The Importance of Population-Wide Sodium Reduction as a Means to Prevent Cardiovascular Disease and Stroke

Prevención secundaria post infarto agudo de miocardio en hospitales públicos: implementación y resultados de las garantías GES

“…Pese a esto, el control de la presión arterial fue sub óptimo, lo que en otros estudios se ha relacionado con estilos de vida poco saludables [43][44][45] ; en nuestro estudio estos pacientes presentaron un IMC mayor. La presión arterial elevada en pacientes post-infarto se asocia con mayor riesgo de muerte y nuevos eventos coronarios 46 .…”

Dietary salt intake and stroke

“…The risk factors for stroke include hypertension, coronary heart diseases, diabetes and obesity [1] , in which hypertension is the top risk factor. Worldwide, hypertension is the leading preventable risk factor for death; and causes 54% of strokes [2] . While stroke is one of the leading causes of mortality in the industrialized countries, the effects of elevated blood pressure on the Asian population also raise a concern.…”

“…A diverse body of evidence, including animal, clinical and epidemiological studies, has implicated excess dietary sodium intake as one of the major factors associated with the development of hypertension and subsequent increase in stroke risk [2] . Canadian Stroke Network estimated that bringing consumption of sodium to healthy levels (less than 1500 mg/d) would reduce the incidence of hypertension by 30%, which amounts to over a million Canadians [4] .…”

“…Some of the most convincing clinical evidence on the effects of sodium on blood pressure comes from rigorously controlled, dose-response trials [2] . The DASH (Dietary Approaches to Stop Hypertension)-Sodium trial is the largest of three major dose-response trials.…”

“…In addition, increased dietary intake of sodium has numerous adverse effects that are independent of blood pressure. These include ventricular fibrosis, kidney damage, gastric cancer, disordered mineral metabolism, oxidative stress and endothelial dysfunction [2] .…”