The Impact of the COVID-19 Pandemic on People with HIV in Victoria, Australia: 1 Year Later

Weerasuria, Mihiri; Ko, Christy; Ehm, Adam; O’Bryan, Jessica; McMahon, James; Woolley, Ian; Hoy, Jennifer; Lau, Jillian S.Y.

doi:10.1089/aid.2022.0048

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Social distancing and isolation during the COVID-19 pandemic may also have triggered anxieties related to experiences of HIV-related stigma, leading to increases in perceived and internalized stigma [32]. Although many of the measures used to reduce community transmission of COVID-19 have now been removed in Australia, lasting impacts remain that should be considered in the design and implementation of psychosocial interventions for older adults living with HIV [17,68].…”

Section: Limitationsmentioning

confidence: 99%

Quality of life among people living with HIV aged 50 years and over in Australia: Identifying opportunities to support better ageing

Dawe,

Cassano,

Keane

et al. 2023

HIV Medicine

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ObjectivesImproved life expectancy has led to an ageing population of people living with HIV in most countries. Research on ageing among people living with HIV has predominantly focused on physical and health‐related quality of life rather than multidimensional quality of life. We measured quality of life among older people living with HIV in Australia and identified opportunities to guide the development and implementation of appropriate interventions.MethodsIn a national health and wellbeing survey of Australian people living with HIV, participants aged ≥50 years completed additional questions relevant to ageing. Quality of life was measured using PozQoL, a validated multidimensional instrument assessing quality of life among people living with HIV (range 1–5). Exploratory bivariate analyses aimed to identify sociodemographic characteristics associated with quality of life. Adjusted linear regressions aimed to assess changes in PozQoL score associated with recent experiences (last 12 months) of four exposures: food insecurity, HIV‐related stigma, isolation from the HIV community, and difficulties accessing non‐HIV health services.ResultsAmong 319 older people living with HIV, the mean PozQol score was 3.30 (95% confidence interval [CI] 3.20–3.39). In bivariate analyses, PozQol scores were significantly higher among participants who were older (p = 0.006), had higher educational attainment (p = 0.009), were in a relationship (p = 0.005), were employed (p = 0.005), and had a higher income (p = 0.001). In adjusted regression models, PozQoL scores were lower among participants who reported recent experiences of food insecurity (β −0.49; 95% CI −0.74 to −0.24), stigma (β −0.53; 95% CI −0.73 to −0.33), isolation from the HIV community (β −0.49; 95% CI −0.70 to −0.29), and difficulties accessing non‐HIV health services (β −0.50; 95% CI −0.71 to −0.30).ConclusionsOverall, older people living with HIV in this study had a moderate quality of life. Our findings suggest that HIV services should integrate programmes to support economic security and foster connections within the HIV community and across health services.

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Section: Limitationsmentioning

confidence: 99%

Quality of life among people living with HIV aged 50 years and over in Australia: Identifying opportunities to support better ageing

Dawe,

Cassano,

Keane

et al. 2023

HIV Medicine

Self Cite

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“…Moreover, the pandemic has had an unprecedented impact on health systems, including those affecting people with HIV (PWH), who experience disproportionately high levels of noninfectious comorbidities, which place them at a higher risk of adverse outcomes following SARS-CoV-2 infection [1]. PWH have reported changes in service provision, challenges in accessing care, and negative impacts on personal relationships, employment, and income due to COVID-19 [2,3].…”

Section: Introductionmentioning

confidence: 99%

Immunogenicity, effectiveness and safety of SARS-CoV-2 vaccination in people living with HIV: A systematic review and meta-analysis

