The impact of tinnitus upon cognition in adults: A systematic review

Tegg-Quinn, Susan; Bennett, Rebecca J.; Eikelboom, Robert H.; Baguley, David

doi:10.1080/14992027.2016.1185168

Cited by 98 publications

(102 citation statements)

References 60 publications

(134 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Tinnitus impairs cognitive function because of its impact on the control of attention [37]. To assess proneness to committing cognitive slips and errors in the completion of everyday tasks, such as failures in perception, memory and motor function, the Cognitive Failures Questionnaire [38] will be included.…”

Section: Methodsmentioning

confidence: 99%

Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial

Beukes

Baguley

Allen

et al. 2017

Trials

Self Cite

View full text Add to dashboard Cite

BackgroundInnovative strategies are required to improve access to evidence-based tinnitus interventions. A guided Internet-based cognitive behavioural therapy (iCBT) intervention for tinnitus was therefore developed for a U.K. population. Initial clinical trials indicated efficacy of iCBT at reducing tinnitus severity and associated comorbidities such as insomnia and depression. The aim of this phase III randomised controlled trial is to compare this new iCBT intervention with an established intervention, namely face-to-face clinical care for tinnitus.Methods/designThis will be a multi-centre study undertaken across three hospitals in the East of England. The design is a randomised, two-arm, parallel-group, non-inferiority trial with a 2-month follow-up. The experimental group will receive the guided iCBT intervention, whereas the active control group will receive the usual face-to-face clinical care. An independent researcher will randomly assign participants, using a computer-generated randomisation schedule, after stratification for tinnitus severity. There will be 46 participants in each group. The primary assessment measure will be the Tinnitus Functional Index. Data analysis will establish whether non-inferiority is achieved using a pre-defined non-inferiority margin.DiscussionThis protocol outlines phase III of a clinical trial comparing a new iCBT with established face-to-face care for tinnitus. If guided iCBT for tinnitus proves to be as effective as the usual tinnitus care, it may be a viable additional management route for individuals with tinnitus. This could increase access to evidence-based effective tinnitus care and reduce the pressures on existing health care systems.Trial registrationClinicalTrials.gov identifier: NCT02665975. Registered on 22 January 2016.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-017-1931-6) contains supplementary material, which is available to authorized users.

show abstract

Section: Methodsmentioning

confidence: 99%

Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial

Beukes

Baguley

Allen

et al. 2017

Trials

Self Cite

View full text Add to dashboard Cite

show abstract

“…To date, there are three reviews with each having a slightly different focus (Andersson and McKenna, 2006; Mohamad et al, 2016; Tegg-Quinn et al, 2016). …”

Section: Introductionmentioning

confidence: 99%

“…Recently Tegg-Quinn et al (2016) performed a similar systematic review, however, with a broader search criterion and a focus on clinical management of invasive tinnitus. They report 18 studies employing a variety of measures on cognitive functions in tinnitus.…”

Section: Introductionmentioning

confidence: 99%

Impairments of Speech Comprehension in Patients with Tinnitus—A Review

Ivanšić

Guntinas‐Lichius

Müller

et al. 2017

Front. Aging Neurosci.

View full text Add to dashboard Cite

Tinnitus describes the subjective perception of a sound despite the absence of external stimulation. Being a sensory symptom the majority of studies focusses on the auditory pathway. In the recent years, a series of studies suggested a crucial involvement of the limbic system in the manifestation and development of chronic tinnitus. Regarding cognitive symptoms, several reviews addressed the presence of cognitive impairments in tinnitus as well and concluded that attention and memory processes are affected. Despite the importance for social communication and the reliance on a highly functional auditory system, speech comprehension remains a largely neglected field in tinnitus research. This is why we review here the existing literature on speech and language functions in tinnitus patients. Reviewed studies suggest that speech comprehension is impaired in patients with tinnitus, especially in the presence of competing noise. This is even the case in tinnitus patients with normal hearing thresholds. Additionally, speech comprehension measures seem independent of other measures such as tinnitus severity and perceived tinnitus loudness. According to the majority of authors, the speech comprehension difficulties arise as a result of central processes or dysfunctional neuroplasticity.

show abstract

“…Diagnosis primarily relies on self-report, yet because the impact of tinnitus can be so varied from one patient to another, how it is best treated in individuals is still unclear (5). For example, some patients can complain primarily from sleeping problems (6), or from impaired cognitive function (7, 8) or from communication disabilities (9). Tinnitus is a highly unmet clinical need and there are still no singularly effective therapies that reliably reduce tinnitus percept or its symptoms (10–13).…”

Section: Introductionmentioning

confidence: 99%

Visualization of Global Disease Burden for the Optimization of Patient Management and Treatment

et al. 2017

View full text Add to dashboard Cite

BackgroundThe assessment and treatment of complex disorders is challenged by the multiple domains and instruments used to evaluate clinical outcome. With the large number of assessment tools typically used in complex disorders comes the challenge of obtaining an integrative view of disease status to further evaluate treatment outcome both at the individual level and at the group level. Radar plots appear as an attractive visual tool to display multivariate data on a two-dimensional graphical illustration. Here, we describe the use of radar plots for the visualization of disease characteristics applied in the context of tinnitus, a complex and heterogeneous condition, the treatment of which has shown mixed success.MethodsData from two different cohorts, the Swedish Tinnitus Outreach Project (STOP) and the Tinnitus Research Initiative (TRI) database, were used. STOP is a population-based cohort where cross-sectional data from 1,223 non-tinnitus and 933 tinnitus subjects were analyzed. By contrast, the TRI contained data from 571 patients who underwent various treatments and whose Clinical Global Impression (CGI) score was accessible to infer treatment outcome. In the latter, 34,560 permutations were tested to evaluate whether a particular ordering of the instruments could reflect better the treatment outcome measured with the CGI.ResultsRadar plots confirmed that tinnitus subtypes such as occasional and chronic tinnitus from the STOP cohort could be strikingly different, and helped appreciate a gender bias in tinnitus severity. Radar plots with greater surface areas were consistent with greater burden, and enabled a rapid appreciation of the global distress associated with tinnitus in patients categorized according to tinnitus severity. Permutations in the arrangement of instruments allowed to identify a configuration with minimal variance and maximized surface difference between CGI groups from the TRI database, thus affording a means of optimally evaluating the outcomes in individual patients.ConclusionWe anticipate such a tool to become a starting point for more sophisticated measures in clinical outcomes, applicable not only in the context of tinnitus but also in other complex diseases where the integration of multiple variables is needed for a comprehensive evaluation of treatment response.

show abstract

The impact of tinnitus upon cognition in adults: A systematic review

Cited by 98 publications

References 60 publications

Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial

Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial

Impairments of Speech Comprehension in Patients with Tinnitus—A Review

Visualization of Global Disease Burden for the Optimization of Patient Management and Treatment

Contact Info

Product

Resources

About