The Impact of Severe Asthma on the Quality of Life: a Systematc Review

Likhar, N; Mothe, RK; Esam, Hariprasad; Badgujar, Lohit; Kanukula, Raju; Dang, Anh

doi:10.1016/j.jval.2015.09.2673

Cited by 3 publications

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“…Good management of asthma is also essential to reduce the economic burden of asthma. If not controlled properly, asthma can affect daily activities and result in physical, emotional and social limitations which can impair quality of life and even be fatal [ Van Lieshout and MacQueen, 2012 ; Likhar et al 2015 ]. According to the Global Initiative for Asthma (GINA), the long-term goals of asthma control are symptom control and risk reduction [ GINA, 2015 ].…”

Section: Introductionmentioning

confidence: 99%

Uncontrolled asthma and its risk factors in adult Chinese asthma patients

Zhong

Lin

Zheng

et al. 2016

Ther Adv Respir Dis

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Background:Asthma affects a large number of patients in China, but relatively little is known about asthma management among Chinese patients. This study aims to estimate asthma control rate among adult Chinese patients and to identify predictors associated with uncontrolled asthma.Methods:A total of 4125 asthma patients aged ⩾17 years and representing all regions of mainland China except Tibet were surveyed. Asthma control status was assessed using the Asthma Control Test (ACT) and classified as controlled (ACT score ⩾ 20) and uncontrolled (ACT score ⩽ 19). A multivariate logistic regression model was used to identify predictors associated with uncontrolled asthma from the factors including demographics, rhinitis, allergic rhinitis, and treatment adherence.Results:Asthma was controlled in 44.9%, and uncontrolled in 55.1% of the study participants. High rates of uncontrolled asthma were found in patients with treatment nonadherence (77.3%), poor adherence (66.2%), no schooling (64.8%), or obesity (62.9%). The risk of uncontrolled asthma was much higher in the treatment nonadherence group than the complete adherence group [odds ratio (OR) = 4.55 (3.68–5.62), p < 0.001]. Other predictors for uncontrolled asthma included concomitant rhinitis [OR = 1.31 (1.14–1.50), p < 0.001], obesity [OR = 1.31 (1.05–1.64), p = 0.019], asthma duration > 3 years [OR = 1.22 (1.07–1.39), p = 0.004] and age ⩾ 45 years [OR = 1.23 (1.07–1.41), p = 0.004].Conclusions:About half of the participants in this study had uncontrolled asthma. Treatment nonadherence is one of the significant predictors, which is very strongly associated with uncontrolled asthma. Efforts should be prioritized to promote patients’ treatment adherence to improve asthma control while attention is needed on rhinitis or obesity.

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Section: Introductionmentioning

confidence: 99%

Uncontrolled asthma and its risk factors in adult Chinese asthma patients

Zhong

Lin

Zheng

et al. 2016

Ther Adv Respir Dis

View full text Add to dashboard Cite

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“…5 Lack of asthma control can impair the quality of life by affecting daily activities, resulting in physical, social, and emotional limitations. [6][7][8] Hence, asthma control is critical to reduce the economic burden of asthma and enhance the quality of life.…”

Section: Introductionmentioning

confidence: 99%

Asthma Medication Prescribing Practices in Pediatric Office Visits

Rege

Kavati

Ortiz

et al. 2019

Clin Pediatr (Phila)

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This cross-sectional study examined how asthma control, demographic, and clinical characteristics are associated with the use of asthma medications in pediatric office visits in the United States. Data from the 2012-2015 National Ambulatory Medical Care Survey included patients aged 6 to 17 years, with asthma as a primary diagnosis (International Classification of Diseases, Ninth Revision, Clinical Modification, code 493.xx). Descriptive weighted analysis evaluated asthma medication use. Multivariable logistic regression examined characteristics associated with asthma prescribing practices. An estimated 2.5 million pediatric office visits were made annually for asthma. The majority of asthma visits involved males (59.3%), children aged 6 to 11 years (54.8%), and whites (73.6%). Several clinical and demographic characteristics contributed to the variations in overall asthma medication use as well as specific drug classes. Lack of documentation of asthma control and uncontrolled asthma were associated with oral corticosteroid and inhaled corticosteroid use in pediatric asthma patients, but not with overall asthma medication use.

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The illness burden of severe asthma contrasted to people with mild-to-moderate asthma: a qualitative study

Majellano,

Yorke,

Clark

et al. 2024

ERJ Open Res

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IntroductionDisabling symptoms of asthma including breathlessness, cough, wheeze and chest tightness largely impact quality of life, however how these symptoms impact people with asthma of different severity levels remains unknown. This study aimed to compare and characterise patient experience of symptoms and their burden, quality of life, and medication preferences of people with severe asthma against those of people with mild/moderate asthma.MethodsA multisite qualitative study involving two focus group and semi-structured interviews of adults with severe asthma were undertaken in Australia and UK. Interview were also undertaken in people with mild to moderate asthma. Audio recordings were transcribed and analysed thematically.ResultsParticipants in both groups had a mean±sdage of 57+12 years. Between groups, 74% of participants were female and 81% lived with family. Themes were identified: 1) what is asthma and most bothersome symptoms: both groups reported breathlessness as the most bothersome symptom; 2) Impacts on life: disease related impact differed as people with severe asthma reported significant burden in their quality of life; 3) personalised and responsive care: severe asthma interviewees preferred injectable biologic therapy as a mode of treatment administration.DiscussionPeople with asthma are burdened by breathlessness and cough and other disabling symptoms resulting in impaired quality of life. Understanding the experiences of people with asthma of different severities can improve patient-clinician partnership.

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The Impact of Severe Asthma on the Quality of Life: a Systematc Review

Cited by 3 publications

References 0 publications

Uncontrolled asthma and its risk factors in adult Chinese asthma patients

Uncontrolled asthma and its risk factors in adult Chinese asthma patients

Asthma Medication Prescribing Practices in Pediatric Office Visits

The illness burden of severe asthma contrasted to people with mild-to-moderate asthma: a qualitative study

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