The Incidence of Allergic Disorders in First Degree Relatives of Neonates with Transient Tachypnea of Neonate

Safari, Mojgan

doi:10.7860/jcdr/2015/12126.6309

Cited by 1 publication

(2 citation statements)

References 19 publications

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“…In an earlier study, Safari et al had reported a weak association between asthma in older children and TTN in later born younger siblings. 18 In the 35 infants in their study, bronchial asthma was present in 2.9% (n = 1) and atopic dermatitis was present in 5.7% (n = 2) with allergic rhinitis being absent. These authors also reported a similar incidence of allergic disorders, including asthma, in first-degree relatives of babies with and without TTN, despite there being no cases of asthma in the siblings of the 35 healthy controls.…”

Section: Discussionmentioning

confidence: 79%

“…17 There is no clear evidence in the literature concerning the presence of asthma in the siblings of neonates and the likelihood of that neonate developing TTN. One of the few studies on the role of allergic disorders of older siblings of the neonates developing TTN was reported by Safari et al 18 However, the study of Safari et al included only 35 infants diagnosed with TTN, and then, compared them with a matched group of 35 healthy neonates. This small group size was a limitation of the study.…”

Section: Gundogdumentioning

confidence: 99%

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Effect of sibship asthma on newborns with transient tachypnea of the newborn (TTN)

Gündoğdu

2020

Clinical Respiratory J

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Background: A number of studies have demonstrated that transient tachypnea of the newborn (TTN) is a risk factor for later asthma. The present study attempts to determine whether older sibling asthma is a risk factor for TTN. Methods: Medical records of 1318 newborns from neonatal intensive care and delivery units were studied. None of the subjects were first-born, and thus, all had older siblings. Clinical data of mothers and their children were obtained from medical records. Data items included date of birth, gestational age (GA) at birth, birth weight, gender, mode of delivery including Normal Spontaneous Delivery or caesarean section (CS) and whether pre-labour CS or not, reasons for CS, number of pregnancies, number of children, asthma of mothers and siblings, whether the newborn had TTN or not. Logistic regression analysis was used to assess the association between siblings' asthma and TTN. Results: Pre-labour CS, maternal asthma, GA, babies with large and small birth weight for GA, number of pregnancies and children (three and more) were found to be significantly associated with TTN. Siblings' asthma was found to be independently associated with a diagnosis of TTN. Conclusions: Both pre-labour CS and mothers with asthma were common risk factors for the development of TTN. An association was present between TTN and siblings' asthma even in infants whose mothers did not have asthma. K E Y W O R D S risk factors, siblings' asthma, transient tachypnea of newborn How to cite this article: Gundogdu Z. Effect of sibship asthma on newborns with transient tachypnea of the newborn.

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Section: Discussionmentioning

confidence: 79%

Section: Gundogdumentioning

confidence: 99%