The incidence of complications after caesarean section in 156 HIV-positive women

Semprini, A; Castagna, C.; Ravizza, Marina; Fiore, Simona; Savasi, Valeria; Muggiasca, Maria Luisa; Grossi, E.; Guerra, Brunella; Tibaldi, Cecilia; Scaravelli, Giulia; Prati, Emanuela; Pardi, Giorgio

doi:10.1097/00002030-199508000-00013

Cited by 147 publications

(80 citation statements)

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“…We did not confirm a difference neither in preterm delivery rate nor in incidence of pre-eclampsia between women using a PI-containing or a PI-free HAART regime. 6 In contrast to previous reports, 14,15 we did not see more complications after caesarean sections in our HIV-infected women than in the controls, which is similar to the findings of Avidan et al 16 This is possibly due to the normal CD4 counts in most of our HIV-infected women around labour.…”

Section: Commentsupporting

confidence: 81%

The AmRo study: pregnancy outcome in HIV‐1‐infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery

Boer¹,

Nellen

Patel

et al. 2007

BJOG

117

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Objective To explore pregnancy outcome in HIV-1-positive and HIV-negative women, and mother-to-child transmission (MTCT) according to mode of delivery under effective highly active antiretroviral therapy (HAART).Design Cohort of 143 pregnant HIV-1-infected women including a matched case-control study in a 2:1 ratio of controls to cases (n = 98).Setting Academic Medical Center in Amsterdam and Erasmus Medical Center in Rotterdam, the Netherlands.Population Consecutive referred HIV-1 infected pregnant women treated with HAART and matched control not infected pregnant women.Main outcome measures MTCT, preterm delivery, low birthweight, pre-eclampsia.Results MTCT was 0% (95% CI 0-2.1%). Seventy-eight percent of HIV-1-infected women commenced and 62% completed vaginal delivery. The calculated number of caesarean sections needed to prevent a single MTCT was 131 or more. Preterm delivery rates were 18% (95% CI 11-27) in women infected with HIV-1 and 9% (95% CI 5-13) in controls (P = 0.03). HAART used at <13 weeks of gestation was associated with a 44% preterm delivery rate compared with 21% when HAART was started at or after 13 weeks and 14% in controls. (Very) low birthweight and incidence of pre-eclampsia were not different between HIV-1 and controls.Conclusions We have not demonstrated any MTCT after vaginal delivery in women effectively treated by HAART. The HAARTassociated increase in preterm delivery rate is mainly seen after first trimester HAART use.

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Section: Commentsupporting

confidence: 81%

The AmRo study: pregnancy outcome in HIV‐1‐infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery

Boer¹,

Nellen

Patel

et al. 2007

BJOG

117

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“…This form of delivery can cause maternal complications and deals with great postoperative morbidity [25]. Prophylactic antibiotic seems to be necessary during the time of delivery.…”

Section: Introductionmentioning

confidence: 99%

HIV and Pregnancy: A Short Review

2014

J Clin Case Rep

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“…Podríamos suponer que, debido a su estado de infección, las mujeres VIH reactivas tendrían un mayor riesgo de infecciones posoperatorias. Sin embargo, los datos de estudios realizados al respecto son aún controversiales (12)(13)(14)(15) . Uno de los principales estudios que comparó las diferencias en la tasa de complicaciones entre mujeres con y sin VIH sometidas a cesárea electiva, observó un aumento en la frecuencia de complicaciones generales en el grupo de mujeres con VIH (12) .…”

Section: Introductionunclassified

“…Sin embargo, los datos de estudios realizados al respecto son aún controversiales (12)(13)(14)(15) . Uno de los principales estudios que comparó las diferencias en la tasa de complicaciones entre mujeres con y sin VIH sometidas a cesárea electiva, observó un aumento en la frecuencia de complicaciones generales en el grupo de mujeres con VIH (12) . Sin embargo, también hay estudios que han observado frecuencias similares de complicaciones en ambos grupos (16,17) .…”

