2023
DOI: 10.1007/s10237-023-01742-1
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The impact of vascular volume fraction and compressibility of the interstitial matrix on vascularised poroelastic tissues

Pietro Mascheroni,
Raimondo Penta,
José Merodio

Abstract: In this work we address the role of the microstructural properties of a vascularised poroelastic material, characterised by the coupling between a poroelastic matrix and a viscous fluid vessels network, on its overall response in terms of pressures, velocities and stress maps. We embrace the recently developed model (Penta and Merodio in Meccanica 52(14):3321–3343, 2017) as a theoretical starting point and present the results obtained by solving the full interplay between the microscale, represented by the int… Show more

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Cited by 3 publications
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“…In this work, we have assumed a rigid porous matrix to keep the model as simple as possible and due to the lack of biological data regarding this problem; a possible extension of this model is to take into account a deformable matrix that interacts with the lymph flow inside the node, for example by considering the modelling framework developed in [ 91 , 92 ].…”
Section: Discussionmentioning
confidence: 99%
“…In this work, we have assumed a rigid porous matrix to keep the model as simple as possible and due to the lack of biological data regarding this problem; a possible extension of this model is to take into account a deformable matrix that interacts with the lymph flow inside the node, for example by considering the modelling framework developed in [ 91 , 92 ].…”
Section: Discussionmentioning
confidence: 99%