The Impact of Tinnitus on Fibromyalgia

Chung, Chong Hyuk; Jang, Gyuho

doi:10.4078/jrd.2021.28.1.31

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…Similarly, Chung et al [21] demonstrated that 46.8% and 87.2% of the 47 FM patients had tinnitus and headache, respectively, suggesting a high incidence of these symptoms in FMS. They proposed that tinnitus is an important aspect of centrally related symptoms in FM, implying that the degree of tinnitus corresponds directly to the severity of FM and should be investigated in all FM patients.…”

Section: Discussionmentioning

confidence: 83%

Assessment of Audiovestibular function in Fibromyalgia Patients

Essam,

Nada,

Koura

et al. 2023

Egyptian Journal of Ear, Nose, Throat and Allied Sciences

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Introduction: Fibromyalgia(FM)is a chronic pain syndrome characterized by generalized muscle pain.Despite of disease severity, several neurological symptoms including tinnitus, ear fullness, vertigo, and dizziness could be related. Purpose: Evaluation of the audio-vestibular function in patients diagnosed with fibromyalgia. Methods: The Study group involved sixty patients with fibromyalgia and the control group composed of sixty healthy individuals with age and gender matching to the study group. Pure tone audiometry, auditory brainstem-evoked potential test, cervical and ocular vestibular evoked myogenic potential (cVEMP and oVEMP), videonystagmography test (VNG)were done. Fall risk assessment of fibromyalgia patients was done by arabic version of Short Falls Efficacy Scale-International (FES-I). Results: Mean hearing thresholds were significantly higher in cases at 250Hz, 4000Hz, and 8000Hz than in controls. The latencies of I, III, V, I-III, I-V and III-V waves were statistically significant prolonged in FM patients than the control.Also, patients with FM had statistically significant longer P13 and N23 latencies than the control group and significantly lower IP amplitude as regard cVEMP results. FES-I revealed that 16 (26.7%) of FM patients had low concern, 40 (66.7%) had moderate concern, and 4 (6.7%) had high concern. Conclusion: FM was found to be associated with a high incidence of sensorineural hearing loss. Impairment of ABR, c VEMP and o VEMP indicate both auditory and vestibular system involvements. The hearing and balance functions work in combination and should be tested concurrently in systemic disorders such as fibromyalgia.

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Section: Discussionmentioning

confidence: 83%

Assessment of Audiovestibular function in Fibromyalgia Patients

Essam,

Nada,

Koura

et al. 2023

Egyptian Journal of Ear, Nose, Throat and Allied Sciences

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“…Preliminary data suggest a higher handicap relating to the presence of dizziness in patients with fibromyalgia compared to controls [49]. Furthermore, a recent, small-scale cross sectional study of the impact of tinnitus in fibromyalgia provides preliminary support for the link with central sensation as the severity of tinnitus was associated with severity of overall symptoms of fibromyalgia, and poorer quality of life [15]. Self-reported hearing loss, amongst other sensory symptoms, has also been previously shown to be more prevalent amongst patients with fibromyalgia compared to those with other rheumatic conditions, adjusting for age and sex [67].…”

Section: Discussionmentioning

confidence: 99%

Talking about diseases; developing a model of patient and public-prioritised disease phenotypes

