The impact of prostatectomy and brachytherapy in patients with localized prostate cancer

Reis, F. Carmo; Netto, Nelson Rodrígues; Reinato, J.A.S.; Thiel, Marcelo; Zani, E.L.

doi:10.1023/b:urol.0000034686.55747.a5

Cited by 12 publications

(11 citation statements)

References 14 publications

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“…The RP group experienced a higher level of urinary dysfunction compared to the other treatment groups. This is consistent with some researchers 9,14 who have found that patients who undergo RP show some level of urinary dysfunction, but is inconsistent with others 15 . This highlights the variability in the definition of incontinence used and how this can impact on the study results.…”

Section: Discussionsupporting

confidence: 86%

Long‐term experience of residual symptoms following treatment for localized prostate cancer: An Australian sample

Wootten

Burney

Frydenberg

et al. 2007

Asia-Pac J Clncl Oncology

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Aim:To assess the degree of residual urinary and sexual dysfunction experienced by patients treated for localized prostate cancer with radical prostatectomy (RP), external beam radiotherapy (EBRT) or EBRT plus hormone therapy (EBRT/HT) in an Australian sample. Methods: This was a cross-sectional survey of 150 patients who had undergone treatment for localized prostate cancer a mean of 4.93 years prior to the study. It was part of a larger study investigating the psychological adjustment of patients and their partners. Fifty-five patients had undergone RP, 67 patients had undergone EBRT and 28 patients had undergone EBRT/HT for localized prostate cancer. The patients completed the University of California Los Angeles-prostate cancer index to determine the level of residual sexual and urinary dysfunction and bother as well as their socio-demographic characteristics. Results: In the RP group, 34.5% of patients reported urinary leakage every day. Only one RP patient (1.8%) reported this as a significant problem. Inability to achieve an erection was reported by 41.8% of the RP group, 34.3% of the EBRT group and 46.4% of the EBRT/HT group. ancova indicated a significant difference in mean urinary function scores across treatment groups. The RP group showed significantly worse urinary function compared to the other treatment groups; however, this was not perceived to be a significant problem by most of the survivors. Age was significantly associated with sexual function. Conclusion: Patients treated for localized prostate cancer face a high probability of living with long-term residual symptoms. The results of this study suggest that urinary and sexual dysfunction is still evident, even in patients treated more than 4 years ago. The findings are consistent with a growing body of research indicating that patients in the later stages of surviving cancer face significant quality of life issues.

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Section: Discussionsupporting

confidence: 86%

Long‐term experience of residual symptoms following treatment for localized prostate cancer: An Australian sample

Wootten

Burney

Frydenberg

et al. 2007

Asia-Pac J Clncl Oncology

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“…In this way we could ascertain that the same definition was used for the side effects when comparing different treatments. This yielded 18 studies . Data were obtained for genito‐urinary morbidity (incontinence requiring two pads or more per day), gastrointestinal morbidity (diarrhoea) and erectile dysfunction (erections insufficient for intercourse).…”

Section: Methodsmentioning

confidence: 99%

Choice between prostatectomy and radiotherapy when men are eligible for both: a randomized controlled trial of usual care vs decision aid

Tol-Geerdink¹,

Leer²,

Weijerman³

et al. 2012

BJU International

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Trial NTR1334What's known on the subject? and What does the study add?• Many patients are eligible for more than one treatment option for prostate cancer. In usual care, urologists have a large influence on the treatment choice. Decision aids, providing balanced information on the pros and cons of different treatment options, improve the match between patient preferences and treatment received.• In men eligible for both surgery and external beam radiotherapy, treatment choice differed by hospital. Across the participating hospitals, the decision aid consistently led to fewer patients remaining undecided on their treatment preference and more patients choosing brachytherapy. Objectives• To examine the treatment choice for localized prostate cancer in selected men who were eligible for both prostatectomy and radiotherapy.• To examine whether increased patient participation, using a decision aid, affected the treatment choice. Patients and Methods• From 2008 to 2011, 240 patients with localized prostate cancer were enrolled from three separate hospitals.• They were selected to be eligible for both prostatectomy and external beam radiotherapy. Brachytherapy was a third option for about half of the patients.• In this randomized controlled trial, patients were randomized to a group which only discussed their treatment with their specialist (usual care group) and a group which received additional information from a decision aid presented by a researcher (decision aid group). The decision aid was based on a literature review.• Predictors of treatment choice were examined.

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“…Five years after diagnosis Health-Related Quality of Life (HRQOL) is equal or superior in prostate cancer patients than it is in the population [7]. Nevertheless, the extended treatment side effects persist years after treatment has ended, whereas patients treated by prostatectomy have major erectile dysfunction [7] and urinary incontinence [8] as compared with patients treated by brachytherapy. Watchful waiting could cause difficulties in discharging urine [9].…”

mentioning

confidence: 99%

“Between Men”: A psychosocial rehabilitation programme for men with prostate cancer

et al. 2007

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The impact of prostatectomy and brachytherapy in patients with localized prostate cancer

Cited by 12 publications

References 14 publications

Long‐term experience of residual symptoms following treatment for localized prostate cancer: An Australian sample

Long‐term experience of residual symptoms following treatment for localized prostate cancer: An Australian sample

Choice between prostatectomy and radiotherapy when men are eligible for both: a randomized controlled trial of usual care vs decision aid

“Between Men”: A psychosocial rehabilitation programme for men with prostate cancer

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