Section: Introductionunclassified

“…Resultados. El 13,9% de mujeres VIH positivas presentaron CI y 9,7% del grupo control (OR: 1,5 IC95% [0,9-2,7]); las expuestas (mujeres con VIH) tuvieron mayor probabilidad de tener una infección del tracto urinario (ITU) que las no expuestas (ORa: 4,5 IC95% [1,[4][5][6][7][8][9][10][11][12][13][14]5]). Se encontró asociación entre CI y el tipo de incisión (ORa: 2,3 IC95% [1,1-4,5]) y el tiempo de hospitalización (6 frente a 3 días, p<0,001).…”

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Asociación entre el estado de infección por VIH y complicaciones infecciosas poscesárea electiva

Tejaja

Huayanay

Gutiérrez

et al. 2014

Rev Peru Med Exp Salud Publica

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Objetivos. Determinar la asociación entre VIH y complicaciones infecciosas (CI) después de una cesárea electiva. Materiales y métodos. Estudio de cohortes no concurrentes; se revisaron las historias clínicas de 237 cesáreas electivas en gestantes VIH reactivas atendidas en el Instituto Nacional Materno Perinatal de Perú, realizadas entre 2004 a 2012. Estas fueron pareadas por cirujano y fecha de cesárea con 237 gestantes VIH no reactivas. Se recogieron datos sociodemográficos, clínicos, características de la cesárea y relacionados a la infección por el VIH. Las CI se evaluaron según las recomendaciones del NHI Consensus Development Task Force. Se realizó el análisis bivariado con un nivel de significación del 5% y el cálculo del Odds Ratio (OR) con intervalo de confianza (IC) al 95%. Se construyó un modelo de regresión logística condicional. Resultados. El 13,9% de mujeres VIH positivas presentaron CI y 9,7% del grupo control (OR: 1,5 IC95% [0,9-2,7]); las expuestas (mujeres con VIH) tuvieron mayor probabilidad de tener una infección del tracto urinario (ITU) que las no expuestas (ORa: 4,5 IC95% [1,[4][5][6][7][8][9][10][11][12][13][14]5]). Se encontró asociación entre CI y el tipo de incisión (ORa: 2,3 IC95% [1,1-4,5]) y el tiempo de hospitalización (6 frente a 3 días, p<0,001). Conclusiones. Las mujeres VIH positivas sin tratamiento antirretroviral tuvieron mayor riesgo de CI; aunque no se observó mayor riesgo global de CI en expuestas después de una cesárea electiva. El principal factor de riesgo asociado a una CI poscesárea electiva en mujeres VIH positivas fue el tipo de incisión. Palabras clave: VIH; Embarazo; Cesárea; Complicaciones postoperatorias; Complicaciones infecciosas del embarazo; (fuente: DeCS BIREME). ASSOCIATION BETWEEN HIV INFECTION STATUS AND INFECTIOUS COMPLICATIONS AFTER AN ELECTIVE C-SECTION ABSTRACT Objectives:To determine the connection between HIV and infectious complications (IC) after an elective C-section. Materials and methods.A non-concurrent cohort study was conducted, in which the clinical records of 237 elective C-sections on HIV-positive pregnant women who gave birth at the Instituto Nacional Materno Perinatal (National Maternal Perinatal Institute) between 2004 and 2012 were revised. The records were matched by surgeon and C-section date, with 237 HIV-negative pregnant women. Socio-demographic and clinical data were collected, along with characteristics of the C-section and data related to the HIV infection. IC were evaluated according to the NIH Consensus Development Task Force. The descriptive analysis and the bivariate analysis were carried out with a significance level of 5% for the hypothesis tests and the calculation of the Odds Ratio (OR) with a confidence interval (CI) at 95%. A conditional logistic regression model was built. Results. IC were present in 13.9% of HIV-positive women and 9.7% of the control group (OR: 1.5 CI95% [0.9-2.7]); those who were exposed (women with HIV) were more likely to have a urinary tract infection (UTI) than those who were not exposed (OR...

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The incidence of complications after caesarean section in 156 HIV-positive women

Cited by 147 publications

References 0 publications

The AmRo study: pregnancy outcome in HIV‐1‐infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery

The AmRo study: pregnancy outcome in HIV‐1‐infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery

HIV and Pregnancy: A Short Review

Asociación entre el estado de infección por VIH y complicaciones infecciosas poscesárea electiva

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