The importance, benefits, and future of nanobiosensors for infectious diseases

Abstract

Infectious diseases, caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi, are crucial for efficient disease management, reducing morbidity and mortality rates and controlling disease spread. Traditional laboratory‐based diagnostic methods face challenges such as high costs, time consumption, and a lack of trained personnel in resource‐poor settings. Diagnostic biosensors have gained momentum as a potential solution, offering advantages such as low cost, high sensitivity, ease of use, and portability. Nanobiosensors are a promising tool for detecting and diagnosing infectious diseases such as coronavirus disease, human immunodeficiency virus, and hepatitis. These sensors use nanostructured carbon nanotubes, graphene, and nanoparticles to detect specific biomarkers or pathogens. They operate through mechanisms like the lateral flow test platform, where a sample containing the biomarker or pathogen is applied to a test strip. If present, the sample binds to specific recognition probes on the strip, indicating a positive result. This binding event is visualized through a colored line. This review discusses the importance, benefits, and potential of nanobiosensors in detecting infectious diseases.

Advances in Detecting Cystic Echinococcosis in Intermediate Hosts and New Diagnostic Tools: A Literature Review

“…It is crucial to develop nanobiosensors capable of detecting subtle genetic variations, and these special features have been reported in the medical oncology field [ 115 ]. Developing high-specificity nanobiosensors and understanding the parasite’s genetic landscape is essential [ 116 ]. For CE control programs to be effective, robust surveillance systems must exist.…”

Breaking boundaries in microbiology: customizable nanoparticles transforming microbial detection

“…Nanobiosensing systems have gained substantial interest in bacterial detection due to their high sensitivity, easy operation, shorter analysis time, and low cost. 37 Different kinds of nanobiosensors, such as fabricated strips embedded with nanoparticles, nanocomposites decorated with spongins, multi-probe genomic biosensors, and nanocomposites-modified carbon screen-printed electrodes have already been shown to be extremely successful in bacterial cell detection. 38–40…”