The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-medications and Antidepressants

Bhaskar, Emmanuel; Télessy, István G.; Buttar, Harpal S.

doi:10.1007/978-981-16-9232-1_15

Cited by 1 publication

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References 135 publications

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“…Hepatic and renal impairment with comorbidities, genetic polymorphisms, and medications with a narrow therapeutic index may demonstrate high occurrences of ADR. 9 Globally, there is growing concern about the safe use of medications in hospital settings. It is well known that ADRs constitute a major problem in drug therapy and our society, both as a health care problem and as an economic burden.…”

Section: Adverse Drug Reaction Monitoring Of Commonly Prescribed Anti...mentioning

confidence: 99%

Adverse drug reaction monitoring of commonly prescribed antimicrobial agents in patients at Rama medical college, hospital and research centre, Kanpur

Princ Bgheal,

Piyush Verma,

Bhopal Chandra Vurimi

et al. 2024

Asian J Med Sci

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Background: An adverse drug reaction (ADR) is defined as a harmful or unpleasant reaction due to the use of a drug and may cause different types of effects, such as side effects. The World Health Organization states that adverse drug effects are a response to harmful and unintended medicine and occur at doses normally used in men for the prevention, diagnosis, or therapy of disease or for modifying physiological function. Aims and Objectives: The objective of the study was ADR monitoring of commonly prescribed antimicrobial agents. Materials and Methods: The study was conducted at Rama Hospital and the Research Center Mandhana Kanpur. Data were collected from the patients attending the outpatient and inpatient departments (OPD and IPD) of the medicine departments during the study period at Rama Hospital Mandhana, Kanpur. The sample size was a total of 60 patients. The study duration was conducted for 1 year. Data were collected by analyzing OPDs and IPDs in the Department of Medicine. Results: There are different types of adverse drug effects; we observed only three types of adverse drug effects in this study. The most commonly observed ADR was type A (56.66%). Out of the total ADRs reported in antimicrobial agents, skin ADRs (42.02%) and gastrointestinal tract ADRs (57.97%) are higher. There are also three different types of severity conditions observed in patients prescribed antimicrobial drugs; among them, the most commonly observed severity conditions were mild (58.33%). Conclusion: These study findings suggest that antimicrobial drugs are generally safe for most patients but can cause mild ADRs. It is important to monitor patients for ADRs while taking antimicrobial drugs and to provide appropriate treatment if necessary. Pharmacovigilance programs can help to identify and monitor ADRs, which can lead to improved patient safety.

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Section: Adverse Drug Reaction Monitoring Of Commonly Prescribed Anti...mentioning

confidence: 99%

Adverse drug reaction monitoring of commonly prescribed antimicrobial agents in patients at Rama medical college, hospital and research centre, Kanpur

Princ Bgheal,

Piyush Verma,

Bhopal Chandra Vurimi

et al. 2024

Asian J Med Sci

View full text Add to dashboard Cite

show abstract

The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-medications and Antidepressants

Cited by 1 publication

References 135 publications

Adverse drug reaction monitoring of commonly prescribed antimicrobial agents in patients at Rama medical college, hospital and research centre, Kanpur

Adverse drug reaction monitoring of commonly prescribed antimicrobial agents in patients at Rama medical college, hospital and research centre, Kanpur

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