The impact of socio-economic deprivation on incidence, treatment and mortality from prostate cancer in England, 1990–2010

Abstract

Objective: To explore any association between socioeconomic deprivation and prostate cancer diagnosis and/or treatment. Patients and methods: Data was extracted as follows: We gained the incident cases and staging from the National Cancer Data Repository, survival from the Cancer Information System, mortality from the Office for National Statistics, treatment data from Hospital Episode Statistics and National Clinical Analysis and Specialised Applications Team. Our analysis regarding socioeconomic deprivation was controlled for age distribution. Results: We recorded 518,453 diagnoses of prostate cancer; 174,579 prostate cancer deaths; 33,889 prostatectomies and 21,351 radiotherapy treatments. Incidence is increasing in all groups, but the highest is amongst the least deprived. Mortality is decreasing, with survival consistently better in the least deprived. Prostatectomies are more frequent in the least deprived; however, this gap is narrowing. Conclusions: Prostate cancer incidence, survival and treatment are associated with socioeconomic deprivation. Prostatectomy rates show a decrease in the gap of inequality. Multiple potential confounding factors, such as rates of prostate specific antigen (PSA) testing and access to health care are associated with socioeconomic deprivation. The unifying influences of Improving Outcomes Guidance and the National Treatment Guidelines are intended to counteract the above inequalities. Particularly in prostate cancer, where long-term gain depends on multiple factors, individualised treatment decisions are paramount.

Lugar de residencia y grado de marginación como factores pronóstico de supervivencia al cáncer de próstata en Veracruz, México

“…Los estudios analizados confirman la asociación entre el grado de deprivación o desventaja socioeconómica y la supervivencia al CP en otros países. En todos ellos se ha observado que la supervivencia es menor en los hombres con mayor deprivación socioeconómica comparado con los de niveles socioeconómicos más alto o más aventajados (14,21,(28)(29)(30) .…”

Influence of deprivation and rurality on patient-reported outcomes of men living with and beyond prostate cancer diagnosis in the UK: A population-based study

“…However, in England prostate cancer incidence is higher is rural areas [20]. Additionally, deprivation and rurality have been shown to impact on uptake of Prostate Specific Antigen (PSA) testing, stage of presentation and types of treatment received [18,21,22]. Men from more deprived areas have lower rates of PSA testing and more advanced stage of disease at presentation as do men living in rural areas [18,21].…”

Regional Variations in Quality of Survival Among Men with Prostate Cancer Across the United Kingdom

“…Prostate cancer is one of the most commonly diagnosed male cancers in the UK [1], with incidence and survival rates varying between and within the UK's four constituent countries (England, Scotland, Wales, and Northern Ireland [NI]) [1][2][3]. In particular, higher incidence and better survival are typically found in more affluent areas [1,4], possibly reflecting levels of active case finding through prostate-specific antigen (PSA) testing [5].…”