The importance of fatigue cognitions in chronic hepatitis C infection

Zalai, Dóra; Sherman, Morris; McShane, Kelly; Shapiro, Colin M.; Carney, Colleen E.

doi:10.1016/j.jpsychores.2014.11.011

Cited by 22 publications

(25 citation statements)

References 55 publications

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“…According to this model, primary disease factors, such as anaemia, inflammation, and dialysis may trigger fatigue, yet, how patients react cognitively, emotionally, and behaviourally to the initial symptom of fatigue may worsen, maintain and perpetuate fatigue over time (Figure 1; Donovan et al, 2007;van Kessel & Moss-Morris, 2006). The importance of these factors in maintaining and perpetuating fatigue has been extensively documented in other conditions, including multiple sclerosis (MS), rheumatoid arthritis (RA), and cancer (Ali et al, 2017;Als en et al, 2010;Grayson et al, 2013;Jopson & Moss-Morris, 2003;van Kessel & Moss-Morris, 2006;Zalai et al, 2015). Excessive rest may in turn lead to deconditioning, poor sleep and physiological arousal related to anxious mood, and lead to the perpetuation of fatigue (van Kessel & Moss-Morris, 2006; Van der Werf et al, 2003;Vercoulen et al, 1998;Wessely et al, 1998).…”

Section: Statement Of Contributionmentioning

confidence: 99%

A prospective study of fatigue trajectories among in‐centre haemodialysis patients

Picariello

Norton

Moss‐Morris

et al. 2019

British J Health Psychol

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Objectives. Fatigue is common and debilitating among dialysis patients. The aim of this study was to understand the longitudinal trajectory of fatigue and consider sociodemographic, clinical, and psychological factors that are related to variation in fatigue levels over time.Design. A prospective study of fatigue with yearly assessments over 3 years among prevalent in-centre haemodialysis (HD) patients.Methods. Fatigue severity was measured using the Chalder Fatigue Questionnaire and fatigue-related functional impairment using the Work and Social Adjustment Scale. The trajectories of fatigue outcomes were examined using piecewise growth models, using length of time on dialysis as time. Sociodemographic, clinical, and psychological predictors of fatigue were assessed using linear growth models, using follow-up time.Results. One hundred and seventy-four prevalent HD patients completed baseline measures, 118 at 12 months, 84 at 24 months, and 66 at 36 months. Fatigue severity scores decreased by 0.15 each year. Fatigue-related functional impairment increased by 1.17 each year. In adjusted linear growth models, non-white ethnicity was a significant predictor of lower initial fatigue severity (B = À2.95, 95% CI À5.51 to À0.40) and a greater reduction in fatigue severity of 1.60 each year (95% CI 0.35-2.36). A one-point increase in damage beliefs was associated with a 0.36 increase in fatigue-related functional impairment each year (95% CI À0.61 to À0.01).Conclusion. Damage beliefs predicted an increase in fatigue-related functional impairment over time. However, the data strongly suggested that fatigue outcomes vary by length of time on dialysis.

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Section: Statement Of Contributionmentioning

confidence: 99%

A prospective study of fatigue trajectories among in‐centre haemodialysis patients

Picariello

Norton

Moss‐Morris

et al. 2019

British J Health Psychol

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“…However, most studies to date have been cross‐sectional and very few interventional . Furthermore, unlike other long‐term conditions, the ways in which patients perceive, interpret and react to fatigue symptoms in IBD remain largely unexplored …”

Section: Introductionmentioning

confidence: 99%

The contribution of clinical and psychosocial factors to fatigue in 182 patients with inflammatory bowel disease: a cross‐sectional study

Artom

Czuber‐Dochan

Sturt

et al. 2016

Aliment Pharmacol Ther

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“…Therefore, through the use of PRO instruments, clinical investigators have been able to establish that patients with HCV infection experience tremendous impairment in their health related quality of life (HRQOL) and well-being, especially in the domains of physical functioning, mental health, and work productivity as a result of the virus itself [64][65][66][67][68][69][70][71][72][73][75][76][77][78][79][80]. Additionally, multivariate analyses have determined that disease severity (presence of advanced liver disease), and psychiatric co-morbidities, especially depression, are important drivers of PRO impairment [67,75,76,78].…”

Section: Patient Reported Outcomes Related To Hcv Infectionmentioning

confidence: 99%

Hepatitis C infection: A multi-faceted systemic disease with clinical, patient reported and economic consequences

Younossi

Birerdinc

Henry

2016

Journal of Hepatology

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Hepatitis C virus infection (HCV) affects approximately 170-200 million individuals globally. HCV is one of the primary causes of hepatocellular carcinoma (HCC) and cirrhosis and has been identified as the leading indication for liver transplantation in most Western countries. Because HCV is a systemic disease with hepatic, extrahepatic, economic and patient reported consequences, it is important for healthcare practitioners to understand the comprehensive and multi-faceted picture of this disease. In this context, it is important to fully appreciate the impact of HCV on the individual patient and the society. With the recent advent of the new generation of direct antiviral agents, the long standing goal of eradicating HCV in most infected patients has been accomplished. Therefore, now more than ever, it is critical to assess the total benefits of sustained virological response in a comprehensive manner. This should not be limited to the clinical benefits of HCV cure, but also to account for the improvement of patient reported health and economic outcomes of HCV cure. It is only through this comprehensive approach to HCV and its treatment that we will understand the full impact of this disease and the tremendous gains that have been achieved with the new antiviral regimens.

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The importance of fatigue cognitions in chronic hepatitis C infection

Cited by 22 publications

References 55 publications

A prospective study of fatigue trajectories among in‐centre haemodialysis patients

A prospective study of fatigue trajectories among in‐centre haemodialysis patients

The contribution of clinical and psychosocial factors to fatigue in 182 patients with inflammatory bowel disease: a cross‐sectional study

Hepatitis C infection: A multi-faceted systemic disease with clinical, patient reported and economic consequences

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