The informal payments in the Romanian medical system have generated several ethical dilemmas, as they are regarded either negatively, as an act of corruption, either positively, as gratifications or "small attentions" from the part of the patient. According to a study of 2013 of the European Commission, the percentage of the Romanian patients claiming that they offered attentions to the physicians is of 28%, whereas the European average is of 5%. Our study starts from the assumption that the practice of informal payments in the Romanian medical system is not based only on the low remuneration level, but mostly on deep "socio-cultural roots". A first aspect approached referred to values specific to the Romanian people, based on the survey of several works and research whose results are thoroughly presented in the specialty literature, but also the analysis of statistics or debates in the media. The gift practice in Romanians is a national-cultural feature intensely debated by several authors. Our assumption is that this cultural specificity in conjunction with other factors (for instance, specific values, such as safety, sacrifice, hospitality, kindness, tolerance, but also the hierarchical submission or the importance of the group opinion, the attitude towards the risk) can be factors which explain the practice and the magnitude of the informal payments phenomenon in the autochthonous medical system. The results of our study can be useful in adopting certain substantiated political and managerial strategies and adapted to the socio-cultural context, which take into account the deep cause of the situation.