The Impact of Pravastatin Therapy on Long-Term Outcome in Patients With Metabolic Syndrome Undergoing Complete Coronary Revascularization

Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017

“…In a study where patients who underwent PCI were followed up with for a long period, the relative risk for cardiovascular events in those with metabolic syndrome was 2.1-fold higher 777 ) . However, statin administration resulted in a significant decrease in total mortality by 44% and in coronary death by 47% 778 ) .…”

Clustering of Metabolic Syndrome Components Attenuates Coronary Plaque Regression During Intensive Statin Therapy in Patients With Acute Coronary Syndrome

“…Proximal to the culprit, n (%) 0 (0) 9 (29) 24 (35) 26 (31) 15 (29) (23) 10 (14) 17 (20) 14 (27) 0.310…”

Coronary Artery Disease

“…The JCAD, an observational study conducted in Japan, demonstrated that the risk of cardiovascular events in patients with three or more major risk factors is 1.3-fold higher than that observed in patients with two or less risk factors 5) . In a study in which patients who underwent percutaneous coronary intervention (PCI) were followed up for a long period, the relative risk of cardiovascular events in the patients with metabolic syndrome was 2.1-fold 26) ; however, statin treatment resulted in a significant decrease in total mortality of 44% and coronary death of 47% 27) .…”