Abstract:Objective. To assess the influence of simvastatin vs. atorvastatin therapy on cognitive function in obese hypertensive patients. Design and methods. This open clinical trial included 40 patients (mean age 47,7 ± 5,6 years). 20 patients received simvastatin and 20 — atorvastatin. Monotherapy lasted 12 months. At baseline and 12 months later, all participants underwent neuropsychological testing and cognitive evoked potential (P300) to assess cognitive function. Results. 12-month therapy with simvastatin and ato… Show more
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