The Importance of Endophytic Fungi from the Medicinal Plant: Diversity, Natural Bioactive Compounds, and Control of Plant Pathogens

Al-Ani, Laith Khalil Tawfeeq

doi:10.1007/978-981-13-9566-6_9

Cited by 9 publications

(5 citation statements)

References 142 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, numerous studies had demonstrated that endophytic fungi bioactive substances have therapeutic effects against several plants and animal pathogens [19]. Therefore, it is necessary to isolate and identify endophytic microorganisms due to their medicinal properties [25]. In the present study, endophytes were isolated and identified from the medicinal plant C. annuum L. seeds, and their antimicrobial activity was assessed.…”

Section: Discussionmentioning

confidence: 93%

Isolation of yeast endophytes from healthy seeds of Capsicum annuum L. and assessment of their antimicrobial activity

Bhuyan,

Hansepi,

Akhtar

et al. 2023

J App Biol Biotech

View full text Add to dashboard Cite

Endophytic fungi have been frequently detected in various plant species, but an understanding of the characteristics and biological properties of endophytic fungi of Capsicum annuum L. seeds has not yet been carried out. The present work was designed to isolate the endophytic fungi associated with the seeds of C. annuum L. and a preliminary assessment of the antimicrobial activity of the crude metabolites produced by the isolated endophytes against some human test pathogens. The healthy seeds, after surface sterilization, were inoculated on different growth mediums, namely Potato Dextrose Agar (PDA), Host Extract + Agar (HEA), and Water Agar (WA) under aseptic conditions and incubated at 24±1°C for several days. The result indicated that the seeds were colonized by several yeast endophytes. The maximum number of yeast endophytes was isolated from the PDA medium (32), followed by HEA (8) and WA medium (0), and the endophytes formed six distinct colonies (CA1-CA6). Antimicrobial activity assay of the crude metabolites of the yeast isolates cultured on Potato Dextrose Broth (PDB) revealed that yeast isolates CA5 had higher antimicrobial activity than isolate CA1 against all human pathogens. In addition, crude metabolites of a yeast isolate CA1 showed antimicrobial activity against MTCC 736 (Bacillus subtilis) (when cultured on 50% PDB) and MTCC 737 (Staphylococcus aureus) (when cultured on 12.5% and 25% PDB). Furthermore, antimicrobial activity of the crude metabolites of yeast isolates CA5 was observed against MTCC 736 (B. subtilis) (highest when cultured on 25% PDB) and MTCC 424 (Pseudomonas aeruginosa) (highest when cultured on 12.5% and 25% PDB). In comparison, isolate CA5 showed the highest antimicrobial activity against all the tested human pathogens than isolate CA1.

show abstract

Section: Discussionmentioning

confidence: 93%

Isolation of yeast endophytes from healthy seeds of Capsicum annuum L. and assessment of their antimicrobial activity

Bhuyan,

Hansepi,

Akhtar

et al. 2023

J App Biol Biotech

View full text Add to dashboard Cite

show abstract

“…Interestingly, the discovery of endophytes was welcomed by the scientific community, as an additional arsenal for the fight against pathogenic organisms. This has made the past few decades witness an increased reports on endophytes in the mycological literature [40]. Being presented as microorganisms present in the plant that are of great biodiversity that generate promising molecules of drug candidates with versatile pharmacological activities [40,41].…”

Section: Endophytes As Sources Of Anti-bacterial Agentsmentioning

confidence: 99%

“…This has made the past few decades witness an increased reports on endophytes in the mycological literature [40]. Being presented as microorganisms present in the plant that are of great biodiversity that generate promising molecules of drug candidates with versatile pharmacological activities [40,41]. These promising outcomes have raised the interest of more scientists to delve into the study of endophyte [42,43].…”

Section: Endophytes As Sources Of Anti-bacterial Agentsmentioning

confidence: 99%

New options in drug discovery: Endophyte technology

Ifeoma Sandra Asogwa,

Christopher Osita Eze,

Anthony Ikechukwu Onah

et al. 2024

Int. J. Sci. Res. Arch.