Slater,

Schofield,

Wright

et al. 2023

Preprint

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BackgroundDeep phenotyping describes the use of formal and standardised terminologies to create comprehensive phenotypic descriptions of biomedical phenomena. While most often employed to describe patients, phenotype models may also be developed to characterise diseases. These characterisations facilitate secondary analysis, evidence synthesis, and practitioner awareness, thereby guiding patient care. The vast majority of this knowledge is derived from sources that describe an academic understanding of disease, including academic literature and experimental databases. Previous work has revealed a gulf between the priorities, perspectives, and perceptions held by healthcare researchers and providers and the users of clinical services. A comparison between canonical disease descriptions and phenotype models developed from public discussions of disease offers the prospect of discovery of new phenotypes, patient population stratification, and targeted mitigation of symptoms most damaging to patients quality of life.MethodsUsing a dataset representing disease and phenotype co-occurrence in social media text, we employ semantic techniques to identify phenotype associations for a set of common and rare diseases, constituting a phenotype model for those diseases that represents the public perspective. We create an integrated resource for biomedical database and literature-derived disease-phenotype associations by aligning data from several previous studies. We then explore differences between the disease-phenotype associations derived from writing in social media with those from the clinical literature and biomedical databases, with a focus on identification of differential themes and novel phenotypes. We also perform an evaluation of associations for several diseases, with specialist clinicians reviewing associations for validity, feasibility, and involvement in clinical care.FindingsWe identified 35,782 significant disease-phenotype associations from social media across 311 diseases, of which 304 could be linked to a combined resource of associations derived from academic sources. Social media-derived disease profiles recapitulated those from academic sources (AUC=0.874 (.95=0.858-0.891)). We further identified 26,081 novel phenotype associations that were not contained in the academic sources, of which 15,084 were considered significant. Constitutional symptoms, those holistic manifestations of disease affecting quality of life, were strongly over-represented in the social media phenotype, contributing more associations especially to endocrine, digestive, and reproductive diseases. An expert clinical review found that social media-derived associations were considered similarly well-established to those derived from literature, and were seen significantly more in patient clinical encounters.InterpretationThe phenotype model recovered from social media presents a significantly different perspective than existing resources derived from biomedical databases and literature, providing a large number of associations novel to the latter dataset. We propose that the integration and interrogation of these public perspectives on disease can inform clinical awareness, improve secondary analysis, and bridge understanding across healthcare stakeholders.

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“…Туа біткен даму ақаулар жалғыз немесе қосарланған болуы мүмкін және олар аса маңызды немесе аз клиникалық мәнге ие. Жаңа туылған нәрестелердің шамамен 14% -ында жалғыз шағын ақаулар байқалатындығы дәлелденген [5]. Италияндық ғалым Р.Бертоллинидің зерттеуінде «барлық жүктіліктің шамамен 40% жүктіліктің алғашқы екі аптасында түсік тастаумен аяқталатыны анықталды, тағы 10% жүктілік жүктіліктің 70-ші күніне дейін өздігінен түсік түсірумен аяқталады.…”

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Туа Біткен Даму Ақаулардың Алдын Алу Және Диагностикасының Проблемалық Мәселелері

АЯЗБЕКОВ,

НУРХАСИМОВА,

ОШИБАЕВА

et al. 2023

Farmaciâ Kazahstana

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Мақалада авторлар қазіргі уақытта әлемнің көптеген елдерінде туа біткен даму ақауларлар қоғамдық денсаулық сақтау саласының өзекті мәселесі болып қала беретін және бала өлімі мен мүгедектік қаупіне маңызды фактор болып табылатын даму ақауларын зерттейді. Түркістан облысы №3 Облыстық перинаталды орталықта жүкті және босанушы әйелдердің босану тарихын, алмасу картасын, нәрестелер даму тарихын және жеке картасын қолдана отырып, 2020-2022 жылдар аралығында ретроспективті салыстырмалы талдау жүргізілді, зерттеу объектілері тірі туылған тума ақаулары бар 269 нәресте болды. 2020-2022 жылдар аралығында жалпы дүниеге келген тірі туылған нәрестелер саны 31724 (100%), оның ішінде туа біткен даму ақаумен туылған нәрестелер үлесі 269 (0.84%) нәресте екені анықталды. Соңғы үш жылда орталықта туа біткен даму ақауымен туылған нәрестелер жиілігі 1.8 есеге немесе 47.1%- ға артқандығын зерттеу барысында айқындалды. Осы жылдар ағымында жүйелер бойынша, яғни, жүрек тамыр жүйесі 1.05%-ға, тыныс алу жүйесі 0.78%- ға, ас қорыту жүйесі 0.94%-ға, зәр шығару жүйесі 0.78%-ға, орталық жүйке жүйесі 1.42%-ға, тірек қимыл аппараты ақауы 1.19%-ға, сезім мүшелер ақауы 1.05%-ға, сонымен қатар хромосомдық ақау 0.78%-ға артқандығы, ал керісінше ерін және таңдай жарығы 0.49%-ға кемігендігі белгілі болды. Туа біткен даму ақаулардың жоғары деңгейі олардың алдын алу шараларын әзірлеу мен жүзеге асыруды қажет етеді.

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The Impact of Tinnitus on Fibromyalgia

Cited by 5 publications

References 20 publications

Assessment of Audiovestibular function in Fibromyalgia Patients

Assessment of Audiovestibular function in Fibromyalgia Patients

Talking about diseases; developing a model of patient and public-prioritised disease phenotypes

Туа Біткен Даму Ақаулардың Алдын Алу Және Диагностикасының Проблемалық Мәселелері

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