The impact of transcutaneous electrical stimulation therapy on appendicostomy operation rates for children with chronic constipation—a single-institution experience

Yik, Yee Ian; Leong, L.C.Y.; Hutson, John M.; Southwell, Bridget R.

doi:10.1016/j.jpedsurg.2012.01.017

Cited by 20 publications

(19 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It accounts for 3-5 % of visits to pediatricians and 10-25 % to pediatric gastroenterologists [7]. About 30 % of Dutch children continue to have ORIS throughout adolescence.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Contrast enema as a guide for senna-based laxatives in managing overflow retentive stool incontinence in pediatrics

2015

View full text Add to dashboard Cite

show abstract

“…It accounts for 3-5 % of visits to pediatricians and 10-25 % to pediatric gastroenterologists [7]. About 30 % of Dutch children continue to have ORIS throughout adolescence.…”

Section: Discussionmentioning

confidence: 99%

“…The aim of the treatment is to achieve and maintain regular bowel movements free of symptoms [1,6]. Laxatives remain the mainstay of maintenance therapy of ORSI; yet, there is no standard laxative therapy despite the varieties of medication currently available [7].…”

Section: Introductionmentioning

confidence: 99%

Contrast enema as a guide for senna-based laxatives in managing overflow retentive stool incontinence in pediatrics

2015

View full text Add to dashboard Cite

show abstract

“…Nevertheless, several studies have used the same frequencies and device (EPM IF 4160 Fuji Dynamics Ltd, Kowloon, Hong Kong). 52 In these studies, a 4-kHz carrier frequency is selected with a beat frequency sweep of 80-160 Hz with a variable intensity of < 33 mA in adults. The beat frequency sweep varied in pediatric studies from 80-120 Hz to 80-150 Hz.…”

Section: Discussionmentioning

confidence: 99%

Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Moore

Burgell

2018

J Neurogastroenterol Motil

View full text Add to dashboard Cite

The concept of therapeutic percutaneous neuromodulation has, until recently, been limited by the ability to penetrate deeply enough to stimulate internal organs. By utilizing 2 medium frequency, slightly out of phase electrical currents passing diagonally through the abdomen, a third, low frequency current is created at the point of bisection. This interferential current appears to stimulate nerve fibers in the target organs and may have a therapeutic action. The aim of the study is to review the use of transcutaneous interferential electrical stimulation with a focus on its application in gastroenterology, particularly in motility disorders. Studies involving use of interferential current therapy were searched from Medline, PubMed, and Scopus databases, and articles pertaining to history, its application and all those treating abdominal and gastrointestinal disorders were retrieved. Seventeen studies were identified, 13 involved children only. Eleven of these were randomised controlled trials (3 in adults). Four trials were from the one center, where each paper reported on different outcomes such as soiling, defecation frequency, quality of life, and colon transit studies from the one pool of children. All studies found statistically significant improvement in symptom reduction. However, weaknesses in study design were apparent in some. In particular, finding an adequate placebo to interferential current therapy has been difficult. Interferential current therapy shows potential as a novel, non-pharmacological and economical means of treating gastrointestinal dysfunction such as constipation. More studies are needed particularly in the adult population. However, the design of a suitable placebo is challenging. Search MethodA search of Medline, PubMed, and Scopus databases for information on electrical interferential current and its application using search words such as "electrical interferential current," "transcutaneous," "therapeutics or uses," "mechanisms of action," and "gastrointestinal" was performed. Articles that were available in English were included. This review focuses on the use of transcutaneous interferential current therapy in the treatment of gastrointestinal symptoms. The Nature of Interferential Current TherapyInterferential current therapy has been used in a variety of settings including low back pain 11 and neurological disorders such as carpal tunnel syndrome. 12 More recently, interferential current therapy has been found to be effective in small studies in managing conditions such as fecal incontinence and constipation. It has the benefit of being completely non-invasive, cost effective and convenient, as it can be self-administered at home. 13Despite increased convenience to the patient, doctor and payer, the use of transcutaneously-delivered current can be problematic. To stimulate the nerve of interest, the current has to pass through the skin and surrounding muscle to reach its target. This causes resistance to flow, requiring the use of a higher current to achieve the desired resu...

show abstract

“…Since 2006, appendicostomy-formation rates at our institute have significantly reduced in STC but not in non-STC children, coinciding with the introduction of TES as an alternative treatment for STC [48]. Transcutaneous electrical stimulation has not been tested on non-STC children in this period.…”

Section: Box 1 Effects Of Tes In Patients In Stcmentioning

confidence: 99%

Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

et al. 2015

Self Cite

View full text Add to dashboard Cite

Slow-transit constipation (STC) is a newly described subtype of intractable constipation in children which we originally identified with deficiency of substance P in axons supplying the proximal colonic muscle. When nuclear transit studies became available, the patients were found to have slow proximal colonic transit, and responded to antegrade enemas. Using the appendicostomy, we found that there was reduced frequency in propagating sequences throughout the colon. We began testing whether transcutaneous electrical stimulation (TES) could improve motility and symptoms, and over several trials have now shown that TES is remarkably effective in treating children with STC, with long-lasting effects. TES holds promise for treating STC, as well as a range of gastrointestinal motility disorders.

show abstract

The impact of transcutaneous electrical stimulation therapy on appendicostomy operation rates for children with chronic constipation—a single-institution experience

Cited by 20 publications

References 62 publications

Contrast enema as a guide for senna-based laxatives in managing overflow retentive stool incontinence in pediatrics

Contrast enema as a guide for senna-based laxatives in managing overflow retentive stool incontinence in pediatrics

Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

Contact Info

Product

Resources

About