 2017

Sci Rep

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Endophthalmitis can be a devastating complication after cataract surgery. Therefore, this study sought to better understand the occurrence rate of acute-onset postoperative endophthalmitis after cataract surgery in Chinese small and medium-scale departments of ophthalmology, as well as identify its risk factors and assess the treatment options. This investigation revealed 52 postoperative endophthalmitis cases in 46,185 operations at 30 hospitals from 2011 to 2013, at an occurrence rate of 0.11%. A small cataract surgery volume of less than 500 cases per year (OR 2.21; p = 0.006), the absence of 0.5% povidone iodine (PVP-I) irrigation (OR 1.73; p = 0.046), and intraoperative posterior capsular rupture (PCR) with vitreous loss (OR 4.40; p = 0.034) showed statistically significant associations with endophthalmitis in the multivariate analysis. The rate of culture positivity was 44.2%, with Staphylococcus epidermidis being the most common organism isolated in China. More than 40% of the endophthalmitis cases were treated with a nonstandard antibiotics regimen, and only 32.7% of these had a visual acuity of better than 20/40. We concluded that the occurrence rate of acute-onset endophthalmitis following cataract surgery in Chinese small and medium-scale departments of ophthalmology lags behind the level of developed countries, as well as Chinese top eye centers. Overall, the use of 0.5% PVP-I irrigation seemed to be an effective measure to reduce the risk of the development of postoperative endophthalmitis.

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Section: Discussioncontrasting

confidence: 61%

Section: Discussionmentioning

confidence: 79%

mentioning

confidence: 64%

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The occurrence rate of acute-onset postoperative endophthalmitis after cataract surgery in Chinese small- and medium-scale departments of ophthalmology

Zhu

Chen

et al. 2017

Sci Rep

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“…A multicenter study reported that the incidence of postoperative endophthalmitis was significantly lower in cataract centers that used tobramycin as a prophylaxis against infection. 22 None of the previous studies on the incidence of endophthalmitis specifically analyzed the impact of using disposable adhesive drapes during ophthalmic operations. A systematic review 23 concluded that there was no evidence that disposable adhesive drapes could reduce surgical site infection rates.…”

Section: Discussionmentioning

confidence: 99%

The Incidence of Postoperative Endophthalmitis Before and After a Revised Preoperative Surgical Site Preparation Protocol

Kwok

Yip²,

Jhanji³

et al. 2016

Asia-Pacific Journal of Ophthalmology

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“…Olgularımızda endoftalminin %0.046 gibi düşük oranda görülmesinde bu uygulamanın önemli bir rolü olduğu düşüncesindeyiz. Katarakt ameliyatların-dan sonra endoftalmi sıklığı %0.033-0.043 olarak bildirilmiştir (23,24). Katarakt ameliyatları intravitreal enjeksiyonlara kıyasla göziçinde daha çok cerrahi manipulasyon yapılan uygulamalardır.…”

Section: Discussionunclassified

Intravitreal injections and complications

Demir¹,

Akarsu²,

Güven³

et al. 2015

Sisli Etfal

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Amaç: Yapılan intravitreal enjeksiyonların nedenlerini, kullanılan intravitreal ilaçları ve onların komplikasyon oranlarını sunmak Gereç ve Yöntem: Beş yıllık süre diliminde intravitreal enjeksiyon yapılan hastaların kartları geriye dönük olarak incelendi. İntravitreal enjeksiyonların hangi sebeplerle yapıldığı, hangi etken maddenin verildiği, hastaların yaşı, cinsiyeti ve enjeksiyonların komplikasyonları değerlendirildi. İntravitreal enjeksiyonlar ameliyathane şartlarında topikal anestezi altında %5 povidon iyodin konjonktival alana damlatılıp serum fizyolojikle yıkandıktan sonra 27 Gauge (G) iğne ile üst temporal alanda pars planadan vitreus boşluğuna girilerek yapıldı. Bütün enjeksiyonlardan sonra 4x1 dozunda %0.3 ofloksasin damla 1 hafta boyunca kullanıldı. İntravitreal enjeksiyonlarda bevacizumab 1.25-2.5 mg, ranibizumab 0.5 mg, triamsinolon asetonid yalnız kullanıldığında 4 mg ve bevacizumab ile birlikte kullanıldığında 2 mg dozunda kullanıldı. Bulgular: Bu çalışmaya 962 hasta (514 bayan, 448 erkek) alındı. Yaş ortalaması 65±20.3 (18-89) idi. Diyabetik maküla ödemi (DMÖ) için 574 hasta, yaşa bağlı koroid neovaskularizasyonu için 143 hasta, retinal ven kök tıkanıklığı için 47 hasta, retinal ven dal tıkanıklığı için 107 hasta, proliferatif diyabetik retinopati (DR) yalnız veya eşlik eden intraoküler hemoraji için 83 hasta, santral seröz koroidopati için 5 hasta ve yetişkin viteliform dejenerasyonu için 3 hasta olmak üzere toplam 962 hasta intravitreal enjeksiyon tedavisi almıştı. Beş yıllık süre zarfında 962 hastaya 4318 intravitreal injeksiyon yapılmıştı. İntravitreal enjeksiyon'da kullanılan etken maddelerin isimleri ve kullanılma oranları şöyleydi; bevacizumab (%57), ranibizumab (%17), triamsinolon asetonid (%16) ve triamsinolon asetonid+bevacizumab (%10). Sonuçlar: En sık enjeksiyon nedeni DMÖ ve en sık kullanılan etken madde bevacizumab idi. Gelişen en ciddi komplikasyon endoftalmi olup 2 olguda gelişti. Endoftalmi oranı % 0.046 idi. Bir olguda kendiliğinden açılan vitreus içi hemoraji oluştu. Psödoendoftalmi bir olguda triamsinolon enjeksiyonu sonrasında gelişti. Retina dekolmanı izlenmedi. Anahtar kelimeler: Bevacizumab, endoftalmi, intravitreal enjeksiyon, maküla, ranibizumab, triamsinolon asetonid ABSTRACT: Intravitreal injections and complicationsObjective: To report the indications of intravitreal injections, intravitreal drugs used and their complications rate Material and Method: The charts of patients who received intravitreal injection/s for 5 years period were reviewed retrospectively. Indications for intravitreal injections, which drug was used to intravitreally, age and gender of patients, and complications of intravitreal injections were evaluated. All intravitreal injections were performed under topical anesthesia with instillation of 5% povidone iodine and irrigation with saline solution at upper temporal area through the pars plana using 27 gauge needle in the operating room. Ofloxacin 0.3% drop was used 4x1 in all cases for one week. The amount and generic name of drugs used in intravi...

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The incidence of postoperative endophthalmitis after cataract surgery in China: a multicenter investigation of 2006–2011

Cited by 48 publications

References 28 publications

The occurrence rate of acute-onset postoperative endophthalmitis after cataract surgery in Chinese small- and medium-scale departments of ophthalmology

The occurrence rate of acute-onset postoperative endophthalmitis after cataract surgery in Chinese small- and medium-scale departments of ophthalmology

The Incidence of Postoperative Endophthalmitis Before and After a Revised Preoperative Surgical Site Preparation Protocol

Intravitreal injections and complications

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