The Incidence of Hiatus Hernia in Pregnant Women and Its Significance

Rigler, Leo G.; Eneboe, John B.

doi:10.1016/s0096-5588(20)32385-0

Cited by 56 publications

(6 citation statements)

References 11 publications

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“… 19 However, the phrenoesophageal ligament/membrane becomes progressively lax by losing the amount of elastic tissues with aging, possibly through wear and tear due to repetitive stress of swallowing, thus predisposing to the development of hiatal hernia. 20 , 21 Loss of elasticity of the phrenoesophageal ligament/membrane may also be caused by excessive contraction of the esophageal longitudinal muscle, increased abdominal pressure as occurs in power atheletes, 22 pregnancy, 23 genetic predisposition, 24 , 25 and previous surgery. Some propose that instead of hiatal hernia being the cause of reflux esophagitis, reflux esophagitis itself is the primary culprit that initiates and sustains the esophagitis-hernia complex; a study with opossums showed that acidification of the esophageal mucosa induced longitudinal muscle contraction, resulting in shortening of the esophagus.…”

Section: Anatomy and Etiology Of Hiatal Herniamentioning

confidence: 99%

Clinical Significance of Hiatal Hernia

Hyun¹,

Bak²

2011

Gut Liver

130

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The relationship between hiatal hernias and gastroesophageal reflux disease (GERD) has been greatly debated over the past decades, with the importance of hiatal hernias first being overemphasized and then later being nearly neglected. It is now understood that both the anatomical (hiatal hernia) and the physiological (lower esophageal sphincter) features of the gastroesophageal junction play important, but independent, roles in the pathogenesis of GERD, constituting the widely accepted "two-sphincter hypothesis." The gastroesophageal junction is an anatomically complex area with an inherent antireflux barrier function. However, the gastroesophageal junction becomes incompetent and esophageal acid clearance is compromised in patients with hiatal hernia, which facilitates the development of GERD. Of the different types of hiatal hernias (types I, II, III, and IV), type I (sliding) hiatal hernias are closely associated with GERD. Because GERD may lead to reflux esophagitis, Barrett's esophagus and esophageal adenocarcinoma, a better understanding of this association is warranted. Hiatal hernias can be diagnosed radiographically, endoscopically or manometrically, with each modality having its own limitations, especially in the diagnosis of hiatal hernias less than 2 cm in length. In the future, high resolution manometry should be a promising method for accurately assessing the association between hiatal hernias and GERD. The treatment of a hiatal hernia is similar to the management of GERD and should be reserved for those with symptoms attributable to this condition. Surgery should be considered for those patients with refractory symptoms and for those who develop complications, such as recurrent bleeding, ulcerations or strictures.

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Section: Anatomy and Etiology Of Hiatal Herniamentioning

confidence: 99%

Clinical Significance of Hiatal Hernia

Hyun¹,

Bak²

2011

Gut Liver

130

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“…Some claimed that paraesophageal or HHs are up to six times more prevalent in pregnant patients[ 8 ], although pregnancy could be a risk factor for symptomatic but not overall DH. In pregnant patients with abdominal complaints, DH was demonstrated in 12.8% (multiparas 18.1%, primiparas 5.1%)[ 9 ]. Hernias disappeared in over two-thirds of reexamined patients.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Until 1935, 0.75%-1% of X-ray examinations of the stomach showed HH in the general population[ 9 , 10 ]. In that era, it was difficult to differentiate between regurgitation into the esophagus and actual herniation[ 9 ]. Currently, in the general population, sliding HH is the commonest (95%), with the prevalence of each other type of less than 1%[ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…The explanation could be higher tissue elasticity in younger patients and lower incidence of multiparas in younger ages, as observed in 1929[ 3 ]. In 1935, multiparas had a higher incidence of DH[ 9 ]. Our results show a decreasing symptomatic DH rate with increasing parity.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Maternal diaphragmatic hernia in pregnancy: A systematic review with a treatment algorithm

Augustin,

Kovač,

Karadjole

et al. 2023

World J Clin Cases

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In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.

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Symptoms and Incidence of Anemia in Hernia at the Esophageal Hiatus

Murphy¹

1943

Arch Intern Med

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The Incidence of Hiatus Hernia in Pregnant Women and Its Significance

Cited by 56 publications

References 11 publications

Clinical Significance of Hiatal Hernia

Clinical Significance of Hiatal Hernia

Maternal diaphragmatic hernia in pregnancy: A systematic review with a treatment algorithm

Symptoms and Incidence of Anemia in Hernia at the Esophageal Hiatus

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