The impact of written information and counseling (WOMAN-PRO II Program) on symptom outcomes in women with vulvar neoplasia: A multicenter randomized controlled phase II study

Raphaelis, Silvia; Mayer, Hanna; Ott, Stefan; Mueller, Michael D.; Steiner, Enikö; Joura, Elmar A.; Senn, Beate

doi:10.1016/j.ygyno.2017.04.024

Cited by 4 publications

(7 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During the follow-up phase a total of thirteen women (26.5%) dropped out, primarily because they were no longer available after being transferred to another hospital. The process of patient recruitment, randomization and follow-up is presented in the publication of the primary outcomes [15].…”

Section: Resultsmentioning

confidence: 99%

“…The primary outcome of this study was the symptom prevalence in women with vulvar neoplasia over six months after surgical treatment. Results focusing on this outcome are published elsewhere [15].…”

Section: Methodsmentioning

confidence: 99%

“…Participants in intervention I received standard care and written information, while participants in intervention II additionally received systematic counseling by an APN with a focus on promoting self-management of post-surgical symptoms. A detailed description of the interventions can be found in a prior study [15].…”

Section: Interventionsmentioning

confidence: 99%

See 2 more Smart Citations

The effect of written information and counseling by an APN on resilience in women with vulvar neoplasia during six months after surgical treatment and the influence of social support, recurrence, and age: A secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO-II

Kofler

Kobleder

Ott

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

Background Woman with vulvar neoplasia complain after surgical treatment often about physical and psychological distress. Lack of information and support can influence resilience. Whether an information-related intervention through an advanced practice nurse support resilience and which other factors have an influence on resilience in women with vulvar neoplasia has never been investigated.Methods The aim of this study were (a) to analyse whether counseling based on the WOMAN-PRO-II program compared to written information creates a significant improvement in resilience scores of women with vulvar neoplasia and (b) to identify potential predictors for resilience. A randomized controlled trial was carried out in women with vulvar neoplasia (N = 49) six months after a surgical treatment in four Swiss hospitals and one Austrian hospital. Analyses of resilience and its predictors were performed using a linear mixed model.Results The resilience score did not differ significantly between the two intervention three and six months after randomisation (p=0.759). As significant predictors of resilience, age (b=.04, p=0.001), social support (b=.28, p=0.009), counseling time (b=.03, p=0.018), and local recurrence (b=-.56, p=0.009) could be identified in linear mixed models analyses.Conclusion To promote resilience in women with vulvar neoplasia, the WOMAN-PRO II Program should be further developed. Particularly, social support should be extended, e.g. in form of more frequent consultations. The interrelation between recurrence and resilience needs to be further investigated to provide specific counseling for women with recurrence.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

The effect of written information and counseling by an APN on resilience in women with vulvar neoplasia during six months after surgical treatment and the influence of social support, recurrence, and age: A secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO-II

Kofler

Kobleder

Ott

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…The primary outcome was the symptom prevalence in women with vulvar neoplasia over months after surgical treatment. Results focusing on this outcome are published elsewhere [20].…”

Section: Methodsmentioning

confidence: 99%

“…The assessments of symptoms and distress are discussed in the APN consultation, focusing on tailored information, motivational interviewing, self-management and behavioural change. A detailed description of the interventions can be found in a previous study [20].…”

Section: Interventionsmentioning

confidence: 99%

The effect of written information and counselling by an advanced practice nurse on resilience in women with vulvar neoplasia six months after surgical treatment and the influence of social support, recurrence, and age: a secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO II

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background: Women with vulvar neoplasia often complain about physical and psychological distress after surgical treatment. Lack of information and support can influence resilience. Whether an information-related intervention through an advanced practice nurse supports resilience and which other factors affect resilience in women with vulvar neoplasia has never been investigated. Methods: The aims of this study were (a) to analyse whether counselling based on the WOMAN-PRO II program causes a significant improvement in the resilience scores of women with vulvar neoplasia compared to written information and (b) to identify the potential predictors of resilience. A randomized controlled trial was conducted in women with vulvar neoplasia (n = 49) 6 months after surgical treatment in four Swiss hospitals and one Austrian hospital. Analyses of resilience and its predictors were performed using a linear mixed model.

show abstract

Pre-operative hypoalbuminemia is associated with complication rate and overall survival in patients with vulvar cancer undergoing surgery

Bekos

Polterauer

Seebacher

et al. 2019

Arch Gynecol Obstet

Self Cite

View full text Add to dashboard Cite

ObjectiveHypoalbuminemia, a known marker for malnutrition, has been associated with an increased risk for perioperative morbidity and poor prognosis in patients with solid tumors. The aim of this study was to investigate the prognostic and predictive value of pre-treatment serum albumin levels for survival and postoperative complications in patients with vulvar cancer undergoing surgery.MethodsWithin in this retrospective study, we assessed data of 103 consecutive patients with vulvar cancer undergoing primary surgery into this study. Pre-treatment serum albumin levels were correlated with clinico-pathological parameters and complications. We performed univariate log-rank test and multivariable Cox regression models to evaluate the association between pre-treatment serum albumin and survival.ResultsWe found hypoalbuminemia (< 35 mg/dl) in 9 of 103 (8.7%) patients. No difference in tumor characteristics was observed between patients with hypoalbuminemia and normal serum albumin levels. Difference in postoperative complications (55.6% and 37.8% of patients with hypoalbuminemia and normal serum albumin levels, respectively) was not statistically significant (p = 0.345). Shorter overall survival (OS) was observed in patients with hypoalbuminemia (5-year OS rate 17.1%) when compared to patients with normal serum albumin levels (5-year OS rate 58.6%, p = 0.004). In multivariable analysis, age (p = 0.017), FIGO stage (p = 0.011) and serum albumin levels (p = 0.013) were independently associated with OS.ConclusionPre-treatment hypoalbuminemia is an independent prognostic biomarker for OS in patients with vulvar cancer. We did not find an association between pre-treatment hypoalbuminemia and a higher risk for postoperative complications.Electronic supplementary materialThe online version of this article (10.1007/s00404-019-05278-7) contains supplementary material, which is available to authorized users.

show abstract

The impact of written information and counseling (WOMAN-PRO II Program) on symptom outcomes in women with vulvar neoplasia: A multicenter randomized controlled phase II study

Cited by 4 publications

References 35 publications

The effect of written information and counseling by an APN on resilience in women with vulvar neoplasia during six months after surgical treatment and the influence of social support, recurrence, and age: A secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO-II

The effect of written information and counseling by an APN on resilience in women with vulvar neoplasia during six months after surgical treatment and the influence of social support, recurrence, and age: A secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO-II

The effect of written information and counselling by an advanced practice nurse on resilience in women with vulvar neoplasia six months after surgical treatment and the influence of social support, recurrence, and age: a secondary analysis of a multicenter randomized controlled trial, WOMAN-PRO II

Pre-operative hypoalbuminemia is associated with complication rate and overall survival in patients with vulvar cancer undergoing surgery

Contact Info

Product

Resources

About