The Importance of Tumor Attachment to the Carotid Artery

Kennedy, John; Krause, Charles J.; Loevy, Sara S.

doi:10.1001/archotol.1977.00780190050002

Cited by 114 publications

(50 citation statements)

References 14 publications

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“…However, local control rates of up to 50% and a 5 y survival rate of 20% have been reported with re-EBRT. [19][20][21] Currently, there is no effective systemic therapy for recurrent head and neck carcinomas. The combination of concomitant chemotherapy with re-irradiation of recurrent head and neck carcinomas after previous full-dose radiotherapy yielded encouraging median survivals and long-term diseasefree survival rate of up to 24%.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck

Jiang

Meng²,

Wang³

et al. 2010

Cancer Biology & Therapy

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Section: Discussionmentioning

confidence: 99%

Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck

Jiang

Meng²,

Wang³

et al. 2010

Cancer Biology & Therapy

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“…Regarding retroperitoneal sarcomas. 24 which characteristically do not respond to radiotherapy and/or chemotherapy, the treatment result fundamentally depends on the possibility for complete resection of, and on the degree of the tumor malignancy.…”

Section: Discussionmentioning

confidence: 99%

Arterial Reconstructions Associated With the Resection of Malignant Tumors.

Nishinari¹,

Wolosker²,

Yazbek³

et al. 2006

Clinics

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“…In these cases, when performing the resection of the tumor, the carotid artery can be approached in three ways: sub-adventitial dissection, 12,13 carotid resection with ligature of the stumps 4,5,6 or carotid resection with reconstruction of the flow. 7,11,14 Resection of the tumor with sub-adventitial dissection is possible in some cases, when there is no firm adherence of the tumor to the carotid.…”

Section: Discussionmentioning

confidence: 99%

“…With this technique, the cerebral blood flow is not interrupted, although the presence of microscopic tumor invasion of the vessel wall causes a high local recurrence rate for the disease. 13,15 In addition there is a risk of arterial rupture because of erosion of the wall after a proliferation of tumor cells, which may be increased after adjuvant radiotherapy. 16 In cases of superficial invasion with the possibility of shaving the tumor from the artery, the rotation of a thin muscle flap (scapula elevator) for vessel protection and implantation of catheters for brachytherapy is a viable alternative.…”

Section: Discussionmentioning

confidence: 99%

Carotid reconstruction in patients operated for malignant head and neck neoplasia

et al. 2002

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CONTEXT: Patients with malignant head and neck neoplasia may present simultaneous involvement of large vessels due to the growth of the tumoral mass. The therapeutic options are chemotherapy, radiotherapy, surgery or combined treatments. OBJECTIVE: To analyze the result of surgical treatment with carotid reconstruction in patients with advanced malignant head and neck neoplasia. DESIGN: Prospective. SETTING: Hospital do Câncer A.C. Camargo, São Paulo, Brazil. PARTICIPANTS: Eleven patients operated because of advanced malignant head and neck neoplasia that was involving the internal and/or common carotid artery. MAIN MEASUREMENTS: By means of clinical examination, outpatient follow-up and duplex scanning, we analyzed the patency of the carotid grafts, vascular and non-vascular complications, disease recurrence and survival of the patients. RESULTS: Six patients (54.5%) did not present any type of complication. There was one vascular complication represented by an occlusion of the carotid graft with a cerebrovascular stroke in one hemisphere. Non-vascular complications occurred in five patients (45.5%). During the follow-up, eight patients died (72.7%), of whom seven had loco-regional tumor recurrence and one had pulmonary and hepatic metastases (at an average of 9 months after the operation). Seven of these patients presented functioning grafts. The three patients still alive have no tumor recurrence and their grafts are functioning (an average of 9 months has passed since the operation). CONCLUSIONS: Patients with advanced malignant head and neck neoplasia involving the carotid artery that are treated surgically present a prognosis with reservations. When the internal and/or common carotid artery is resected en-bloc with the tumor, arterial reconstruction must be performed. The long saphenous vein is a suitable vascular substitute.

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The Importance of Tumor Attachment to the Carotid Artery

Cited by 114 publications

References 14 publications

Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck

Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck

Arterial Reconstructions Associated With the Resection of Malignant Tumors.

Carotid reconstruction in patients operated for malignant head and neck neoplasia

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