The Incidence of Acute Peritonitis Secondary to Different Sites of Viscus Perforation

Abstract

The incidence of peritonitis secondary to viscus perforation will be examined to determine the most common sites of perforation and associated comorbidities. MethodsThis is a retrospective observational study based on data collected from the King Fahad Hospital of the University (KFUH). This research targeted patients who had viscus organ perforation and the relation of peritonitis secondary to it. The sample was taken from patients under the care of the General Surgery Department from the first of Feb 2016 to the 12th of Sep 2022. The final sample consisted of 450 patients. The method of diagnosis of peritonitis was mainly clinical, and the surgical approach was either through an exploratory laparotomy or a diagnostic laparoscopy. Incidental findings of viscus organ perforation were noted in addition to certain postoperative complications (e.g., adhesions) and hospital stay. ResultsAnalysis of the results showed a significant relation (p<0.001) between viscus organ perforation and peritonitis. The most common comorbidities associated with secondary peritonitis were hypertension (12, 24.5%), diabetes mellitus (10, 20.4%), any abdominal mass (3, 6.1%), and inflammatory bowel disease (1, 2%). However, a chi-square analysis has shown no significant association between peritonitis and the targeted associated comorbidities. ConclusionPerforation of the small intestine carries the biggest association with peritonitis incidence, in addition to comorbidities such as hypertension and diabetes mellitus. Further study to establish the value of these factors might contribute to decreasing the morbidity and mortality of secondary peritonitis.

Differentiated Approach to Antihypoxic, Endoportal and Phage Therapy for Advanced Purulent Peritonitis

“…Secondary peritonitis and intra-abdominal sepsis are a global issue in public healthcare. The life-threatening systemic damage resulting from intra-abdominal sepsis has long been known, but remains insufficiently studied [1][2][3][4][5]. Direct surgical treatment for diffuse peritonitis is well developed and understood, however, there are not enough systemic treatment methods to control the subsequent systemic inflammatory reaction [6][7][8].…”