The Incidence of Cleft Lip and Palate in Northern Ireland from 1980–1990

Gregg, T A; Boyd, Dorothy; Richardson, Andrew

doi:10.1179/bjo.21.4.387

Cited by 70 publications

(47 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In studies conducted on a Caucasian population, the incidence of clefts in Northern Ireland was found to be 1.28 for every 1000 live births [18]. The incidence of cleft defects in the Stockholm County in Sweden was found to be 2.0 : 1000 live births [19].…”

Section: Discussionmentioning

confidence: 99%

Incidence of Orofacial Clefts in Kumasi, Ghana

Agbenorku

Yore

Danso

et al. 2013

ISRN Plastic Surgery

View full text Add to dashboard Cite

Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29.85 years (range 18–40 years). The male : female ratio for the orofacial anomalies babies was 1.3 : 1; the male : female ratio was 0.5 : 1 in the cleft lip group, 1.3 : 1 in the cleft lip and palate group, and 4 : 1 in the cleft palate group. The majority of clefts were unilateral (69.4%, n=25), with females (n=14) outnumbering males (n=11). A family history of cleft was recorded with five babies (13.9%). Associated congenital anomalies were recorded in seven (19.4%) cleft lips and/or palates. Conclusion. The incidence of 1 in 763 live births found in this study indicates that cleft lip/palate is a common congenital anomaly in Kumasi.

show abstract

Section: Discussionmentioning

confidence: 99%

Incidence of Orofacial Clefts in Kumasi, Ghana

Agbenorku

Yore

Danso

et al. 2013

ISRN Plastic Surgery

View full text Add to dashboard Cite

show abstract

“…More males than females were affected, and more males had complete clefts. Unilateral clefts were most common on the left hand side 6 . Few prevalence studies discriminate between unilateral CLP and bilateral CLP, although a prevalence ratio of 4:1 has been reported.…”

Section: Prevalencementioning

confidence: 99%

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Hodgkinson

Brown

Duncan

et al. 2005

Fet. Matern. Med. Rev.

View full text Add to dashboard Cite

show abstract

“…Generally, boys are affected more than girls with a ratio of about 3 : 2 [5]. Males are more likely than females to have a cleft lip with or without cleft palate, while females are at a slightly greater risk for cleft palate alone [6,7]. Since facial mesenchyme is derived from neural crest, it is postulated that periconceptional folic acid supplementation may reduce the occurrence of offspring with orofacial clefts [8].…”

Section: Introductionmentioning

confidence: 99%

Orofacial Clefts: A Worldwide Review of the Problem

Agbenorku

2013

ISRN Plastic Surgery

View full text Add to dashboard Cite

Orofacial cleft is one of the commonest congenital abnormalities which impacts negatively on the life of the individual and to a large extent affects the family. Caused by the interaction of environmental and genetic factors, this abnormality brings about decreased quality of life. Management of this abnormality entails a team involving a cleft surgeon, speech therapist, dentist, orthodontists, and so forth. This study involves the review of the various literatures on orofacial clefts, discussing the problems on the genetic basis, associated syndromes, and their management. Counseling of prospective mothers should be promoted to ensure that the abnormality is prevented at the early stages. Education on orofacial clefts should be promoted to create awareness on its preventive measures. Much attention must be geared towards cleft genetics studies to identify potential risk factors which might be predisposing individuals to the anomaly.

show abstract

The Incidence of Cleft Lip and Palate in Northern Ireland from 1980–1990

Cited by 70 publications

References 6 publications

Incidence of Orofacial Clefts in Kumasi, Ghana

Incidence of Orofacial Clefts in Kumasi, Ghana

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Orofacial Clefts: A Worldwide Review of the Problem

Contact Info

Product

Resources

About