The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene

Abstract

Lycopene is a compound of colored origin that shows strong antioxidant activity. The positive effect of lycopene is the result of its pleiotropic effect. The ability to neutralize free radicals via lycopene is one of the foundations of its pro-health effect, including the ability to inhibit the development of many civilization diseases. Therefore, this study focuses on the importance of the antioxidant effect of lycopene in inhibiting the development of diseases such as cardiovascular diseases, diseases within the nervous system, diabetes, liver diseases, and ulcerative colitis. According to the research mentioned, lycopene supplementation has significant promise for the treatment of illnesses marked by chronic inflammation and oxidative stress. However, the majority of the supporting data for lycopene′s health benefits comes from experimental research, whereas the evidence from clinical studies is both scarcer and less certain of any health benefits. Research on humans is still required to establish its effectiveness.

Progress in the Use of Hydrogels for Antioxidant Delivery in Skin Wounds

“…Lycopene’s antioxidant capacity stems from its ability to neutralize free radicals and reactive oxygen species. Lycopene has a particular affinity for lipid-rich cell membranes, where it helps protect polyunsaturated fatty acids from lipid peroxidation, a key mechanism of oxidative damage [ 82 , 83 , 84 ]. There are several studies that prove the antioxidant activity of lycopene, showing its effects on diverse molecular pathways related with oxidative stress [ 85 , 86 , 87 , 88 , 89 ].…”

The Many Faces of Metabolic Dysfunction-Associated Fatty Liver Disease Treatment: From the Mediterranean Diet to Fecal Microbiota Transplantation

“…The MD is a diet characterized by low levels of saturated fat and high levels of vegetable oils. Furthermore, it contains several natural compounds with antioxidant, anti-inflammatory, antihypertensive, lipid-lowering, anti-diabetic, and anti-obesity effects [23]. For example, extra virgin olive oil with a high oleocanthal content is associated with a reduction in BMI, transaminases, and cytokines levels [22].…”

Investigation of cyclodextrin as potential carrier for lycopene

“…With other compounds in this group, it is responsible for the red and orange colour of some fruit and vegetables, such as tomato, watermelon, pink grapefruit, guava, apricot, papaya and pumpkin (1,2). In the human diet, the most common sources of this ingredient are tomatoes and tomato-based products (3). More than 85% of lycopene consumed comes from these sources (4).…”

“…Lycopene shows broad biological activity. Numerous studies show its positive effects in the prevention and amelioration of many diseases (3,13). There is growing evidence that it has beneficial effects in cardiovascular disease, cancer, diabetes, liver disease, neurological diseases and other disorders (1,14).…”