The incidence of nausea and vomiting in cancer patients in Greek clinical practice: A longitudinal study

Lavdaniti, Maria; Margari, Nikoletta; Chavela, Aikaterini; Mantzanas, Michalis; Chatzi, Ioanna; Fradelos, Εvangelos C.; Tilaveridis, Ioannis; Tzavelas, George

doi:10.5114/wo.2020.95853

Cited by 1 publication

(1 citation statement)

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“…The FACT-G also calculates a total QOL score by adding the four subscale ratings. This questionnaire was validated in the past for the Greek population [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

Quality of Life in Patients With Tongue Cancer After Surgical Treatment: A 12-Month Prospective Study

Palitzika¹,

Tilaveridis²,

Lavdaniti³

et al. 2022

Cureus

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Aim of the study The project assessed the quality of life in post-operative patients with tongue cancer at three-month intervals in the first year after the operation. Material and methods A longitudinal prospective cohort study was conducted in the oral and maxillofacial department of a large public general hospital in northern Greece. Fifty-six patients out of a total of 156 with oral cancer were chosen for the study, who completed distinct quality-of-life surveys (EORTC QLQ-C30, and QLQ Head & Neck Module FACT-G). Results Tumor size correlated negatively with various EORTC QLQ-C30 scores, such as role functioning (p = 0.004) and cognitive functioning (p = 0.007), in the third evaluation. Tumor size correlated positively with subscale problems such as social eating (p = 0.001) and weight loss (p = 0.004) in the QLQ Head & Neck Module. The role functioning subscale (p = 0.003), the pain subscale (p = 0.001), and the speech issues QLQ Head & Neck module subscale (p = 0.003) adversely correlated with cancer stage. Patients who received flap reconstruction significantly differed from those who did not, on the EORTC QLQ-C30 cognitive functioning (U = 139.0, p = 0.006), dyspnea (U = 391.5, p = 0.006), and diarrhea (U = 425.0, p = 0.007) subscales during the third evaluation. Differences were also found in the QLQ-H&N35 subscale of sticky saliva (U = 391.0, p = 0.006). Patients with flap reconstruction did not significantly differ from those with immediate closure after one year. Differences concerned the EORTC QLQ-C30 subscales of cognitive functioning, dyspnea, and diarrhea, and the QLQ Head & Neck Module subscale of sticky saliva on the third assessment. No statistically significant correlations were observed between tumor size and cancer stage in the fourth assessment, but the grade of cancer positively correlated with the EORTC QLQ-C30 subscale of constipation (p = 0.000). Conclusions Our study suggests that quality of life is impaired in patients with tongue cancer who have undergone surgical interventions, particularly within the first month post-operation. However, quality of life is fully restored one year after the surgical excision. Future studies should explore early interventions to help healthcare providers better treat this unique group of patients.

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“…The FACT-G also calculates a total QOL score by adding the four subscale ratings. This questionnaire was validated in the past for the Greek population [ 17 ].…”

Section: Methodsmentioning

confidence: 99%