“…One study, reporting the use of FA in planning laser treatment for DME, found that FA only improved treatment accuracy by 49% to 55% 460 , by significantly improving the treatment accuracy of only one of the four retinal specialists studied 460 . The authors suggest that FA may improve treatment-planning accuracy by reducing either over-treatment or under-treatment, and may help clinicians identify ischaemic areas, for which ETDRS guidelines mandate treatment 461 .…”
Section: Recommendations For Routine Fa In Managing Drmentioning
“…One study, reporting the use of FA in planning laser treatment for DME, found that FA only improved treatment accuracy by 49% to 55% 460 , by significantly improving the treatment accuracy of only one of the four retinal specialists studied 460 . The authors suggest that FA may improve treatment-planning accuracy by reducing either over-treatment or under-treatment, and may help clinicians identify ischaemic areas, for which ETDRS guidelines mandate treatment 461 .…”
Section: Recommendations For Routine Fa In Managing Drmentioning
“…Intravenous (IV) fluorescein angiography (FA) is the clinical gold standard for assessing retinal vasculature, revealing the extent of disease and response to treatment [1]. Despite its utility, the IV injection of fluorescein dye is considered invasive, and has been reported to cause rare but potentially severe systemic adverse reactions [2][3][4][5][6].…”
Recent advances to the adaptive optics scanning light ophthalmoscope (AOSLO) have enabled finer in vivo assessment of the human retinal microvasculature. AOSLO confocal reflectance imaging has been coupled with oral fluorescein angiography (FA), enabling simultaneous acquisition of structural and perfusion images. AOSLO offset pinhole (OP) imaging combined with motion contrast post-processing techniques, are able to create a similar set of structural and perfusion images without the use of exogenous contrast agent. In this study, we evaluate the similarities and differences of the structural and perfusion images obtained by either method, in healthy control subjects and in patients with retinal vasculopathy including hypertensive retinopathy, diabetic retinopathy, and retinal vein occlusion. Our results show that AOSLO OP motion contrast provides perfusion maps comparable to those obtained with AOSLO FA, while AOSLO OP reflectance images provide additional information such as vessel wall fine structure not as readily visible in AOSLO confocal reflectance images. AOSLO OP offers a noninvasive alternative to AOSLO FA without the need for any exogenous contrast agent. 458-461 (1990). 21. T. Hara, M. Inami, and T. Hara, "Efficacy and safety of fluorescein angiography with orally administered sodium fluorescein," Am.
“…A randomized controlled trial to conclusively demonstrate visual benefit would be prohibitively expensive. 6 Could other noninvasive methods of assessing macular morphology such as optical coherence tomography be used to target laser treatments in the early stages of the disease? At present, UK audit standards for diabetic maculopathy treatment require assessment of waiting times and access to treatment but not of the visual outcome.…”
The iris root was displaced into the bleb through the break and incarcerated, thus blocking the aqueous humor outflow and causing the IOP to rise rapidly, which is one of the complications of NPTS. 1 UBM can clearly image the anterior segment of the eye, so it is widely used to evaluate the bleb and to explore the potential reasons for failure of the bleb after NPTS. 2,3 However, in this case, from the UBM picture, we could not identify the iris root location and its relationship with ciliary. In addition, there was a strong reflective cycle in the bleb, which could easily be misinterpreted as a bleb encapsulation. However, an encapsulated bleb would not be associated with an acute increase in IOP, as encapsulation is a slow process. In combination with the supplementary clinical examination results, we concluded that the strong reflective cycle was actually the incarcerated iris. To the best of our knowledge, this exceptional phenomena has not been reported before.NPTS, which does not enter the anterior chamber during the operation, and in the absence of an iridectomy, would ensure little postoperation inflammation. However, a small percentage of patients were observed with an increasing IOP at prolonged periods after NPTS, which may be due to rupture of the trabeculo-decemet's membrane or adherence of iris root to the membrane. 1 These complications, followed up with NPTS, were induced by a consistent existing pressure difference between the upper and lower iris surface after the surgery. Therefore, it is worth considering to perform a laser iridectomy at the surgical area, before the NPTS, as a means of preventing these surgical complications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.