The impact of the COVID-19 pandemic on the Management of Locally Advanced Primary/Recurrent Rectal Cancer

Chok, Aik Yong; Kontovounisios, Christos; Rasheed, Shahnawaz; Kelly, Michael E.; AGJ, Aalbers; Aziz, Nauman; Abecasis, Nuno; Abraham-Nordling, Mirna; Akiyoshi, Takashi; Alberda, Wijnand J.; Albert, Matthew L.; Andric, Mihailo; Angenete, Eva; Antoniou, A; Auer, R; Austin, Kirk K. S.; Aziz, Omer; Baker, R. P.; Bali, M; Baseckas, Gediminas; Bebington, Brendan; Bedford, Matthew; Bednarski, Brian Keith; Beets, Geerard L.; Berg, P L; Beynon, J; Biondo, Sebastiano; Boyle, K; Bordeianou, L; Bremers, A B; Brunner, Markus; Buchwald, Pamela; Bui, Ai-Tram N.; Burgess, Andrea; Jwa, Burger; Burling, D; Burns, Elaine; Campain, Nicholas; Carvalhal, Sara; Castro, Luis M.; Caycedo‐Marulanda, Antonio; Chan, Kkl; Chang, George J.; Chang, Matthew Wook; Chew, Min Hoe; Chong, Patrick; Christensen, Henrik; Clouston, H; Codd, Mary; Collins, Debra L.; Colquhoun, A J; Corr, Alison; Coscia, Maurizio; Cosimelli, Maurizio; Coyne, Peter; Creavin, Ben; Croner, Roland S.; Damjanovic, L; Daniels, Ian; Davies, Michael M.; Davies, Rsm; Delaney, Clare; JHW, de Wilt; Denost, Quentin; Deutsch, C; Dietz, D.; Domingo, Sebastián; Dozois, Eric J.; Duff, M. J.; Eglinton, Tim; Enrique-Navascues, J M; Espín‐Basany, Eloy; Evans, Martyn; Fearnhead, N.; Flatmark, Kjersti; Fleming, Fergal J.; Frizelle, Frank; Gallego, Mario Álvarez; García‐Granero, Eduardo; García-Sabrido, J.L.; Gentilini, Lorenzo; George, Mark; George, Vijay; Ghouti, Laurent; Giner, Francisco; Ginther, N; Glynn, R; Golda, Thomas; Griffiths, Ben; Harris, DA; JAW, Hagemans; Hanchanale, Vishwanath; Harji, Deena; Helewa, Ramzi M.; Hellawell, Giles; Heriot, Alexander G.; Hochman, David; Hohenberger, Werner; Holm, T.; Hompes, Roel; Jenkins, Jordan; Kaffenberger, Samuel D.; Kandaswamy, G V; Kapur, Sandeep; Kanemitsu, Yukihide; Kelley, S R; Keller, Deborah S.; Khan, Mohiuddeen; Kim, H; Kim, H J; Koh, Christopher; Nfm, Kok; Kokelaar, R; Kristensen, Helle; Kroon, Hidde M.; Kusters, Miranda; Lago, Vanessa Carvalho do; Larsen, Stein Gunnar; Larson, D W; Law, WL; Laurberg, Søren; Lee, P J; Limbert, M; Lydrup, Marie Louise; Lyons, Arnold R.; Lynch, A. C.; Mantyh, Christopher R.; Mathis, Kellie L.; Cfs, Margues; Martling, Anna; WJHJ, Meijerink; Merkel, Susanne; Mehta, Akash; DR, McArthur; FD, McDermott; JS, McGrath; Malde, Sachin; Mirnezami, A.; Monson, J. R. T.; Morton, Jasmine; Mullaney, Tamara G.; Negoi, Ionuț; Jwm, Neto; Ng, Jmk; Nguyen, Binh P.; Nielsen, Michael Bachmann; Gap, Nieuwenhuijzen; Nilsson, Per J.; Oliver, Alex; O’Dwyer, S T; Palmer, Gabriella Jansson; Pappou, Emmanouil P.; Park, J; Patsouras, Dimitrios; Pellino, Gianluca; Peterson, Alexandra; Poggioli, Gilberto; Proud, David; Quinn, Martha; Quyn, Aaron; Radwan, Rami; Rasmussen, Peter; Rausa, Emanuele; Regenbogen, Scott E.; Renehan, Andrew G; Rocha, Rafael Ramos da; Rochester, Mark; Rohila, Jitender; Rothbarth, Joost; Rottoli, Matteo; Roxburgh, C; Hjt, Rutten; Ryan, E. James; Safar, Bashar; Sagar, Pallavi; Sahai, Amit; Saklani, Avanish; Sammour, Tarik; Sayyed, Rameez; AMP, Schizas; Schwarzkopf, Eugenia; Scripcariu, Viorel; Selvasekar, Chelliah; Shaikh, I.; Shida, Dai; Simpson, A.; Smart, Neil; Smart, Philip; Smith, Julia; Solbakken, Arne M.; Solomon, Michael J.; Sørensen, Mette Møller; Steele, Scott R.; Steffens, Daniel; Stitzenberg, Karyn B.; Stocchi, Luca; Stylianides, N; Swartling, Torbjörn; Sumrien, H; Sutton, Paul; Swartking, T; Tan, Eric J.; Taylor, Claire; Teras, J; Thurairaja, Ramesh; Toh, Ee‐Lin; Tsarkov, Petr; Tsukada, Yuichiro; Tsukamoto, Shunsuke; Tuech, J J; Turner, William H.; Tuynman, Jurriaan B.; Ramshorst, Gabriëlle H. van; Zoggel, D. M. G. I. van; Vásquez-Jiménez, W; Verhoef, Cornelis; Vizzielli, Giuseppe; ELK, Voogt; Uehara, Kay; Wakeman, Chris; Warrier, Satish; Wasmuth, Hans H.; Weber, K; Weiser, Martin R.; Jmd., Wheeler; Wild, Jeremy; Wilson, Mitchell P; Wolthuis, Albert; Yano, H; Yip, Benjamin Cherng Hann; Yip, Jeremy; Yoo, Ri Na; Zappa, Marco; Winter, Desmond C.; Tekkis, Paris

