The impact of the COVID-19 pandemic on cancer care

Richards, Mike; Anderson, Michael; Carter, Paul; Ebert, Benjamin L.; Mossialos, Elías

doi:10.1038/s43018-020-0074-y

Cited by 450 publications

(484 citation statements)

References 12 publications

Supporting

Mentioning

447

Contrasting

Unclassified

Order By: Relevance

“…This led to consensus guidance from the British Society of Gastroenterology, American College of Gastroenterology, European Society of Gastrointestinal Endoscopy and Asian Pacific Society for Digestive Endoscopy that elective endoscopies should be suspended [ 11 ]. This resulted in a 90% reduction in the number of endoscopies undertaken in April 2020 in the UK, compared with the first 3 months of 2020, based on data from the UK National Endoscopy Database [ 12 , 16 ]. IR availability has allowed for the continued insertion of feeding tubes or biliary intervention with fluoroscopy, which in certain centres may have undergone the endoscopy route first-line, with smaller decreases in cases observed (22–27%).…”

Section: Discussionmentioning

confidence: 99%

The Impact of COVID-19 on Interventional Radiology Services in the UK

Zhong

Datta

Gordon

et al. 2020

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

Introduction The coronavirus disease 2019 (COVID-19) has created unprecedented challenges on the healthcare system. The aim of this multi-centre study was to measure the impact of COVID-19 on IR services in the UK. Material and Methods Retrospective cross-sectional study of IR practice in six UK centres during the COVID-19 pandemic was carried out. All therapeutic IR procedures were identified using the respective hospital radiology information systems and COVID-19 status found on the hospital patient record systems. The total number of therapeutic IR procedures was recorded over two time periods, 25/03/2019–21/04/2019 (control group) and 30/03/2020–26/04/2020 (COVID-19 group). The data points collected were: procedure type, aerosol-generating nature, acute or elective case, modality used, in- or out-of-hours case and whether the procedure was done at the bedside (portable). Results A 31% decrease in overall number of IR procedures was observed during COVID-19 compared to the control group (1363 cases vs 942 cases); however, the acute work decreased by only 0.5%. An increase in out-of-hours work by 10% was observed. COVID-19 was suspected or laboratory proved in 9.9% of cases (n = 93), and 15% of total cases (n = 141) were classed as aerosol-generating procedures. A 66% rise in cholecystostomy was noted during COVID-19. Image-guided ablation, IVC filters, aortic stent grafting and visceral vascular stenting had the greatest % decreases in practice during COVID-19, with 91.7%, 83.3%, 80.8% and 80.2% decreases, respectively. Conclusion During the global pandemic, IR has continued to provide emergency and elective treatment highlighting the adaptability of IR in supporting other specialties.

show abstract

Section: Discussionmentioning

confidence: 99%

The Impact of COVID-19 on Interventional Radiology Services in the UK

Zhong

Datta

Gordon

et al. 2020

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

show abstract

“…Our dataset explores the impact of COVID-19 on cancer management. Beyond the emerging data raising the concern of fewer cancer diagnoses during the COVID-19 pandemic 20 , the impact on ongoing cancer care, including delays of treatment and halting of clinical trials, has been identified 21 . Our dataset identified a high incidence of delays, but the median time to anticancer systemic therapy or rescheduled surgery was <1 month.…”

Section: Discussionmentioning

confidence: 99%

Determinants of the outcomes of patients with cancer infected with SARS-CoV-2: results from the Gustave Roussy cohort

