Abstract:Ibuprofen is classified as a BCS class II because of its low solubility and high permeability. Inclusion complex formation using β-cyclodextrin is one method to increase a drug’s solubility. In addition to the method of increasing the solubility, the choice of dosage form and route of administration has a big role in the success of therapy because it can increase the onset of action of drugs while avoiding side effects. Rectal suppositories can provide a faster antipyretic effect than oral preparations. The pu… Show more
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