The in vitro assessment of anti proliferation activity of crude diethyl ether extract of Dendrophthoe species against to myeloma culture cell

Lazuardi, Mochamad

doi:10.20473/j.djmkg.v41.i1.p5-9

Cited by 2 publications

(2 citation statements)

References 3 publications

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“…The n -hexane fraction of DP leaves was unveiled to have suppressive effects on K562 cells with an IC 50 value of 38.69% ( Elsyana et al, 2016 ). Using methylene blue solution, a diethyl ether extract of DP stem barks was tested on myeloma culture cells, resulting in antiproliferation activity at doses ranging from 11.0 g/mL to 44 g/mL ( Lazuardi, 2008 ).…”

Section: Pharmacologymentioning

confidence: 99%

Dendrophthoe falcata (L.f.) Ettingsh. and Dendrophthoe pentandra (L.) Miq.: A review of traditional medical uses, phytochemistry, pharmacology, toxicity, and applications

et al. 2023

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Dendrophthoe falcata (L.f.) Ettingsh. (DF) and Dendrophthoe pentandra (L.) Miq. (DP) have been traditionally used for the treatment of various ailments, such as cancer, ulcers, asthma, paralysis, skin diseases, tuberculosis, and menstrual troubles, in the ethnomedicinal systems of India and Indonesia. Currently, the chemical structures of 46 compounds have been elucidated from DF and DP, including flavonoids, triterpenes, tannins, steroids, open-chain aliphatics, benzyl derivates, and cyclic chain derivatives. In vitro assays have revealed their anti-tumor and anti-microbial activities. In vivo studies have unraveled their pharmacological properties against tumors, depression, fertility disorders, inflammatory responses, and so on. Additionally, their weak toxicity to rats and brine shrimp, as well as their promising applications for pharmaceutical preparations and combined medication, were also revealed. Herein, we not only recapitulated traditional medical uses, phytochemistry, pharmacology, toxicity, and applications of DF and DP but also discussed current research limitations and future perspectives, which are instructive for those interested in them and are committed to advancing parasitic plants to the Frontier of phytomedicine. We highlighted that DF and DP will become promising medical plants rather than being discarded as notorious pests, provided that more and deeper research is undertaken.

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Section: Pharmacologymentioning

confidence: 99%

Dendrophthoe falcata (L.f.) Ettingsh. and Dendrophthoe pentandra (L.) Miq.: A review of traditional medical uses, phytochemistry, pharmacology, toxicity, and applications

et al. 2023

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“…Nowadays, people consume lots of water infusion of the duku's mistletoe leaf as anti-cancer compounds, especially anti-breast cancer. Methanol extract of duku's mistletoe leaf (Loranthaceae Dendrophthoe spec.,) content 20 μg.ml-1 , has the potential inhibition of myeloma cell growth in vitro (Lazuardi, 2011). Therefore, it is necessary to do a preliminary test to determine the activity of flavonoids that contained in duku's mistletoe leaf as anticancer by testing the toxicity and antioxidant activity.…”

Section: Introductionmentioning

confidence: 99%

Proceeding ICEST Labuan Bajo 2018

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2023

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The in vitro assessment of anti proliferation activity of crude diethyl ether extract of Dendrophthoe species against to myeloma culture cell

Cited by 2 publications

References 3 publications

Dendrophthoe falcata (L.f.) Ettingsh. and Dendrophthoe pentandra (L.) Miq.: A review of traditional medical uses, phytochemistry, pharmacology, toxicity, and applications

Dendrophthoe falcata (L.f.) Ettingsh. and Dendrophthoe pentandra (L.) Miq.: A review of traditional medical uses, phytochemistry, pharmacology, toxicity, and applications

Proceeding ICEST Labuan Bajo 2018

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