et al. 2020

View full text Add to dashboard Cite

B y early March 2020, the spread of the coronavirus disease 2019 (COVID-19) outbreak had reached the Paris area, France. Since then, all medical resources have been reorganized to handle the pandemic. As a tertiary cancer center, Gustave Roussy has followed two objectives: define processes to safely sustain cancer care in a secured environment and reorganize internally to adapt its capacities to hospitalize patients with cancer and COVID-19 illness. Patients with cancer have been considered at increased risk of COVID-19, on the rationale of the increased systemic immunosuppressive state caused by the underlying malignancy and anticancer treatments. The first report from a retrospective cohort in China suggested that patients with cancer were observed to have a higher risk of severe events (for example, a composite endpoint of intensive care unit (ICU) admission, invasive ventilation or death) compared with patients without cancer (seven (39%) of 18 patients versus 124 (8%) of 1,572 patients; P = 0.0003) and that patients with cancer deteriorated more rapidly than those without cancer 1. While general determinants of COVID-19 severity have emerged from large cohorts from China and Italy 2,3 , limited data are available on the specificity of patients with cancer to help the oncology community to identify patients at risk of severe COVID-19. Furthermore, the impact of COVID-19 infection on ongoing cancer care is unexplored. This study investigated the determinants of clinical worsening and death, as well as the impact on cancer care, for the first patients sequentially managed for COVID-19 and cancer in an academic tertiary cancer center. Results Patient population. From 24 March 2020 until 29 April 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detected in 196 (12%) of 1,633 tests performed internally at the Gustave Roussy Cancer Centre. Overall, 209 patients were identified (including a few identified by PCR with reverse transcription (RT-PCR) performed at another facility and some diagnosed by computed tomography scan alone) and the final study population included 178 adult patients. The following were reasons for exclusion: pediatric population (six patients); non-cancer patients (19 patients); and COVID-19 ultimately ruled out (six patients). Baseline demographics, comorbidities and underlying cancer characteristics for

show abstract

“…Psychological well-being of healthcare workers during the COVID-19 pandemic shown that vulnerable groups, namely those who are immunocompromised, with underlying medical conditions are at higher risk of life-threatening illness from COVID-19. 27,28 The knowledge of this increased risk may have worked as an additional stressor for our healthcare workers with pre-existing illnesses. Perhaps more efforts can be made to address the concerns of this vulnerable group of healthcare workers through ensuring that their exposure to COVID-19 patients are adjusted accordingly to their health risk status.…”

Section: Role Of Prior Medical Conditionsmentioning

confidence: 99%

Asian-Pacific perspective on the psychological well-being of healthcare workers during the evolution of the COVID-19 pandemic

et al. 2020

View full text Add to dashboard Cite

Background The coronavirus disease 2019 (COVID-19) pandemic has led to significant strain on front-line healthcare workers. Aims In this multicentre study, we compared the psychological outcomes during the COVID-19 pandemic in various countries in the Asia-Pacific region and identified factors associated with adverse psychological outcomes. Method From 29 April to 4 June 2020, the study recruited healthcare workers from major healthcare institutions in five countries in the Asia-Pacific region. A self-administrated survey that collected information on prior medical conditions, presence of symptoms, and scores on the Depression Anxiety Stress Scales and the Impact of Events Scale-Revised were used. The prevalence of depression, anxiety, stress and post-traumatic stress disorder (PTSD) relating to COVID-19 was compared, and multivariable logistic regression identified independent factors associated with adverse psychological outcomes within each country. Results A total of 1146 participants from India, Indonesia, Singapore, Malaysia and Vietnam were studied. Despite having the lowest volume of cases, Vietnam displayed the highest prevalence of PTSD. In contrast, Singapore reported the highest case volume, but had a lower prevalence of depression and anxiety. In the multivariable analysis, we found that non-medically trained personnel, the presence of physical symptoms and presence of prior medical conditions were independent predictors across the participating countries. Conclusions This study highlights that the varied prevalence of psychological adversity among healthcare workers is independent of the burden of COVID-19 cases within each country. Early psychological interventions may be beneficial for the vulnerable groups of healthcare workers with presence of physical symptoms, prior medical conditions and those who are not medically trained.

show abstract

The impact of the COVID-19 pandemic on cancer care

Cited by 450 publications

References 12 publications

The Impact of COVID-19 on Interventional Radiology Services in the UK

The Impact of COVID-19 on Interventional Radiology Services in the UK

Determinants of the outcomes of patients with cancer infected with SARS-CoV-2: results from the Gustave Roussy cohort

Asian-Pacific perspective on the psychological well-being of healthcare workers during the evolution of the COVID-19 pandemic

Contact Info

Product

Resources

About