View full text Add to dashboard Cite

Antimicrobial discovery has traditionally focused on sources from plants, animals and microorganisms. However, with the reoccurring incidences of multidrug-resistant organisms (MDROs) towards the in-use antibiotics and the problem of over- exploration of plants that is heavily altering the ecosystem, the need for other sustainable means of acquiring novel drugs becomes imperative. In a bid to ameliorate these issues, researchegrs have resorted to the use of some endosymbiotic microorganisms, known as endophytes. These are microorganisms inhabiting the internal part of plants, which have been verified to possess great potentials to bioengineer novel products, for therapeutic purposes. The discovery of endophytic microorganisms has come with so many promises of alleviating the challenges of an increasingly daunting multidrug- resistant strain of pathogenic microbes, which have become a global issue in health care delivery. They can be harnessed and utilized in the generation of active ingredients for drug production, instead of the incessant cutting down or harvesting of plants or plant parts, which destroys nature, resulting in global warming and world climate problems. This systematic review is on endophytic technology as a new alternative in drug discovery.

show abstract

“…Plant growth promoting rhizobacteria (PGPR) biocontrol agents showed the ability to control several plant pathogens (Al-Ani, 2006 , 2017a , 2018a , b ; Al-Ani and Al-Ani, 2011 ; Mohammed et al, 2011 , 2014 ; Al-Ani et al, 2020b ; Soumare et al, 2021 ). Trichoderma is a more interesting genus used in biological control that has shown efficacy in the management of several plant diseases (Al-Ani et al, 2013a , 2018 ; Al-Ani and Albaayit, 2018a , b ; Al-Ani, 2019a , b ; Al-Ani and Mohammed, 2020 ) and has been detected as act endophyte in plants (Al-Ani, 2019c , d , e ).…”

Section: Introductionmentioning

confidence: 99%

“…Non-pathogenic fungi and entomopathogenic fungi controlling plant disease and pests (Al-Ani et al, 2018 ; Al-Ani, 2019c , f ; Gupta et al, 2022 ), have the ability to manage some plant diseases and play a role in sustainable agriculture by enhancing plant vigor (Al-Ani and Salleh, 2010 ; Al-Ani et al, 2013b ; Al-Ani, 2017b , 2019d , e ; Al-Ani and Furtado, 2020 ; Kisaakye et al, 2022 ). In addition, many natural compounds and plant extracts are helpful in controlling plant diseases and pests (Al-Ani et al, 2012 ; Mohammed et al, 2012 , 2013 ; Adetunji et al, 2019 ; Garganese et al, 2019 ; Jatoi et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Strategy of Nematophagous Fungi in Determining the Activity of Plant Parasitic Nematodes and Their Prospective Role in Sustainable Agriculture

Al-Ani

Soares

Sharma

et al. 2022

Front. Fungal Biol.

Self Cite

View full text Add to dashboard Cite

In this review, we supply a framework for the importance of nematophagous fungi (nematophagous fungi [NF]) and their role in agricultural ecosystems. We characterize the taxonomy, diversity, ecology, and type of NF, depending on their interaction with plant-parasitic nematodes (PPNs). We described potential mechanisms of NF in the control of PPNs, the efficiency and methods of utilization, and the use of nematicides in sustainable agriculture. We explain the utilization of NF in nanotechnology as a new approach. NF are significant in the soil for having the effective potential for use in sustainable agriculture. These types of fungi belong to wide taxa groups, such as Ascomycota, Basidiomycota, and other groups. Diverse NF are available in different kinds of soil, especially in soils that contain high densities of nematodes. There is a relationship between the environment of nematodes and NF. NF can be divided into two types according to the mechanisms that affect nematodes. These types are divided into direct or indirect effects. The direct effects include the following: ectoparasites, endoparasites, cyst, or egg parasites producing toxins, and attack tools as special devices. However, the indirect effect comprises two groups: paralyzing toxins and the effect on the life cycle of nematodes. We explained the molecular mechanisms for determining the suitable conditions in brief and clarified the potential for increasing the efficacy of NF to highly impact sustainable agriculture in two ways: directly and indirectly.

show abstract

The Importance of Endophytic Fungi from the Medicinal Plant: Diversity, Natural Bioactive Compounds, and Control of Plant Pathogens

Cited by 9 publications

References 142 publications

Isolation of yeast endophytes from healthy seeds of Capsicum annuum L. and assessment of their antimicrobial activity

Isolation of yeast endophytes from healthy seeds of Capsicum annuum L. and assessment of their antimicrobial activity

New options in drug discovery: Endophyte technology

Strategy of Nematophagous Fungi in Determining the Activity of Plant Parasitic Nematodes and Their Prospective Role in Sustainable Agriculture

Contact Info

Product

Resources

About