The incidence of interstitial lung disease 1995–2005: a Danish nationwide population-based study

Abstract

BackgroundCurrent data on incidence of interstitial lung diseases (ILDs) are sparse and concerns about an increasing trend have been raised. We examined incidence rates (IRs) of ILDs and changes in IRs between 1995 and 2005.MethodsAll persons with a first-time hospital discharge or outpatient diagnosis of ILD were identified through the Danish National Registry of Patients, which covers all Danish hospitals. Crude and age-standardised IRs were computed for ILD overall, as well as stratified by ILD subcategories.ResultsA total of 21,765 patients with ILD were identified. Between 1995 and 1998 the overall standardised IR of ILD decreased from 27.14 (95% CI 25.82–28.46) per 100,000 person-years to 19.36 (95% CI 18.26–20.46) per 100,000 person-years. After 1998 the IR increased considerably, peaking at 34.34 (95% CI 32.84–35.85) per 100,000 person-years in 2002. Subsequently there was a slight decrease. The highest IR was observed in the non-specific category "Respiratory disorders in diseases classified elsewhere". By ILD subcategory, the greatest average increase during the study period was observed in "Respiratory disorders in diseases classified elsewhere".ConclusionThe incidence rate of ILD in Denmark increased during the study period, most pronounced for ILDs associated with systemic diseases.

Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review

“…Maher [22] (UK) Kornum [23] (Denmark) (n = 3720) Raghu '06 [2] (USA) (n = 120) Lai [3] (Taiwan) (n = 605)…”

“…In Europe, the highest rates were reported in the UK [1,22], with a strong increase over time. Lower rates were noted in Scandinavia [23,33] and southern Europe [36,[38][39][40], although some of these studies were likely subject to under-reporting, and a more recent study from Italy had a higher incidence [14]. In the USA, mortality statistics were lower and estimates using narrow criteria suggested an incidence of 5-8 per 100 000 [2,17,18,30].…”

Comorbidity diseases in adults with diagnosed interstitial lung diseases among inhabitants of the Silesian voivodeship, Poland

“…Dodatkowo cytowany raport wskazuje, że nie ma wyczerpują-cych danych na temat ogólnej częstości występowania chorób śródmiąższowych [18]. Współczynnik zapadalności kształtuje się na poziomie 4,1-34,3/100 000 osób w zależności od regionu [19,20]. Rosnącą liczbę zachorowań na śródmiąższowe choroby płuc odnotowano w Danii, gdzie w latach 1998-2002 wartość standaryzowanego współczynnika zapadalności wzrosła z 23,54/100 000 osób do 31,28/100 000 osób [20].…”

“…Uwidocznił się niewielki, lecz systematyczny spadek wartości standa- [20]. Z kolei badania prowadzone w Grecji wykazały niższe wartości wskaźnika (4,6/100 000 populacji) w 2004 r. [27].…”

Idiopathic pulmonary fibrosis: another step in understanding the burden of this disease

“…This may reflect missed cases elsewhere, but the fact that some studies have taken a similar approach and still yielded lower incidences [22,23] suggests there may well be true differences in IPF incidence across regions. There are several possible reasons for this: the latter of two recent studies from Italy with varying estimates speculated about environmental differences such as concentration and sources of environmental pollution [15,23], and studies from Japan have typically shown lower rates which may be due to genetic differences [24,25].…”