The Impact of Vulvar Lichen Sclerosus on Sexual Dysfunction

Haefner, Hope K.; Aldrich, Nely Z.; Dalton, Vanessa K.; Gagné, Hélène; Marcus, Stephanie B.; Patel, Divya; Berger, Mitchell B.

doi:10.1089/jwh.2014.4805

Cited by 76 publications

(68 citation statements)

References 28 publications

(32 reference statements)

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“…Women with VLS experience significant sexual dysfunction and distress, as well as somatic symptoms and emotional distress, with a significant overall impact on health‐related quality of life . However, this impact is infrequently measured in routine clinical practice as demonstrated by Simpson and colleagues .…”

Section: Discussionmentioning

confidence: 99%

The Vulval Disease Quality of Life Index in women with vulval lichen sclerosus correlates with clinician and symptom scores

et al. 2019

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Background/Objectives: The Vulval diseaseQuality of Life Index (VQLI) is a new tool that assesses the burden of vulval disease on quality of life (QoL). Our objective was to assess the correlation between VQLI score and clinician-rated severity scores, overall patient itch/discomfort, disease duration, sexual activity, and age, in vulval lichen sclerosus (VLS) at a vulval disorders clinic.Methods: A retrospective case note review, including consecutive women with VLS who attended the clinic between April and October 2018. Outcome measures include the VQLI score, clinician-rated severity score, and patient symptom score.Results: A total of 109 women with VLS were included. On multivariable analysis, there was evidence of a positive relationship between VQLI scores and the total clinician-rated score (mean increase in VQLI score per unit increase in clinician score 1.34, 95% confidence interval [CI] 0.31, 2.38; P = 0.01); the relationship was stronger for the cutaneous component. There was little evidence for relationships of the VQLI with the patient's age, sexual activity or time since onset of symptoms. There was strong evidence for a positive relationship between VQLI score and overall itch/discomfort score (mean increase 2.38, 95% CI 1.88, 2.88; P < 0.001). New and followup data were obtained on sequential visits for 12 women, among whom the VQLI score dropped a mean À2.75 points between visits (95% CI À6.05, 0.55; P = 0.094). Conclusion:The clinician-rated severity correlates with the impact of VLS on QoL. The VQLI captures information included in a patient itch/discomfort score, which can be easily incorporated into routine assessment.

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Section: Discussionmentioning

confidence: 99%

The Vulval Disease Quality of Life Index in women with vulval lichen sclerosus correlates with clinician and symptom scores

et al. 2019

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“…VLS and SCHV may cause significant vulvar changes affecting the quality of life. It is plausible that anatomical changes resulting from them -especially from VLS -may result in sexual dysfunction 15 . Both of them have malignant potential: 3 to 6% for VLS, and 2 to 4% for SCHV 1 .…”

Section: Discussionmentioning

confidence: 99%

Treatment of vulvar leukoplakia with Theresienol

Yordanov¹,

Vasileva²,

Strashilov³

et al. 2019

Arch Balk Med Union

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Le traitement de la leucoplasie vulvaire à l'huile de Thérèse-une nouvelle perspective Introduction. La leucoplasie vulvaire n'est pas un diagnostic histologique et comprend plusieurs conditions. Les plus communes d'entre elles sont le lichen scléreux vulvaire et l'hyperplasie squameuse de la vulve. Ces deux conditions présentent de nombreuses caractéristiques en commun, mais également de grandes différences. Dans les deux cas il y a le risque de malignité ou de rechute de la maladie après un traitement avisé curatif. Rapport du cas. Nous présentons quatre patients avec un diagnostic clinique de leucoplasie vulvaire, traités à l'huile de Thérèse. Tous les patients avaient leur traitement durant deux à trois mois et ils étaient en suivi pendant un an après. Le lichen scléreux et l'hyperplasie squameuse vulvaire ont d'étiologie similaire, ainsi que des signes et symptômes cliniques. Ils ont aussi des particularités histopathologiques qui nécessitent également de traitements différents-conservatif ou par chirurgie. Toutes les options thérapeutiques

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“…The most common disorders triggering sexual dysfunction are vulvar infections, lichen and vulvodynia. Women with vulvar disorders have less frequent and less satisfying sexual activity [40,41].…”

Section: Impact Of Vulvar Disorders On Sexual Functionmentioning

confidence: 99%