The impact of premature extrauterine exposure on infants’ stimulus-evoked brain activity across multiple sensory systems

Mellado, Gabriela Schmidt; Pillay, Kirubin; Adams, Eleri; Alarcón, Ana; Andritsou, Foteini; Cobo,; Fry, Ria Evans; Fitzgibbon, Sean P.; Moultrie, Fiona; Baxter, Luke; Slater, Rebeccah

doi:10.1016/j.nicl.2021.102914

Cited by 16 publications

(17 citation statements)

References 91 publications

(117 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Birth is a unique event in life, and much still remains to be discovered about it. Few researchers only have so far taken into account the impact of the extrauterine environment, with its intense stimuli, on birth (Schwindt et al, 2018;De Asis-Cruz et al, 2020;Schmidt Mellado et al, 2022). The GABA excitatory/inhibitory shift may suggest a complete neurofunctional change from the fetal to the neonatal status (Long et al, 2005;Ben-Ari et al, 2007;Gatti et al, 2012;Sedmak et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…The GABA excitatory/inhibitory shift may suggest a complete neurofunctional change from the fetal to the neonatal status (Long et al, 2005;Ben-Ari et al, 2007;Gatti et al, 2012;Sedmak et al, 2016). The onset of an inhibitory activity can be associated with the newborn's response to the bombardment by extrauterine stimuli, different from intrauterine homeostasis (Maccari et al, 2017;André et al, 2018;Schwindt et al, 2018;Fagioli, 2019;De Asis-Cruz et al, 2020;Schmidt Mellado et al, 2022; Figure 2). In particular, GABA switch can be induced by light stimulation of the retina at birth; at the same time, GABA activity may determine a developmental change in retinal waves' dynamics (Sernagor et al, 2003;Maccione et al, 2014;Peerboom and Wierenga, 2021).…”

Section: Discussionmentioning

confidence: 99%

“…Observational studies define birth's time 0 as the moment when the newborn's thorax and pelvis pass through the birth canal (Rousseau et al, 2014). In this study, we take into account the existence of a hiatus between intrauterine and extrauterine condition, and only use the terms 'human life and human birth, ' to define the newborn's extrauterine existence, given new physiological conditions (Hillman et al, 2012;Morton and Brodsky, 2016;Schwindt et al, 2018;Schmidt Mellado et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

“…Extrauterine stimulation is a fundamental factor when considering brain maturation. After exposure to the extrauterine environment, the premature newborn's neurodevelopment is accelerated, in particular in relation to visual and tactile response (Schmidt Mellado et al, 2022). At birth, exposure to this new hyperstimulating environment happens abruptly and brain reaction is needed in a few seconds.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth

Polese

Riccio

Fagioli

et al. 2022

Front. Integr. Neurosci.

View full text Add to dashboard Cite

Developmental neuroscience research has not yet fully unveiled the dynamics involved in human birth. The trigger of the first breath, often assumed to be the marker of human life, has not been characterized nor has the process entailing brain modification and activation at birth been clarified yet. To date, few researchers only have investigated the impact of the extrauterine environment, with its strong stimuli, on birth. This ‘hypothesis and theory' article assumes the role of a specific stimulus activating the central nervous system (CNS) at human birth. This stimulus must have specific features though, such as novelty, efficacy, ubiquity, and immediacy. We propose light as a robust candidate for the CNS activation via the retina. Available data on fetal and neonatal neurodevelopment, in particular with reference to retinal light-responsive pathways, will be examined together with the GABA functional switch, and the subplate disappearance, which, at an experimental level, differentiate the neonatal brain from the fetal brain. In this study, we assume how a very rapid activation of retinal photoreceptors at birth initiates a sudden brain shift from the prenatal pattern of functions to the neonatal setup. Our assumption implies the presence of a photoreceptor capable of capturing and transducing light/photon stimulus, transforming it into an effective signal for the activation of new brain functions at birth. Opsin photoreception or, more specifically, melanopsin-dependent photoreception, which is provided by intrinsically photosensitive retinal ganglion cells (ipRGCs), is considered as a valid candidate. Although what is assumed herein cannot be verified in humans based on knowledge available so far, proposing an important and novel function can trigger a broad range of diversified research in different domains, from neurophysiology to neurology and psychiatry.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth

Polese

Riccio

Fagioli

et al. 2022

Front. Integr. Neurosci.

View full text Add to dashboard Cite

show abstract

“…A related question concerns the mechanisms involved in the effectiveness of shared reading sessions in preterm infants. Some research teams have reported a positive effect of music on cerebral maturation in preterm infants (56), with comparable findings regarding tactile stimulations (58). It is possible that the compensation of sensory deprivation contributes to a significant proportion of the effectiveness of such sensory-based stimulations programs for preterm infant in NICU.…”

Section: Clinical Challenges For Shared Reading Interventionsmentioning

confidence: 81%

A narrative review of the effect of parent–child shared reading in preterm infants

et al. 2022

View full text Add to dashboard Cite

The benefits of book-reading interventions on language development in full-term infants have been well investigated. Because children born preterm face a greater risk of cognitive, language and emotional impairments, this narrative review examines the theoretical evidence, empirical findings, and practical challenges for introducing such intervention to this population. The effect of shared book interventions on typically developing infants is mediated by three components: a linguistic aspect (i.e., exposure to enriched linguistic input), an interactive aspect (i.e., eliciting more synchronous and contingent communication), and a parental aspect (i.e., reducing parental stress and increasing sense of control). Parental shared book reading in a neonatal intensive care unit (NICU) was found to be feasible and well accepted. It provides concrete support for positive parenting in a highly stressful context. Preliminary evidence supports a positive effect of shared reading sessions in physiological parameters of preterm infants in NICU. One study showed that parental shared book reading in an NICU is associated with lower decline in language development during the first 24 months compared to a historical control group. Findings from a community-based birth cohort confirm the positive effect of this intervention on cognitive development with a 2-year-follow up. More structured clinical trials are now needed to confirm these preliminary findings. Questions remain about possible moderators of these interventions, in particular cultural features.

show abstract

Sensory event-related potential morphology predicts age in premature infants

Zandvoort,

van der Vaart,

Robinson

et al. 2024

Clinical Neurophysiology

View full text Add to dashboard Cite

The impact of premature extrauterine exposure on infants’ stimulus-evoked brain activity across multiple sensory systems

Cited by 16 publications

References 91 publications

The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth

The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth

A narrative review of the effect of parent–child shared reading in preterm infants

Sensory event-related potential morphology predicts age in premature infants

Contact Info

Product

Resources

About