The Importance of Assessing Nutritional Status in Elderly Patients with Heart Failure

Sargento, Luís; Longo, Susana; Lousada, Nuno; Reis, Roberto Palma dos

doi:10.1007/s11897-014-0189-5

Cited by 33 publications

(27 citation statements)

References 47 publications

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“…In the present study, the CONUT score was a useful predictor of cardiac events within 1 year after discharge in older HF patients. There is no universally accepted definition of malnutrition or a gold‐standard methodology for nutritional assessment because the interactions among age, left ventricle systolic function and clinical setting influence the evaluation of nutritional status . However, the present results showing that malnutrition assessed by CONUT score was associated with cardiac events in older patients suggest that assessment of nutritional status by CONUT score at admission might lead to earlier intervention, thus contributing to improvement in the prognosis of older HF patients.…”

Section: Discussionmentioning

confidence: 65%

Predictive factors of rehospitalization for worsening heart failure and cardiac death within 1 year in octogenarians hospitalized for heart failure

Hamada

Kubo

Yamasaki

et al. 2017

Geriatrics Gerontology Int

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Aim: To investigate the predictive factors of cardiac events including rehospitalization for worsening heart failure (HF) and cardiac death within 1 year after hospital discharge in octogenarians hospitalized for HF. Methods:We retrospectively analyzed in detail clinical data for patients aged >80 years who were admitted to Kochi University, Kochi, Japan, for acute decompensated HF in order to identify predictive factors for cardiac events within 1 year.Results: A total of 67 patients (mean age of 85 ± 4 years, 39 men) were included, and 28 patients (41.8%) had cardiac events. The patients with cardiac events were significantly older, had a lower prescription rate of beta-blockers at discharge and had a lower rate of arrhythmia as an exacerbating factor of HF than patients without cardiac events. When nutritional status was assessed by the controlling nutritional status (CONUT) score, patients in the cardiac events group had significant malnutrition (CONUT ≥5). In addition, Kaplan-Meier analysis showed that patients with CONUT ≥5 had a higher incidence of cardiac events than did those with a CONUT <5 (log-rank, P < 0.038). In logistic analysis, the independent determinants of the cardiac events within 1 year were malnutrition at moderate or severe levels by the CONUT score and no beta-blocker medication. Conclusions:In very elderly patients hospitalized for HF, malnutrition and no beta-blocker medication were predictors of rehospitalization for worsening HF or cardiac death within 1 year. These factors could be meaningful targets for improving the management of octogenarians with HF. Geriatr Gerontol Int 2017; ••: ••-••.

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Section: Discussionmentioning

confidence: 65%

Predictive factors of rehospitalization for worsening heart failure and cardiac death within 1 year in octogenarians hospitalized for heart failure

Hamada

Kubo

Yamasaki

et al. 2017

Geriatrics Gerontology Int

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“…The mechanisms by which proinflammatory cytokines, including TNF-, produced by monocytes are increased in CHF patients remain unclear. However, the production of monocyte TNF-may be enhanced by various stimuli, such as angiotensin II, CRP, and endotoxin (LPS: lipopolysaccharide) and proinflammatory cytokines, including TNF-itself [1][2][3][19][20][21] . HR: hazard ratio, C.I.…”

Section: Mechanisms Involved In the Upregulation Of Monocyte Proinflamentioning

confidence: 99%

“…Malnutrition has been identified to be an independent risk factor of morbidity and mortality in patients with chronic heart failure (CHF) 1,2) . Nutritional intervention may prevent complications and increase the quality of life in CHF patients 3,4) .…”

Section: Introductionmentioning

confidence: 99%

Nutritional Status is Associated with Inflammation and Predicts a Poor Outcome in Patients with Chronic Heart Failure

Nakagomi

Kohashi

Morisawa

et al. 2016

J Atheroscler Thromb

106

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“…Malnutrition has been recognized as an independent risk factor for morbidity and mortality in patients with chronic heart failure (CHF) 5, 6 . Some single nutritional indices such as albumin have been shown to be closely associated with poor outcomes in patients with CHF 7, 8 .…”

Section: Introductionmentioning

confidence: 99%

Prognostic nutritional index predicts clinical outcome in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Chen

et al. 2017

Sci Rep

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We aimed to investigate whether the prognostic nutritional index (PNI), a combined nutritional-inflammatory score based on serum albumin levels and lymphocyte count, was associated with mortality in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). From September 2011 to November 2014, 309 consecutive patients with STEMI undergoing pPCI were prospectively enrolled. Patients with a combined score of albumin (g/L) + 5 × total lymphocyte count × 109/L ≥ 45 or <45 were assigned a PNI score of 0 or 1, respectively. Of the 309 STEMI patients, 24 (7.74%) died in the hospital, and 15 (4.83%) died during long-term follow-up (median follow-up time, 19.5 [3–36] months). Compared to patients with a PNI of 0, patients with a PNI of 1 had significantly higher in-hospital (14.2% vs. 3.7%; P < 0.001) and long-term follow-up (21.7% vs. 6.9%, P < 0.001) mortality rates. PNI (1/0, HR, 2.414; 95% CI, 1.016 to 5.736; P = 0.046) was a significant independent predictor of mortality in patients with STEMI undergoing pPCI. Moreover, cumulative survival was significantly lower for patients with a PNI of 1 compared to patients with a PNI of 0 (78.3% vs. 93.1%, log-rank P < 0.001). PNI appears useful for the risk stratification of STEMI patients undergoing pPCI.

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The Importance of Assessing Nutritional Status in Elderly Patients with Heart Failure

Cited by 33 publications

References 47 publications

Predictive factors of rehospitalization for worsening heart failure and cardiac death within 1 year in octogenarians hospitalized for heart failure

Predictive factors of rehospitalization for worsening heart failure and cardiac death within 1 year in octogenarians hospitalized for heart failure

Nutritional Status is Associated with Inflammation and Predicts a Poor Outcome in Patients with Chronic Heart Failure

Prognostic nutritional index predicts clinical outcome in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

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