doi:10.1002/bjs.11893

Cited by 7 publications

(3 citation statements)

References 5 publications

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“…The SARS-CoV-2 pandemic deeply affected surgical practice globally, with a reduction of emergency admissions and surgical procedures-for several reasons, including staff shortages, healthcare workers fear of infections [3,7,[14][15][16][17][18]-eventually impacting patients suffering from colorectal cancer. [2,19,20] Evidence supports the feasibility and safety of surgery for common colorectal conditions that, even if non-emergent, might impair patient's quality of life and long-term survival if treatment is delayed [21][22][23]. However, it is important that strategies are developed to mitigate the risk of complications related to perioperative SARS-CoV-2 infection [11,15,[20][21][22][24][25][26][27][28][29]-which is reported to have a detrimental effect on short-term outcomes of surgery [30].…”

Section: Discussionmentioning

confidence: 99%

Feasibility and usability of a regional hub model for colorectal cancer services during the COVID-19 pandemic

et al. 2022

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The outbreak of the COVID-19 pandemic produced unprecedented challenges, at a global level, in the provision of cancer care. With the ongoing need in the delivery of life-saving cancer treatment, the surgical management of patients with colorectal cancer required prompt significant transformation. The aim of this retrospective study is to report the outcome of a bespoke regional Cancer Hub model in the delivery of elective and essential colorectal cancer surgery, at the height of the first wave of the COVID-19 pandemic. 168 patients underwent colorectal cancer surgery from April 1st to June 30th of 2020. Approximately 75% of patients operated upon underwent colonic resection, of which 47% were left-sided, 34% right-sided and 12% beyond total mesorectal excision surgeries. Around 79% of all resectional surgeries were performed via laparotomy, and the remainder 21%, robotically or laparoscopically. Thirty-day complication rate, for Clavien–Dindo IIIA and above, was 4.2%, and 30-day mortality rate was 0.6%. Re-admission rate, within 30 days post-discharge, was 1.8%, however, no patient developed COVID-19 specific complications post-operatively and up to 28 days post-discharge. The established Cancer Hub offered elective surgical care for patients with colorectal cancer in a centralised, timely and efficient manner, with acceptable post-operative outcomes and no increased risk of contracting COVID-19 during their inpatient stay. We offer a practical model of care that can be used when elective surgery “hubs” for streamlined delivery of elective care needs to be established in an expeditious fashion, either due to the COVID-19 pandemic or any other future pandemics.

