The implications of ortho-, meta- and para- directors on the in-vitro photodynamic antimicrobial chemotherapy activity of cationic pyridyl-dihydrothiazole phthalocyanines

Magadla, Aviwe; Openda, Yolande Ikala; Nyokong, Tebello

doi:10.1016/j.pdpdt.2022.103029

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Pcs Combined With Nanoparticles1

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2023

2024

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Cited by 3 publications

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“…As a result, the antimicrobial activity of ZnPc@SiNPs‐GA was increased compared to that of ZnPc alone. This study confirmed that ZnPcs bearing a total of 8 cationic charges exhibited enhanced bactericidal activity compared to those with no charge or 4 charges [28] …”

Section: Pcs Combined With Nanoparticlessupporting

confidence: 73%

Phthalocyanine‐Based Photosensitizers for Photodynamic Antibacterial Therapy

Zhou,

Zheng,

et al. 2024

ChemistrySelect

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Bacterial infection poses a grave peril to human existence and well‐being, particularly with the emergence of drug‐resistant bacteria, leading to an alarming rise in the incidence of severe illness and mortality. Antimicrobial photodynamic therapy (aPDT) has emerged as one of the most promising strategies for combating bacterial infections due to its potent bactericidal efficacy and non‐inducement of resistance. The development of novel photosensitizers represents a viable approach to further enhance the efficacy of aPDT. Hence, the structural design and application strategies of phthalocyanine‐based photosensitizers were summarized to provide guidance in the development of highly efficient aPDT agents.

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Section: Pcs Combined With Nanoparticlessupporting

confidence: 73%