Griffin

Mangalore

Hoy

et al. 2023

Aids

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Objectives: People with HIV (PWH) experience a greater risk of morbidity and mortality following COVID-19 infection, and poorer immunological responses to several vaccines. We explored existing evidence regarding the immunogenicity, effectiveness, and safety of SARS-CoV-2 vaccines in PWH compared with controls. Methods: We conducted a systematic search of electronic databases from January 2020 until June 2022, in addition to conference databases, to identify studies comparing clinical, immunogenicity, and safety in PWH and controls. We compared results between those with low (<350 cells/μl) and high (>350 cells/μl) CD4+ T-cell counts where possible. We performed a meta-analysis of seroconversion and neutralization responses to calculate a pooled risk ratio as the measure of effect. Results: We identified 30 studies, including four reporting clinical effectiveness, 27 immunogenicity, and 12 reporting safety outcomes. PWH were 3% [risk ratio 0.97, 95% confidence interval (95% CI) 0.95–0.99] less likely to seroconvert and 5% less likely to demonstrate neutralization responses (risk ratio 0.95, 95% CI 0.91–0.99) following a primary vaccine schedule. Having a CD4+ T-cell count less than 350 cells/μl (risk ratio 0.91, 95% CI 0.83–0.99) compared with a CD4+ T-cell count more than 350 cells/μl, and receipt of a non-mRNA vaccine in PWH compared with controls (risk ratio 0.86, 95% CI 0.77–0.96) were associated with reduced seroconversion. Two studies reported worse clinical outcomes in PWH. Conclusion: Although vaccines appear well tolerated in PWH, this group experience poorer immunological responses following vaccination than controls, particularly with non-mRNA vaccines and low CD4+ T-cell counts. PWH should be prioritized for mRNA COVID-19 vaccines, especially PWH with more advanced immunodeficiency.

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Perceived health-related quality of life in people living with HIV co-infected with SARS-CoV-2 in France

Amboise,

Yaya,

Yombo-Kokule

et al. 2024

Qual Life Res

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Purpose We aimed to assess health-related quality of life (HRQL) and its correlates among people living with HIV/AIDS (PLWHA) co-infected with SARS-CoV-2 in France. Methods This cross-sectional was study conducted among PLWHA co-infected with SARS-CoV-2. HRQL was measured using the four dimensions of the PROQOL-HIV scale. Factors associated with each dimension were identified using linear regression. Results mean (SD) scores for HRQL dimensions: 76.7 (± 21.1) for Physical Health and Symptoms (PHS), 79.2 (± 23.6) for Social Relationships (SR), 67.3 (± 27.4) for Mental and Cognitive (MC), and 83.9 (± 16.5) for Treatment Impact (TI). Employment status and COVID-19 knowledge were associated with higher PHS score, while blood transfusion-acquired HIV, CDC HIV, hospital discharge instructions, and self-reported symptoms were associated with lower PHS score. Couple status was associated with higher SR score, whereas, hospital discharge instructions, CDC HIV stage C, drug injection-acquired HIV, self-reported symptoms, and COVID-19 vulnerability perception were associated with lower SR score. Employment status and French birth were associated with higher MC score, while female sex, detectable HIV viral load, hospital discharge instructions, COVID-19 vulnerability perception, smoking, and self-reported symptoms were associated with lower MC score. French birth and homosexual/bisexual relationships-acquired HIV were associated with higher TI score, while detectable HIV viral load, psychiatric disorders, and self-reported symptoms were associated with lower TI score Conclusion Among PLWHA co-infected with SARS-CoV-2, the scores of HRQL were impaired, particularly in the MC dimension. Findings underscore the multidimensional nature of HRQL, with notable variations across different dimensions. Understanding these correlates is crucial for tailored interventions aimed at improving the well-being of this population.

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The Impact of the COVID-19 Pandemic on People with HIV in Victoria, Australia: 1 Year Later

Cited by 3 publications

References 4 publications

Quality of life among people living with HIV aged 50 years and over in Australia: Identifying opportunities to support better ageing

Quality of life among people living with HIV aged 50 years and over in Australia: Identifying opportunities to support better ageing

Immunogenicity, effectiveness and safety of SARS-CoV-2 vaccination in people living with HIV: A systematic review and meta-analysis

Perceived health-related quality of life in people living with HIV co-infected with SARS-CoV-2 in France

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