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Section: Discussionmentioning

confidence: 99%

Feasibility and usability of a regional hub model for colorectal cancer services during the COVID-19 pandemic

et al. 2022

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“…Therefore, it brings serious concerns about shortages of material/human resources, Japanese academic societies announced the recommendation of treatment for cancer in the COVID-19 pandemic, as have academic societies worldwide [9,10]. Previous studies have indicated that the COVID-19 pandemic has had an impact on cancer treatment, such as a decrease in the number of operations for patients with malignant tumors [11,12]. However, few studies have reported general effects, such as a decrease of hospital admissions related to the impact of the COVID-19 pandemic in the field of oncology.…”

Section: Introductionmentioning

confidence: 99%

The impact of the coronavirus disease 2019 (COVID-19) outbreak on cancer practice in Japan: using an administrative database

Itoshima

Asami

Shin

et al. 2020

Preprint

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Background: Recent researches reported the impact of the coronavirus disease 2019 (COVID - 19) pandemic on the clinical practice of specific type cancers. The aim of this study was to reveal the impact of the COVID-19 outbreak on the clinical practice of various cancers. Methods: We included hospitalized patients aged 18 years or older diagnosed between July 2018 and June 2020 with one of the top 12 most common cancers in Japan (colon/rectum, lung, gastric, breast, bladder & urinary tract, pancreas, non-Hodgkin lymphoma, liver, prostate, esophagus, uterus, and gallbladder & biliary tract) using Diagnostic Procedure Combination data, an administrative database in Japan. The intervention was defined April 2020 based on a declaration of emergency from Japanese government. The change volume of number of monthly admissions with each cancer was tested by interrupted time series (ITS) analysis, and monthly cases with radical surgery or chemotherapy for each cancer were descripted. Results: 403,344 cases were included during the study period. The most common cancer was colon/rectum (20.5%), followed by lung (17.5%). In almost cancer cases, the number of admissions decreased in May 2020. In particular, colorectal, lung, gastric, breast, uterine, or esophageal cancer cases decreased by over 10%. The number of admissions with surgery or chemotherapy decreased in colorectal, lung, gastric, breast, uterine, or esophageal cancer. ITS analysis indicated that cases with gastric or esophageal cancer were affected more than other type of cancer. Conclusions: The COVID-19 outbreak has a negative impact on the number of admission cases with cancer; the magnitude of impact varied by cancer diagnosis.

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“…Even so, Beijing experienced two waves of the COVID-19 pandemic, greatly influencing people’s daily lives and hospitalization. Articles have been published to share the impact of the COVID-19 pandemic 3 , 4 . However, evidence of its impact on patients with rectal cancer is sparse.…”

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confidence: 99%

Impact of COVID-19 on treatment modalities and short-term outcomes of rectal cancer following neoadjuvant chemoradiotherapy: a retrospective study

Dong

Zhang

et al. 2021

British Journal of Surgery

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The impact of the COVID-19 pandemic on the Management of Locally Advanced Primary/Recurrent Rectal Cancer

Cited by 7 publications

References 5 publications

Feasibility and usability of a regional hub model for colorectal cancer services during the COVID-19 pandemic

Feasibility and usability of a regional hub model for colorectal cancer services during the COVID-19 pandemic

The impact of the coronavirus disease 2019 (COVID-19) outbreak on cancer practice in Japan: using an administrative database

Impact of COVID-19 on treatment modalities and short-term outcomes of rectal cancer following neoadjuvant chemoradiotherapy: a retrospective study

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