The impact of preoperative vitamin administration on skeletal status following sleeve gastrectomy in young and middle-aged women: a randomized controlled trial

Trabecular Bone Score Preceding and during a 2-Year Follow-Up after Sleeve Gastrectomy: Pitfalls and New Insights

“…As previously described, 62 patients were enrolled in a prospective, randomized clinical trial (Identifier: NCT02483026) to compare the effect of pre-operative vitamin administration vs. standard pre-surgical care on BMD among female candidates for SG, with a follow-up at one [11] and two years after surgery [12]. The present longitudinal cohort study reports additional data concerning the bone health evaluation of these patients obtained at the time when the DXA scans were performed, namely, their trabecular bone score values.…”

“…In total, 54 patients completed follow-up at 12 months. No differences were observed between the groups at 12 months of DXA follow-up [11], and thus, a combined group of 33 patients had an additional DXA scan performed at 24 months [12]. At baseline, the inclusion criteria were women aged 18-65 years with a BMI ≥ 40 kg/m 2 or BMI ≥ 35 kg/m 2 with comorbidities.…”

“…To the best of our knowledge, no such study has been published based on patients after SG. We recently showed that among 33 patients who were previously on DXA follow-up, at 1 and 2 years after SG, bone mineral density (BMD) decreased significantly in the total hip (with an increase between 1 and 2 years), whereas it remained stable in the spine [11,12]. The main goal of our current investigation was to evaluate the hypothesis that the TBS has valuable clinical relevance in patients undergoing SG despite their elevated BMI before surgery and that TBS may be impacted by SG during follow-up.…”

Nutritional Interventions for Patients with Severe Obesity Seeking Bariatric Surgery

“…Treating nutritional deficiencies after surgery can be complex, especially in light of patients’ limited adherence to clinical care and the supplementation regime during the postoperative period, particularly in the longer-term after the surgery [ 15 ]. In regard to routine supplementation regimes at the pre-surgical period, a few recent trials testing vitamin D loading at the pre-surgery period demonstrated some benefits for the pre- and postoperative levels of this vitamin as well as for some skeletal parameters, when combined with other interventions post BS (e.g., calcium supplements and physical activity) [ 16 , 17 , 18 ]. However, the impact of other supplementation programs targeting specific nutrients (e.g., iron, folate, vitamin B12, etc.)…”